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1FXF	CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + PHOSPHATE IONS) Descriptor: 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ... Authors: Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J. Deposit date: 2000-09-25 Release date: 2001-09-25 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding. Biochemistry, 40, 2001
6PWH	Cystal structure of Myotoxin II from Bothrops moojeni co-crystallized with Varespladib (LY315920) Descriptor: ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid, Basic phospholipase A2 homolog 2, DIMETHYL SULFOXIDE Authors: Salvador, G.H.M, Fontes, M.R.M. Deposit date: 2019-07-23 Release date: 2019-12-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.749 Å) Cite: Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920). Sci Rep, 9, 2019
7N6D	HLA peptide complex Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... Authors: Chaurasia, P, Petersen, J, Rossjohn, J. Deposit date: 2021-06-08 Release date: 2021-07-28 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
4DRW	Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide Descriptor: Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein Authors: Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S. Deposit date: 2012-02-17 Release date: 2012-10-24 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structure of an asymmetric ternary protein complex provides insight for membrane interaction. Structure, 20, 2012
8DWM	Host-guest complex of bleomycin A2 fully bound to CTTAGTTATAACTAAG Descriptor: BLEOMYCIN A2, COBALT (III) ION, DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), ... Authors: Georgiadis, M.M. Deposit date: 2022-08-01 Release date: 2023-01-11 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.99 Å) Cite: Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites. Bioorg.Med.Chem., 77, 2023
2WG9	Structure of Oryza Sativa (Rice) PLA2, complex with octanoic acid Descriptor: CALCIUM ION, OCTANOIC ACID (CAPRYLIC ACID), PUTATIVE PHOSPHOLIPASE A2, ... Authors: Guy, J.E, Stahl, U, Lindqvist, Y. Deposit date: 2009-04-16 Release date: 2009-06-02 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
1GP7	Acidic Phospholipase A2 from venom of Ophiophagus Hannah Descriptor: CALCIUM ION, PHOSPHOLIPASE A2 Authors: Zhang, H, Lin, Z. Deposit date: 2001-10-30 Release date: 2002-10-31 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of a Cardiotoxic Phospholipase A(2) from Ophiophagus Hannah with the "Pancreatic Loop" J.Struct.Biol., 138, 2002
2WG8	Structure of Oryza Sativa (Rice) PLA2, orthorhombic crystal form Descriptor: CALCIUM ION, PUTATIVE PHOSPHOLIPASE A2, SODIUM ION Authors: Guy, J.E, Stahl, U, Lindqvist, Y. Deposit date: 2009-04-16 Release date: 2009-06-02 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
2WG7	Structure of Oryza Sativa (Rice) PLA2 Descriptor: CALCIUM ION, PUTATIVE PHOSPHOLIPASE A2, SODIUM ION Authors: Guy, J.E, Stahl, U, Lindqvist, Y. Deposit date: 2009-04-16 Release date: 2009-06-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of a Class Xib Phospholipase A2 (Pla2): Rice (Oryza Sativa) Isoform-2 Pla2 and an Octanoate Complex. J.Biol.Chem., 284, 2009
5YD6	Crystal structure of PG-bound Nurr1-LBD Descriptor: (~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic acid, MAGNESIUM ION, Nuclear receptor subfamily 4 group A member 2 Authors: Sreekanth, R, Yoon, H.S. Deposit date: 2017-09-11 Release date: 2019-03-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structure of Nurr1 bound to cyclopentenone prostaglandin A2 and its mechanism of action in ameliorating dopaminergic neurodegeneration in Drosophila To Be Published
5YBQ	Fe(II)/(alpha)ketoglutarate-dependent dioxygenase PrhA-V150L/A232S in complex with preaustinoid A2 Descriptor: 2-OXOGLUTARIC ACID, FE (III) ION, PrhA, ... Authors: Nakashima, Y, Senda, M. Deposit date: 2017-09-05 Release date: 2018-01-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis. Nat Commun, 9, 2018
3HHV	The crystal structure of the Thioredoxin A2 from Sulfolobus solfataricus Descriptor: Thioredoxin (TrxA-2) Authors: Ruggiero, A, Masullo, M, Ruocco, M.R, Arcari, P, Zagari, A, Vitagliano, L. Deposit date: 2009-05-18 Release date: 2009-10-27 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.83 Å) Cite: The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability Proteins, 77, 2009
5E6I	Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... Authors: Gao, M, Mariuzza, R. Deposit date: 2015-10-09 Release date: 2016-10-19 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (4 Å) Cite: Crystal structure of TCR PF8 in complex with flu MP(58-66) epitope presented by HLA-A2 To Be Published
