2J4H
| Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme | Descriptor: | DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-08-31 | Release date: | 2007-08-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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2J4I
| CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | Descriptor: | 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)-, ... | Authors: | Young, R.J, Campbell, M, Borthwick, A.D, Brown, D, Chan, C, Convery, M.A, Crowe, M.C, Dayal, S, Diallo, H, Kelly, H.A, Paul King, N, Kleanthous, S, Kurtis, C.L, Mason, A.M, Mordaunt, J.E, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Smith, P.W, Watson, N.S, Weston, H.E, Zhou, P. | Deposit date: | 2006-08-31 | Release date: | 2006-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs. Bioorg.Med.Chem.Lett., 16, 2006
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2J4J
| Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP and AMPPCP to 2.1 Angstrom resolution | Descriptor: | COBALT (II) ION, MAGNESIUM ION, P1-(5'-ADENOSINE)P4-(5'-URIDINE)-BETA,GAMMA-METHYLENE TETRAPHOSPHATE, ... | Authors: | Jensen, K.S, Johansson, E, Jensen, K.F. | Deposit date: | 2006-09-01 | Release date: | 2007-02-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
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2J4K
| Crystal structure of uridylate kinase from Sulfolobus solfataricus in complex with UMP to 2.2 Angstrom resolution | Descriptor: | CADMIUM ION, MAGNESIUM ION, URIDINE-5'-MONOPHOSPHATE, ... | Authors: | Jensen, K.S, Johansson, E, Jensen, K.F. | Deposit date: | 2006-09-01 | Release date: | 2007-02-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and Enzymatic Investigation of the Sulfolobus Solfataricus Uridylate Kinase Shows Competitive Utp Inhibition and the Lack of GTP Stimulation Biochemistry, 46, 2007
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2J4L
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2J4M
| Double dockerin from Piromyces equi Cel45A | Descriptor: | ENDOGLUCANASE 45A | Authors: | Nagy, T, Tunnicliffe, R.B, Higgins, L.D, Walters, C, Gilbert, H.J, Williamson, M.P. | Deposit date: | 2006-09-01 | Release date: | 2007-09-25 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Characterization of a Double Dockerin from the Cellulosome of the Anaerobic Fungus Piromyces Equi. J.Mol.Biol., 373, 2007
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2J4N
| Double dockerin from Piromyces equi Cel45A | Descriptor: | ENDOGLUCANASE 45A | Authors: | Nagy, T, Tunnicliffe, R.B, Higgins, L.D, Walters, C, Gilbert, H.J, Williamson, M.P. | Deposit date: | 2006-09-01 | Release date: | 2007-09-25 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Characterization of a Double Dockerin from the Cellulosome of the Anaerobic Fungus Piromyces Equi. J.Mol.Biol., 373, 2007
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2J4O
| Structure of TAB1 | Descriptor: | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 1 | Authors: | van Aalten, D. | Deposit date: | 2006-09-01 | Release date: | 2006-09-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Tak1-Binding Protein 1 is a Pseudophosphatase. Biochem.J., 399, 2006
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2J4Q
| Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP | Descriptor: | DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M. | Deposit date: | 2006-09-05 | Release date: | 2007-08-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme FEBS J., 274, 2007
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2J4R
| Structural Study of the Aquifex aeolicus PPX-GPPA enzyme | Descriptor: | EXOPOLYPHOSPHATASE, GUANOSINE-5',3'-TETRAPHOSPHATE | Authors: | Kristensen, O. | Deposit date: | 2006-09-05 | Release date: | 2007-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structure of the Ppx/Gppa Phosphatase from Aquifex Aeolicus in Complex with the Alarmone Ppgpp J.Mol.Biol., 375, 2008
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2J4S
| P450 BM3 heme domain in complex with DMSO | Descriptor: | BIFUNCTIONAL P-450:NADPH-P450 REDUCTASE, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Kuper, J, Tuck-Seng, W, Roccatano, D, Wilmanns, M, Schwaneberg, U. | Deposit date: | 2006-09-05 | Release date: | 2007-05-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3. J.Am.Chem.Soc., 129, 2007
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2J4T
| Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein | Descriptor: | ANGIOGENIN-4 | Authors: | Crabtree, B, Holloway, D.E, Baker, M.D, Acharya, K.R, Subramanian, V. | Deposit date: | 2006-09-05 | Release date: | 2007-02-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Biological and Structural Features of Murine Angiogenin-4, an Angiogenic Protein Biochemistry, 46, 2007
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2J4U
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2J4W
| Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex | Descriptor: | APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 | Authors: | Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | Deposit date: | 2006-09-07 | Release date: | 2007-01-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation. J.Mol.Biol., 366, 2007
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2J4X
