2NT4
 
 | | Receiver domain from Myxococcus xanthus social motility protein FrzS (H92F mutant) | | Descriptor: | CHLORIDE ION, Response regulator homolog | | Authors: | Echols, N, Fraser, J, Weisfield, S, Merlie, J, Zusman, D, Alber, T. | | Deposit date: | 2006-11-06 | | Release date: | 2007-03-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.02 Å) | | Cite: | An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.
Mol.Microbiol., 65, 2007
|
|
2NT6
 | | Crystal structure of pectin methylesterase D178A mutant in complex with hexasaccharide III | | Descriptor: | Pectinesterase A, methyl alpha-D-galactopyranuronate-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-methyl alpha-D-galactopyranuronate | | Authors: | Fries, M, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W. | | Deposit date: | 2006-11-07 | | Release date: | 2007-09-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular basis of the activity of the phytopathogen pectin methylesterase.
Embo J., 26, 2007
|
|
2NT7
 | | Crystal structure of PTP1B-inhibitor complex | | Descriptor: | Tyrosine-protein phosphatase non-receptor type 1, {[5-(3-{[1-(BENZYLSULFONYL)PIPERIDIN-4-YL]AMINO}PHENYL)-4-BROMO-2-(2H-TETRAZOL-5-YL)-3-THIENYL]OXY}ACETIC ACID | | Authors: | Xu, W, Follows, B. | | Deposit date: | 2006-11-07 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Probing acid replacements of thiophene PTP1B inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
2NT8
 | | ATP bound at the active site of a PduO type ATP:co(I)rrinoid adenosyltransferase from Lactobacillus reuteri | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cobalamin adenosyltransferase, GLYCEROL, ... | | Authors: | St-Maurice, M, Mera, P.E, Taranto, M.P, Sesma, F, Escalante-Semerena, J.C, Rayment, I. | | Deposit date: | 2006-11-07 | | Release date: | 2006-11-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Structural characterization of the active site of the PduO-type ATP:Co(I)rrinoid adenosyltransferase from Lactobacillus reuteri.
J.Biol.Chem., 282, 2007
|
|
2NT9
 | | Crystal structure of pectin methylesterase D178A mutant in complex with hexasaccharide IV | | Descriptor: | Pectinesterase A, alpha-D-galactopyranuronic acid-(1-4)-methyl alpha-D-galactopyranuronate-(1-4)-methyl alpha-D-galactopyranuronate-(1-4)-methyl alpha-D-galactopyranuronate-(1-4)-methyl alpha-D-galactopyranuronate-(1-4)-alpha-D-galactopyranuronic acid | | Authors: | Fries, M, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W. | | Deposit date: | 2006-11-07 | | Release date: | 2007-09-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular basis of the activity of the phytopathogen pectin methylesterase.
Embo J., 26, 2007
|
|
2NTA
 | | Crystal Structure of PTP1B-inhibitor Complex | | Descriptor: | 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE, Tyrosine-protein phosphatase non-receptor type 1 | | Authors: | Xu, W, Follows, B. | | Deposit date: | 2006-11-07 | | Release date: | 2007-04-17 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Probing acid replacements of thiophene PTP1B inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
2NTB
 | | Crystal structure of pectin methylesterase in complex with hexasaccharide V | | Descriptor: | Pectinesterase A, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | | Authors: | Fries, M, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W. | | Deposit date: | 2006-11-07 | | Release date: | 2007-09-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular basis of the activity of the phytopathogen pectin methylesterase.
Embo J., 26, 2007
|
|
2NTC
 | |
2NTD
 | |
2NTE
 | | Crystal Structure of the BARD1 BRCT Domains | | Descriptor: | 1,2-ETHANEDIOL, BRCA1-associated RING domain protein 1, CHLORIDE ION, ... | | Authors: | Birrane, G, Varma, A.K, Soni, A, Ladias, J.A.A. | | Deposit date: | 2006-11-07 | | Release date: | 2007-06-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of the BARD1 BRCT domains.
