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5B4C
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BU of 5b4c by Molmil
Crystal structure of H10N mutant of LpxH with manganese
Descriptor: GLYCEROL, MANGANESE (II) ION, UDP-2,3-diacylglucosamine hydrolase
Authors:Okada, C, Wakabayashi, H, Yao, M, Tanaka, I.
Deposit date:2016-04-03
Release date:2016-09-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
Sci Rep, 6, 2016
5UQ6
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BU of 5uq6 by Molmil
PIG PURPLE ACID PHOSPHATASE COMPLEXED WITH PHOSPHATE IN TWO COORDINATION MODES ALONG WITH A BRIDGING HYDROXIDE ION
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, HYDROXIDE ION, ...
Authors:Selleck, C, Guddat, L, Schenk, G, Clayton, D.
Deposit date:2017-02-06
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.182 Å)
Cite:Visualization of the Reaction Trajectory and Transition State in a Hydrolytic Reaction Catalyzed by a Metalloenzyme.
Chemistry, 23, 2017
5EQV
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BU of 5eqv by Molmil
1.45 Angstrom Crystal Structure of Bifunctional 2',3'-cyclic Nucleotide 2'-phosphodiesterase/3'-Nucleotidase Periplasmic Precursor Protein from Yersinia pestis with Phosphate bound to the Active site
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D-MALATE, FE (III) ION, ...
Authors:Minasov, G, Shuvalova, L, Brunzelle, J.S, Kiryukhina, O, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-11-13
Release date:2015-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:1.45 Angstrom Crystal Structure of Bifunctional 2',3'-cyclic Nucleotide 2'-phosphodiesterase/3'-Nucleotidase Periplasmic Precursor Protein from Yersinia pestis with Phosphate bound to the Active site.
To Be Published
2HYP
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BU of 2hyp by Molmil
Crystal structure of Rv0805 D66A mutant
Descriptor: BROMIDE ION, CACODYLATE ION, FE (III) ION, ...
Authors:Shenoy, A.R, Capuder, M, Draskovic, P, Lamba, D, Visweswariah, S.S, Podobnik, M.
Deposit date:2006-08-07
Release date:2006-12-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
J.Mol.Biol., 365, 2007
5WLY
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BU of 5wly by Molmil
E. coli LpxH- 8 mutations
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ...
Authors:Bohl, T.E, Aihara, H, Shi, K, Lee, J.K.
Deposit date:2017-07-28
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.
J. Biol. Chem., 293, 2018
5B4A
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BU of 5b4a by Molmil
Crystal structure of LpxH with lipid X in spacegroup P21
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, UDP-2,3-diacylglucosamine hydrolase
Authors:Okada, C, Wakabayashi, H, Yao, M, Tanaka, I.
Deposit date:2016-04-03
Release date:2016-09-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
Sci Rep, 6, 2016
5B4B
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BU of 5b4b by Molmil
Crystal structure of LpxH with lipid X in spacegroup C2
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, UDP-2,3-diacylglucosamine hydrolase
Authors:Okada, C, Wakabayashi, H, Yao, M, Tanaka, I.
Deposit date:2016-04-03
Release date:2016-09-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
Sci Rep, 6, 2016
5B49
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BU of 5b49 by Molmil
Crystal structure of LpxH with manganese from Pseudomonas aeruginosa
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Okada, C, Wakabayashi, H, Yao, M, Tanaka, I.
Deposit date:2016-04-03
Release date:2016-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
Sci Rep, 6, 2016
2KKN
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BU of 2kkn by Molmil
Solution NMR structure of Themotoga maritima protein TM1076: Northeast Structural Genomics Consortium target VT57
Descriptor: Uncharacterized protein
Authors:Cort, J.R, Yee, A, Garcia, M, Isern, N.G, Arrowsmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-06-26
Release date:2009-10-06
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution NMR structure of Themotoga maritima protein TM1076
To be Published
5B4D
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BU of 5b4d by Molmil
Crystal structure of H10N mutant of LpxH
Descriptor: GLYCEROL, UDP-2,3-diacylglucosamine hydrolase
Authors:Okada, C, Wakabayashi, H, Yao, M, Tanaka, I.
Deposit date:2016-04-03
Release date:2016-09-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of the UDP-diacylglucosamine pyrophosphohydrase LpxH from Pseudomonas aeruginosa
Sci Rep, 6, 2016
5C1V
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BU of 5c1v by Molmil
CRYSTAL STRUCTURE ANALYSIS OF CATALYTIC SUBUNIT OF HUMAN CALCINEURIN
Descriptor: FE (III) ION, PHOSPHATE ION, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, ...
Authors:Guasch, A, Fita, I, Perez-Luque, R, Aparicio, D, Aranguren-Ibanez, A, Perez-Riba, M.
Deposit date:2015-06-15
Release date:2016-02-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.
Plos One, 10, 2015
2HYO
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BU of 2hyo by Molmil
Crystal structure of Rv0805 N97A mutant
Descriptor: FE (III) ION, MANGANESE (II) ION, Rv0805N97A
Authors:Shenoy, A.R, Capuder, M, Draskovic, P, Lamba, D, Visweswariah, S.S, Podobnik, M.
Deposit date:2006-08-07
