4HZI
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1SGW
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![BU of 1sgw by Molmil](/molmil-images/mine/1sgw) | Putative ABC transporter (ATP-binding protein) from Pyrococcus furiosus Pfu-867808-001 | Descriptor: | CHLORIDE ION, SODIUM ION, putative ABC transporter | Authors: | Liu, Z.J, Tempel, W, Shah, A, Chen, L, Lee, D, Kelley, L.-L.C, Dillard, B.D, Rose, J.P, Eneh, J.C, Hopkins, R.C, Jenney Jr, F.E, Lee, H.S, Poole II, F.L, Shah, C, Sugar, F.J, Adams, M.W.W, Richardson, D.C, Richardson, J.S, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-02-24 | Release date: | 2004-08-10 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Putative ABC transporter (ATP-binding protein) from Pyrococcus furiosus Pfu-867808-001 To be Published
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1VPL
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1XMJ
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![BU of 1xmj by Molmil](/molmil-images/mine/1xmj) | Crystal structure of human deltaF508 human NBD1 domain with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | Deposit date: | 2004-10-02 | Release date: | 2004-11-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
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1XF9
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![BU of 1xf9 by Molmil](/molmil-images/mine/1xf9) | Structure of NBD1 from murine CFTR- F508S mutant | Descriptor: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | Authors: | Thibodeau, P.H, Brautigam, C.A, Machius, M, Thomas, P.J. | Deposit date: | 2004-09-14 | Release date: | 2004-12-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol., 12, 2005
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1YQT
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![BU of 1yqt by Molmil](/molmil-images/mine/1yqt) | RNase-L Inhibitor | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RNase l inhibitor | Authors: | Karcher, A, Buttner, K, Martens, B, Jansen, R.P, Hopfner, K.P. | Deposit date: | 2005-02-02 | Release date: | 2005-04-19 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structure of RLI, an essential twin cassette ABC ATPase involved in ribosome biogenesis and HIV capsid assembly. Structure, 13, 2005
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1XMI
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![BU of 1xmi by Molmil](/molmil-images/mine/1xmi) | Crystal structure of human F508A NBD1 domain with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Lewis, H.A, Zhao, X, Wang, C, Sauder, J.M, Rooney, I, Noland, B.W, Lorimer, D, Kearins, M.C, Conners, K, Condon, B, Maloney, P.C, Guggino, W.B, Hunt, J.F, Emtage, S, Structural GenomiX | Deposit date: | 2004-10-02 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Impact of the delta-F508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure J.Biol.Chem., 280, 2005
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1XFA
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![BU of 1xfa by Molmil](/molmil-images/mine/1xfa) | Structure of NBD1 from murine CFTR- F508R mutant | Descriptor: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Thibodeau, P.H, Brautigam, C.A, Machius, M, Thomas, P.J. | Deposit date: | 2004-09-14 | Release date: | 2004-12-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol., 12, 2005
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1XEF
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![BU of 1xef by Molmil](/molmil-images/mine/1xef) | Crystal structure of the ATP/Mg2+ bound composite dimer of HlyB-NBD | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Alpha-hemolysin translocation ATP-binding protein hlyB, MAGNESIUM ION | Authors: | Zaitseva, J, Jenewein, S, Holland, I.B, Schmitt, L. | Deposit date: | 2004-09-10 | Release date: | 2005-06-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | H662 is the linchpin of ATP hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB Embo J., 24, 2005
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4ZIR
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![BU of 4zir by Molmil](/molmil-images/mine/4zir) | Crystal structure of EcfAA' heterodimer bound to AMPPNP | Descriptor: | CHLORIDE ION, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | Authors: | Karpowich, N.K, Cocco, N, Song, J.M, Wang, D.N. | Deposit date: | 2015-04-28 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | ATP binding drives substrate capture in an ECF transporter by a release-and-catch mechanism. Nat.Struct.Mol.Biol., 22, 2015
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6GJQ
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![BU of 6gjq by Molmil](/molmil-images/mine/6gjq) | human NBD1 of CFTR in complex with nanobody T27 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, Nanobody T27 | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | Deposit date: | 2018-05-16 | Release date: | 2019-06-19 | Last modified: | 2019-08-21 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
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6GKD
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![BU of 6gkd by Molmil](/molmil-images/mine/6gkd) | human NBD1 of CFTR in complex with nanobodies D12 and G3a | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, GLYCEROL, ... | Authors: | Sigoillot, M, Overtus, M, Grodecka, M, Scholl, D, Garcia-Pino, A, Laeremans, T, He, L, Pardon, E, Hildebrandt, E, Urbatsch, I, Steyaert, J, Riordan, J.R, Govaerts, C. | Deposit date: | 2018-05-18 | Release date: | 2019-06-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Domain-interface dynamics of CFTR revealed by stabilizing nanobodies. Nat Commun, 10, 2019
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3GFO
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![BU of 3gfo by Molmil](/molmil-images/mine/3gfo) | Structure of cbiO1 from clostridium perfringens: Part of the ABC transporter complex cbiONQ. | Descriptor: | Cobalt import ATP-binding protein cbiO 1, SULFATE ION | Authors: | Ramagopal, U.A, Morano, C, Toro, R, Dickey, M, Do, J, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2009-02-27 | Release date: | 2009-03-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of cbiO1 from clostridium perfringens: Part of the ABC transporter complex cbiONQ To be published
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5DGX