| Streptococcus dysgalactiae-derived mitogen (SDM) | Descriptor: | GLYCEROL, MITOGEN, ZINC ION | Authors: | Saarinen, S, Kato, H, Uchiyama, T, Miyoshi-Akiyama, T, Papageorgiou, A.C. | Deposit date: | 2006-09-07 | Release date: | 2007-09-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of Streptococcus Dysgalactiae-Derived Mitogen Reveals a Zinc-Binding Site and Alterations in Tcr Binding. J.Mol.Biol., 373, 2007
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2J4Y
| Crystal structure of a rhodopsin stabilizing mutant expressed in mammalian cells | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RETINAL, RHODOPSIN | Authors: | Standfuss, J, Xie, G, Edwards, P.C, Burghammer, M, Oprian, D.D, Schertler, G.F.X. | Deposit date: | 2006-09-07 | Release date: | 2007-09-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal Structure of a Thermally Stable Rhodopsin Mutant. J.Mol.Biol., 372, 2007
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2J4Z
| Structure of Aurora-2 in complex with PHA-680626 | Descriptor: | 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC, SERINE THREONINE-PROTEIN KINASE 6 | Authors: | Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P. | Deposit date: | 2006-09-08 | Release date: | 2006-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile. J. Med. Chem., 49, 2006
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2J50
| Structure of Aurora-2 in complex with PHA-739358 | Descriptor: | N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6, SULFATE ION | Authors: | Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P. | Deposit date: | 2006-09-08 | Release date: | 2006-11-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile. J.Med.Chem., 49, 2006
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2J51
| Crystal structure of Human STE20-like kinase bound to 5-Amino-3-((4-(aminosulfonyl)phenyl)amino) -N-(2,6-difluorophenyl)-1H-1,2,4-triazole- 1-carbothioamide | Descriptor: | 1,2-ETHANEDIOL, 5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE, STE20-LIKE SERINE/THREONINE-PROTEIN KINASE, ... | Authors: | Pike, A.C.W, Rellos, P, Fedorov, O, Keates, T, Salah, E, Savitsky, P, Papagrigoriou, E, Turnbull, A.P, Debreczeni, J.E, von Delft, F, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S. | Deposit date: | 2006-09-08 | Release date: | 2006-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites. Embo J., 27, 2008
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2J52
| Solution Structure of GB1 domain Protein G and low and high pressure. | Descriptor: | IMMUNOGLOBULIN G-BINDING PROTEIN G | Authors: | Wilton, D.J, Tunnicliffe, R.B, Kamatari, Y.O, Akasaka, K, Williamson, M.P. | Deposit date: | 2006-09-11 | Release date: | 2007-09-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Pressure-Induced Changes in the Solution Structure of the Gb1 Domain of Protein G. Proteins, 71, 2008
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2J53
| Solution Structure of GB1 domain Protein G and low and high pressure. | Descriptor: | IMMUNOGLOBULIN G-BINDING PROTEIN G | Authors: | Wilton, D.J, Tunnicliffe, R.B, Kamatari, Y.O, Akasaka, K, Williamson, M.P. | Deposit date: | 2006-09-11 | Release date: | 2007-09-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Pressure-Induced Changes in the Solution Structure of the Gb1 Domain of Protein G. Proteins, 71, 2008
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2J55
| X-ray reduced Paraccocus denitrificans methylamine dehydrogenase O- quinone in complex with amicyanin. | Descriptor: | AMICYANIN, COPPER (II) ION, GLYCEROL, ... | Authors: | Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M. | Deposit date: | 2006-09-12 | Release date: | 2007-01-23 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry. J.Synchrotron Radiat., 14, 2007
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2J56
| X-ray reduced Paraccocus denitrificans methylamine dehydrogenase N- semiquinone in complex with amicyanin. | Descriptor: | AMICYANIN, COPPER (II) ION, GLYCEROL, ... | Authors: | Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M. | Deposit date: | 2006-09-12 | Release date: | 2007-01-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry. J.Synchrotron Radiat., 14, 2007
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2J57
| X-ray reduced Paraccocus denitrificans methylamine dehydrogenase N- quinol in complex with amicyanin. | Descriptor: | AMICYANIN, COPPER (II) ION, METHYLAMINE DEHYDROGENASE HEAVY CHAIN, ... | Authors: | Pearson, A.R, Pahl, R, Davidson, V.L, Wilmot, C.M. | Deposit date: | 2006-09-12 | Release date: | 2007-01-23 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Tracking X-Ray-Derived Redox Changes in Crystals of a Methylamine Dehydrogenase/Amicyanin Complex Using Single-Crystal Uv/Vis Microspectrophotometry. J.Synchrotron Radiat., 14, 2007
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2J58
| The structure of Wza | Descriptor: | HEXANE, N-OCTANE, OUTER MEMBRANE LIPOPROTEIN WZA, ... | Authors: | Dong, C, Naismith, J.H. | Deposit date: | 2006-09-12 | Release date: | 2006-11-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Wza the Translocon for E. Coli Capsular Polysaccharides Defines a New Class of Membrane Protein. Nature, 444, 2006
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