Release date:2006-12-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis.
J.Mol.Biol., 365, 2007
6UUQ
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BU of 6uuq by Molmil
Structure of Calcineurin bound to RCAN1
Descriptor: Calcipressin-1, FE (III) ION, PHOSPHATE ION, ...
Authors:Sheftic, S, Page, R, Peti, W.
Deposit date:2019-10-31
Release date:2020-09-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.849 Å)
Cite:The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin.
Sci Adv, 6, 2020
2ZBM
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BU of 2zbm by Molmil
Crystal Structure of I115M Mutant Cold-Active Protein Tyrosine Phosphatase
Descriptor: Protein-tyrosine-phosphatase, ZINC ION
Authors:Tsuruta, H, Mikami, B, Yamamoto, C, Yamagata, H.
Deposit date:2007-10-24
Release date:2008-07-29
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase
Febs J., 275, 2008
2ZO9
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BU of 2zo9 by Molmil
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal ion preference
Descriptor: FE (II) ION, MALONATE ION, Phosphohydrolase
Authors:Jackson, C.J, Carr, P.D, Ollis, D.L.
Deposit date:2008-05-07
Release date:2008-10-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
3RL3
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BU of 3rl3 by Molmil
Rat metallophosphodiesterase MPPED2
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Podobnik, M, Dermol, U.
Deposit date:2011-04-19
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011
6WII
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BU of 6wii by Molmil
Crystal structure of the K. pneumoniae LpxH/JH-LPH-41 complex
Descriptor: 5-({[4-({4-[3-chloro-5-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)phenyl]carbamoyl}amino)-N-hydroxypentanamide, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Cochrane, C.S, Cho, J, Fenton, B.A, Zhou, P.
Deposit date:2020-04-09
Release date:2020-07-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors.
Bioorg.Chem., 102, 2020
6X1Z
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BU of 6x1z by Molmil
Mre11 dimer in complex with small molecule modulator PFMJ
Descriptor: (5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ...
Authors:Arvai, A.S, Moiani, D, Tainer, J.A.
Deposit date:2020-05-19
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
4J6O
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BU of 4j6o by Molmil
Crystal Structure of the Phosphatase Domain of C. thermocellum (Bacterial) PnkP
Descriptor: CITRIC ACID, GLYCEROL, MANGANESE (II) ION, ...
Authors:Wang, L, Smith, P, Shuman, S.
Deposit date:2013-02-11
Release date:2013-04-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system.
Nucleic Acids Res., 41, 2013
3RL4
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BU of 3rl4 by Molmil
Rat metallophosphodiesterase MPPED2 G252H Mutant
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Podobnik, M, Dermol, U.
Deposit date:2011-04-19
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011
3D03
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BU of 3d03 by Molmil
1.9A structure of Glycerophoshphodiesterase (GpdQ) from Enterobacter aerogenes
Descriptor: COBALT (II) ION, Phosphohydrolase
Authors:Hadler, K.S, Tanifum, E, Yip, S.H.-C, Miti, N, Guddat, L.W, Jackson, C.J, Gahan, L.R, Carr, P.D, Nguyen, K, Ollis, D.L, Hengge, A.C, Larrabee, J.A, Schenk, G.
Deposit date:2008-04-30
Release date:2008-10-14
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes.
J.Am.Chem.Soc., 130, 2008
2ZOA
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BU of 2zoa by Molmil
Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) COLLECTED AT 1.280 ANGSTROM
Descriptor: FE (II) ION, MALONATE ION, Phosphohydrolase
Authors:Ollis, D.L, Jackson, C.J, Carr, P.D.
Deposit date:2008-05-07
Release date:2008-10-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
6X1Y
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BU of 6x1y by Molmil
Mre11 dimer in complex with small molecule modulator PFMI
Descriptor: (5Z)-5-[(3-methoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nuclease SbcCD subunit D
Authors:Arvai, A.S, Moiani, D, Tainer, J.A.
Deposit date:2020-05-19
Release date:2020-06-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.
Prog.Biophys.Mol.Biol., 163, 2021
3AUZ
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BU of 3auz by Molmil
Crystal structure of Mre11 with manganese
Descriptor: DNA double-strand break repair protein mre11, GLYCEROL, MANGANESE (II) ION
Authors:Park, Y.B, Cho, Y.
Deposit date:2011-02-18
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.206 Å)
Cite:Crystal Structure of the Mre11-Rad50-ATP S Complex: Understanding the Interplay between Mre11 and Rad50
To be Published
3RL5
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BU of 3rl5 by Molmil
Rat metallophosphodiesterase MPPED2 H67R Mutant
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Metallophosphoesterase MPPED2, ...
Authors:Podobnik, M, Dermol, U.
Deposit date:2011-04-19
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Unique utilization of a phosphoprotein phosphatase fold by a mammalian phosphodiesterase associated with WAGR syndrome.
J.Mol.Biol., 412, 2011

221051

數據於2024-06-12公開中

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