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![BU of 5dgx by Molmil](/molmil-images/mine/5dgx) | 1.73 Angstrom resolution crystal structure of the ABC-ATPase domain (residues 357-609) of lipid A transport protein (msbA) from Francisella tularensis subsp. tularensis SCHU S4 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Lipid A export ATP-binding/permease protein MsbA | Authors: | Halavaty, A.S, Minasov, G, Dubrovska, I, Kiryukhina, O, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-08-28 | Release date: | 2015-09-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | 1.73 Angstrom resolution crystal structure of the ABC-ATPase domain (residues 357-609) of lipid A transport protein (msbA) from Francisella tularensis subsp. tularensis SCHU S4 in complex with ADP To Be Published
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2IXF
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![BU of 2ixf by Molmil](/molmil-images/mine/2ixf) | Crystal structure of the ATPase domain of TAP1 with ATP (D645Q, Q678H mutant) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, GLYCEROL, ... | Authors: | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | Deposit date: | 2006-07-08 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter. Mol.Cell, 24, 2001
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4WZ6
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![BU of 4wz6 by Molmil](/molmil-images/mine/4wz6) | Human CFTR aa389-678 (NBD1), deltaF508 with three solubilizing mutations, bound ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION | Authors: | Byrnes, L.J, Hall, J. | Deposit date: | 2014-11-18 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy. Protein Sci., 25, 2016
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2IXE
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![BU of 2ixe by Molmil](/molmil-images/mine/2ixe) | Crystal structure of the ATPase domain of TAP1 with ATP (D645N mutant) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, MAGNESIUM ION, ... | Authors: | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | Deposit date: | 2006-07-07 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter. Mol.Cell, 24, 2001
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2IXG
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![BU of 2ixg by Molmil](/molmil-images/mine/2ixg) | Crystal structure of the ATPase domain of TAP1 with ATP (S621A, G622V, D645N mutant) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ANTIGEN PEPTIDE TRANSPORTER 1, GLYCEROL | Authors: | Procko, E, Ferrin-O'Connell, I, Ng, S.-L, Gaudet, R. | Deposit date: | 2006-07-08 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Distinct Structural and Functional Properties of the ATPase Sites in an Asymmetric Abc Transporter. Mol.Cell, 24, 2001
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2IHY
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![BU of 2ihy by Molmil](/molmil-images/mine/2ihy) | Structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter | Descriptor: | ABC transporter, ATP-binding protein, SULFATE ION | Authors: | McGrath, T.E, Yu, C.S, Romanov, V, Lam, R, Dharamsi, A, Virag, C, Mansoury, K, Thambipillai, D, Richards, D, Guthrie, J, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | Deposit date: | 2006-09-27 | Release date: | 2007-09-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the Staphylococcus aureus putative ATPase subunit of an ATP-binding cassette (ABC) transporter To be Published
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2YZ2
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![BU of 2yz2 by Molmil](/molmil-images/mine/2yz2) | Crystal structure of the ABC transporter in the cobalt transport system | Descriptor: | Putative ABC transporter ATP-binding protein TM_0222 | Authors: | Ethayathullah, A.S, Bessho, Y, Padmanabhan, B, Singh, T.P, Kaur, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-05-02 | Release date: | 2007-11-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the ABC transporter in the cobalt transport system To be Published
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3B5J
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![BU of 3b5j by Molmil](/molmil-images/mine/3b5j) | Crystal Structures of the S504A Mutant of an Isolated ABC-ATPase in Complex with TNP-ADP | Descriptor: | 2',3'-O-[(1R,6R)-2,4,6-trinitrocyclohexa-2,4-diene-1,1-diyl]adenosine 5'-(trihydrogen diphosphate), Alpha-hemolysin translocation ATP-binding protein hlyB | Authors: | Oswald, C, Jenewein, S, Smits, S.H.J, Holland, I.B, Schmitt, L. | Deposit date: | 2007-10-26 | Release date: | 2008-01-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Water-mediated protein-fluorophore interactions modulate the affinity of an ABC-ATPase/TNP-ADP complex J.Struct.Biol., 162, 2008
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3C41
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![BU of 3c41 by Molmil](/molmil-images/mine/3c41) | ABC protein ArtP in complex with AMP-PNP/Mg2+ | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | Deposit date: | 2008-01-29 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region To be Published
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3C4J
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![BU of 3c4j by Molmil](/molmil-images/mine/3c4j) | ABC protein ArtP in complex with ATP-gamma-S | Descriptor: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | Deposit date: | 2008-01-30 | Release date: | 2009-02-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region To be Published
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1MT0
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![BU of 1mt0 by Molmil](/molmil-images/mine/1mt0) | ATP-binding domain of hemolysin B from Escherichia coli | Descriptor: | Hemolysin secretion ATP-binding protein, SULFATE ION | Authors: | Schmitt, L, Benabdelhak, H, Blight, M.A, Holland, I.B, Stubbs, M.T. | Deposit date: | 2002-09-20 | Release date: | 2003-06-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of the nucleotide binding domain of the
ABC-transporter hemolysin B: identification of a variable region
within ABC helical domains J.Mol.Biol., 330, 2003
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3SI7
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![BU of 3si7 by Molmil](/molmil-images/mine/3si7) | The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant | Descriptor: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | Authors: | Brautigam, C.A, Caspa, E, Thomas, P.J. | Deposit date: | 2011-06-17 | Release date: | 2012-02-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Requirements for efficient correction of DeltaF508 CFTR revealed by analyses of evolved sequences Cell(Cambridge,Mass.), 148, 2012
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