8IGF
 
 | | Crystal Structure of Human Carbonic Anhydrase II In-complex with 4-Acetylphenylboronic acid at 2.6 A Resolution | | Descriptor: | (4-ethanoylphenyl)boronic acid, Carbonic anhydrase 2, GLYCEROL, ... | | Authors: | Rasheed, S, Huda, N, Fisher, S.Z, Falke, S, Gul, S, Ahmad, M.S, Choudhary, M.I. | | Deposit date: | 2023-02-20 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II.
Int.J.Biol.Macromol., 267, 2024
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8DE8
 | | Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPA mixed micelles | | Descriptor: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, POTASSIUM ION, Potassium channel, ... | | Authors: | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | | Deposit date: | 2022-06-20 | | Release date: | 2023-03-08 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.
Nat Commun, 14, 2023
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8R49
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8R6K
 | | Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a phenyltriazine ligand | | Descriptor: | 6-methyl-~{N}-[(5-methylfuran-2-yl)methyl]-3-(4-methylphenyl)-1,2,4-triazin-5-amine, Candida glabrata strain CBS138 chromosome C complete sequence, PHOSPHATE ION, ... | | Authors: | Petosa, C, Wei, K, McKenna, C.E, Govin, J. | | Deposit date: | 2023-11-22 | | Release date: | 2024-10-30 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential.
Adv Sci, 12, 2025
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6WK8
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9B26
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9B2Z
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7REK
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6NRP
 | | Putative short-chain dehydrogenase/reductase (SDR) from Acinetobacter baumannii | | Descriptor: | 3-oxoacyl-ACP reductase FabG | | Authors: | Cross, E.M, Smith, K.M, Shaw, K.I, Aragao, D, Forwood, J.K. | | Deposit date: | 2019-01-23 | | Release date: | 2019-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Insights into Acinetobacter baumannii fatty acid synthesis 3-oxoacyl-ACP reductases.
Sci Rep, 11, 2021
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9LTK
 | | Crystal structur of Lpg1618(R215F) from Legionella pneumophila | | Descriptor: | Beta-lactamase, GLYCEROL, SULFATE ION | | Authors: | Liu, T, Gao, J, Ge, H. | | Deposit date: | 2025-02-06 | | Release date: | 2025-06-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and molecular characterization of AmpS, a class D beta-lactamase from Legionella pneumophila.
Int.J.Biol.Macromol., 312, 2025
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6PU0
 | | Pigeon Cryptochrome4 bound to flavin adenine dinucleotide | | Descriptor: | 1,2-ETHANEDIOL, Cryptochrome-1, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Zoltowski, B.D, Chelliah, Y, Wickramaratne, A.C, Jarocha, L, Karki, N, Mouritsen, H, Hore, P.J, Hibbs, R.E, Green, C.B, Takahashi, J.S. | | Deposit date: | 2019-07-16 | | Release date: | 2019-09-04 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.8979 Å) | | Cite: | Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5IMP
 | | Crystal structure of N299A Aspergillus terreus aristolochene synthase complexed with (1S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)decahydroquinolizin-5-ium | | Descriptor: | (1S,5S,8S,9aR)-1,9a-dimethyl-8-(prop-1-en-2-yl)octahydro-2H-quinolizinium, Aristolochene synthase, GLYCEROL, ... | | Authors: | Chen, M, Christianson, D.W. | | Deposit date: | 2016-03-06 | | Release date: | 2016-05-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.038 Å) | | Cite: | Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase.
Biochemistry, 55, 2016
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8RAL
 | | CL3E peptide bound to the I-Ab murine MHC class II receptor | | Descriptor: | 1,2-ETHANEDIOL, CL3E peptide, H-2 class II histocompatibility antigen, ... | | Authors: | Erausquin, E, Urdiciain, A, Serra, P, Santamaria, P, Lopez-Sagaseta, J. | | Deposit date: | 2023-12-01 | | Release date: | 2024-11-06 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | CL3E peptide bound to the I-Ab murine MHC class II receptor
To be published
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9GST
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9GSW
 | | Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with iminosugar compound 4d | | Descriptor: | (2~{R},3~{R},4~{R},5~{S})-2-(hydroxymethyl)-2-(2-trimethylsilylethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Sulzenbacher, G, Roig-Zamboni, V, Moracci, M, Parenti, G, Py, S. | | Deposit date: | 2024-09-16 | | Release date: | 2025-09-24 | | Last modified: | 2025-10-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | C -Branched Iminosugars as Selective Pharmacological Chaperones of Lysosomal alpha-Glucosidase for the Treatment of Pompe Disease.
J.Med.Chem., 68, 2025
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7RJ1
 | | Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chorismate mutase, ... | | Authors: | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-20 | | Release date: | 2021-07-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Crystal structure of Aro7p chorismate mutase from Candida albicans, complex with L-Trp
To Be Published
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7RIN
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6PWC
 | | A complex structure of arrestin-2 bound to neurotensin receptor 1 | | Descriptor: | Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ... | | Authors: | Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E. | | Deposit date: | 2019-07-22 | | Release date: | 2019-12-04 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Cell Res., 29, 2019
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8D5T
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8D69
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9GSV
 | | Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with iminosugar compound 4c | | Descriptor: | (2~{R},3~{R},4~{R},5~{S})-2-(hydroxymethyl)-2-(2-phenylethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Sulzenbacher, G, Roig-Zamboni, V, Moracci, M, Parenti, G, Py, S. | | Deposit date: | 2024-09-16 | | Release date: | 2025-09-24 | | Last modified: | 2025-10-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | C -Branched Iminosugars as Selective Pharmacological Chaperones of Lysosomal alpha-Glucosidase for the Treatment of Pompe Disease.
J.Med.Chem., 68, 2025
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7RNV
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8D7L
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7RNS
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8D77
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