Biochemistry, 46, 2007
|
|
2NTF
 | |
2NTG
 | | Structure of Spin-labeled T4 Lysozyme Mutant T115R7 | | Descriptor: | BETA-MERCAPTOETHANOL, Lysozyme, S-[(4-bromo-1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | Authors: | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | | Deposit date: | 2006-11-07 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
|
|
2NTH
 | | Structure of Spin-labeled T4 Lysozyme Mutant L118R1 | | Descriptor: | Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | Authors: | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | | Deposit date: | 2006-11-07 | | Release date: | 2007-06-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
|
|
2NTI
 | | Crystal structure of PCNA123 heterotrimer. | | Descriptor: | 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ... | | Authors: | Hlinkova, V, Ling, H. | | Deposit date: | 2006-11-07 | | Release date: | 2007-12-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
|
|
2NTJ
 | | Mycobacterium tuberculosis InhA bound with PTH-NAD adduct | | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH, {(2R,3S,4R,5R)-5-[(4S)-3-(AMINOCARBONYL)-4-(2-PROPYLISONICOTINOYL)PYRIDIN-1(4H)-YL]-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL}M ETHYL [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | | Authors: | Wang, F, Sacchettini, J.C. | | Deposit date: | 2006-11-07 | | Release date: | 2007-01-30 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanism of thioamide drug action against tuberculosis and leprosy.
J.Exp.Med., 204, 2007
|
|
2NTK
 | | Crystal structure of PurO/IMP from Methanothermobacter thermoautotrophicus | | Descriptor: | IMP cyclohydrolase, INOSINIC ACID | | Authors: | Kang, Y.N, Tran, A, White, R.H, Ealick, S.E. | | Deposit date: | 2006-11-07 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Biochemistry, 46, 2007
|
|
2NTL
 | | Crystal structure of PurO/AICAR from Methanothermobacter thermoautotrophicus | | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, IMP cyclohydrolase | | Authors: | Kang, Y.N, Tran, A, White, R.H, Ealick, S.E. | | Deposit date: | 2006-11-07 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Biochemistry, 46, 2007
|
|
2NTM
 | |
2NTN
 | | Crystal structure of MabA-C60V/G139A/S144L | | Descriptor: | 3-oxoacyl-[acyl-carrier-protein] reductase | | Authors: | Poncet-Montange, G, Ducasse-Cabanot, S, Quemard, A, Labesse, G, Cohen-Gonsaud, M. | | Deposit date: | 2006-11-08 | | Release date: | 2006-11-21 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
|
|
2NTO
 | | Structure of the Glutathione Transferase from Ochrobactrum anthropi in complex with glutathione | | Descriptor: | GLUTATHIONE, SULFATE ION, glutathione S-transferase | | Authors: | Federici, L, Bonivento, D, Di Matteo, A, Allocati, N. | | Deposit date: | 2006-11-08 | | Release date: | 2007-09-25 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | Role of Ser11 in the stabilization of the structure of Ochrobactrum anthropi glutathione transferase
Biochem.J., 403, 2007
|
|
2NTP
 | | Crystal structure of pectin methylesterase in complex with hexasaccharide VI | | Descriptor: | Pectinesterase A, methyl alpha-D-galactopyranuronate-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid, methyl beta-D-galactopyranuronate-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | | Authors: | Fries, M, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W. | | Deposit date: | 2006-11-08 | | Release date: | 2007-09-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Molecular basis of the activity of the phytopathogen pectin methylesterase.
Embo J., 26, 2007
|
|
2NTQ
 | | Crystal structure of pectin methylesterase in complex with hexasaccharide VII | | Descriptor: | Pectinesterase A, methyl alpha-D-galactopyranuronate-(1-4)-methyl alpha-D-galactopyranuronate-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | | Authors: | Fries, M, Brocklehurst, K, Shevchik, V.E, Pickersgill, R.W. | | Deposit date: | 2006-11-08 | | Release date: | 2007-09-18 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular basis of the activity of the phytopathogen pectin methylesterase.
Embo J., 26, 2007
|
|
2NTR
 | | Crystal structure of Human Bace-1 bound to inhibitor | | Descriptor: | (2R)-2-(5-{3-chloro-6-((2-methoxyethyl){[(1S,2S)-2-methylcyclopropyl]methyl}amino)-2-[methyl(methylsulfonyl)amino]pyrid in-4-yl}-1,3,4-oxadiazol-2-yl)-1-phenylpropan-2-amine, Beta-secretase 1 | | Authors: | Munshi, S. | | Deposit date: | 2006-11-08 | | Release date: | 2007-11-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Beta-secretase (BACE-1) inhibitors: accounting for 10s loop flexibility using rigid active sites.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
2NTS
 | | Crystal Structure of SEK-hVb5.1 | | Descriptor: | Staphylococcal enterotoxin K, TRBC1 protein | | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | | Deposit date: | 2006-11-08 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
|
|
2NTT
 | | Crystal Structure of SEK | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Staphylococcal enterotoxin K | | Authors: | Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J. | | Deposit date: | 2006-11-08 | | Release date: | 2007-06-26 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.561 Å) | | Cite: | A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
|
|