9C4A	Cryo-EM Structure of EV-D68 Vaccine Candidate - A2 Subclade Virus-like Particle Descriptor: VP0, VP1, VP3 Authors: Cheng, J, Krug, P.W, Lei, H, Moss, D.L, Huang, R, Lang, Z.C, Morton, A.J, Shen, C, Pierson, T.C, Zhou, T, Ruckwardt, T.J, Kwong, P.D. Deposit date: 2024-06-03 Release date: 2025-05-21 Method: ELECTRON MICROSCOPY (2.43 Å) Cite: Cryo-EM Structure of EV-D68 Vaccine Candidate - A2 Subclade Virus-like Particle To Be Published
5EUO	PF6-M1-HLA-A2 Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... Authors: Yang, X. Deposit date: 2015-11-18 Release date: 2016-11-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of PF6-M1-HLA-A2 complex To Be Published
4FA0	Crystal structure of human AdPLA to 2.65 A resolution Descriptor: Group XVI phospholipase A1/A2 Authors: Lovell, S, Battaile, K.P, Addington, L, Zhang, N, Rao, J.L.U.M, Moise, A.R. Deposit date: 2012-05-21 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure/Function relationships of adipose phospholipase A2 containing a cys-his-his catalytic triad. J.Biol.Chem., 287, 2012
5NHT	human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 Descriptor: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ... Authors: Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D. Deposit date: 2017-03-22 Release date: 2018-05-16 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: human 199.54-16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 To Be Published
3AL8	Plexin A2 / Semaphorin 6A complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2, ... Authors: Nogi, T, Yasui, N, Mihara, E, Takagi, J. Deposit date: 2010-07-28 Release date: 2010-10-06 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural basis for semaphorin signalling through the plexin receptor. Nature, 467, 2010
3AL9	Mouse Plexin A2 extracellular domain Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2 Authors: Nogi, T, Yasui, N, Mihara, E, Takagi, J. Deposit date: 2010-07-28 Release date: 2010-10-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural basis for semaphorin signalling through the plexin receptor. Nature, 467, 2010
2ZW7	Crystal structure of bleomycin N-acetyltransferase complexed with bleomycin A2 and coenzyme A Descriptor: BLEOMYCIN A2, Bleomycin acetyltransferase, COENZYME A Authors: Oda, K, Matoba, Y, Sugiyama, M. Deposit date: 2008-12-01 Release date: 2009-11-03 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Catalytic mechanism of bleomycin N-acetyltransferase proposed on the basis of its crystal structure. J.Biol.Chem., 285, 2010
7AYX	Structure of the cytochrome P450 AryC from Streptomyces roseosporus NRRL 15998 Descriptor: Cytochrome P450 113A1, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Schneider, S, Schaefers, F, Gulder, T.A.M. Deposit date: 2020-11-13 Release date: 2021-10-27 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Carrier Protein-Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC. Chemistry, 28, 2022
5NQK	human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... Authors: Exertier, C, Reiser, J.-B, Lantez, V, Chouquet, A, Bonneville, M, Saulquin, X, Housset, D. Deposit date: 2017-04-20 Release date: 2018-05-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.25 Å) Cite: human 199.16 TCR in complex with Melan-A/MART-1 (26-35) peptide and HLA-A2 To Be Published
7D5S	Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S12, ... Authors: Du, Y, Zhang, J, An, W, Ye, K. Deposit date: 2020-09-28 Release date: 2021-10-06 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (4.6 Å) Cite: Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2) To Be Published
4HX1	Structure of HLA-A68 complexed with a tumor antigen derived peptide Descriptor: 9-mer peptide from Tyrosinase-related protein-2, Beta-2-microglobulin, GLYCEROL, ... Authors: Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. Deposit date: 2012-11-09 Release date: 2013-10-02 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.802 Å) Cite: Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013
4I48	Structure of HLA-A68 complexed with an HIV Env derived peptide Descriptor: 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... Authors: Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. Deposit date: 2012-11-27 Release date: 2013-10-02 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.799 Å) Cite: Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes Mol.Immunol., 55, 2013

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