2Q1E
 
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2PTV
 | | Structure of NK cell receptor ligand CD48 | | Descriptor: | CD48 antigen | | Authors: | Deng, L, Velikovsky, C.A, Mariuzza, R.A. | | Deposit date: | 2007-05-08 | | Release date: | 2007-11-20 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
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2Q87
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2J1K
 | | CAV-2 fibre head in complex with CAR D1 | | Descriptor: | COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | | Deposit date: | 2006-08-14 | | Release date: | 2006-09-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
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2ICC
 | | Extracellular Domain of CRIg | | Descriptor: | V-set and immunoglobulin domain-containing protein 4 | | Authors: | Wiesmann, C. | | Deposit date: | 2006-09-12 | | Release date: | 2006-11-07 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature, 444, 2006
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1J05
 | | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment | | Descriptor: | GLYCEROL, PHOSPHATE ION, anti-CEA mAb T84.66, ... | | Authors: | Kondo, H, Nishimura, Y, Shiroishi, M, Asano, R, Noro, N, Tsumoto, K, Kumagai, I. | | Deposit date: | 2002-11-01 | | Release date: | 2003-12-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
To be Published
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2JJV
 | | Structure of human signal regulatory protein (sirp) beta(2) | | Descriptor: | CHLORIDE ION, SIGNAL-REGULATORY PROTEIN BETA 1., SULFATE ION | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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1JFQ
 | | ANTIGEN-BINDING FRAGMENT OF THE MURINE ANTI-PHENYLARSONATE ANTIBODY 36-71, "FAB 36-71" | | Descriptor: | ANTIGEN-BINDING FRAGMENT OF ANTI-PHENYLARSONATE ANTIBODY | | Authors: | Parhami-Seren, B, Viswanathan, M, Strong, R.K, Margolies, M.N. | | Deposit date: | 2001-06-21 | | Release date: | 2002-02-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of mutants of high-affinity and low-affinity
p-azophenylarsonate-specific antibodies generated by alanine
scanning of heavy chain
complementarity-determining region 2.
J.Immunol., 167, 2001
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1JV5
 | | Anti-blood group A Fv | | Descriptor: | Ig chain heavy chain precursor V region, Ig kappa chain precursor V region | | Authors: | Thomas, R, Patenaude, S.I, MacKenzie, C.R, To, R, Hirama, T, Young, N.M, Evans, S.V. | | Deposit date: | 2001-08-28 | | Release date: | 2002-01-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of an anti-blood group A Fv and improvement of its binding affinity without loss of specificity.
J.Biol.Chem., 277, 2002
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1I85
 | | CRYSTAL STRUCTURE OF THE CTLA-4/B7-2 COMPLEX | | Descriptor: | CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, T LYMPHOCYTE ACTIVATION ANTIGEN CD86 | | Authors: | Schwartz, J.-C.D, Zhang, X, Fedorov, A.A, Nathenson, S.G, Almo, S.C. | | Deposit date: | 2001-03-12 | | Release date: | 2001-04-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis for co-stimulation by the human CTLA-4/B7-2 complex.
Nature, 410, 2001
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1I8K
 | | CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | | Authors: | Landry, R.C, Klimowicz, A.C, Lavictoire, S.J, Borisova, S, Kottachchi, D.T, Lorimer, I.A, Evans, S.V. | | Deposit date: | 2001-03-14 | | Release date: | 2002-03-14 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.
J.Mol.Biol., 308, 2001
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2IF7
 | | Crystal Structure of NTB-A | | Descriptor: | CALCIUM ION, CHLORIDE ION, SLAM family member 6 | | Authors: | Cao, E, Ramagopal, U.A, Fedorov, A.A, Fedorov, E.V, Nathenson, S.G, Almo, S.C. | | Deposit date: | 2006-09-20 | | Release date: | 2006-10-17 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | NTB-A Receptor Crystal Structure: Insights into Homophilic Interactions in the Signaling Lymphocytic Activation Molecule Receptor Family.
Immunity, 25, 2006
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1I9E
 | | TCR DOMAIN | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYTOTOXIC TCELL VALPHA DOMAIN | | Authors: | Rudolph, M.G, Huang, M, Teyton, L, Wilson, I.A. | | Deposit date: | 2001-03-19 | | Release date: | 2001-12-05 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of an isolated V(alpha) domain of the 2C T-cell receptor.
J.Mol.Biol., 314, 2001
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1I8I
 | | CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT ROOM TEMPERATURE | | Descriptor: | EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | | Authors: | Landry, R.C, Klimowicz, A.C, Lavictoire, S.J, Borisova, S, Kottachchi, D.T, Lorimer, I.A, Evans, S.V. | | Deposit date: | 2001-03-14 | | Release date: | 2002-03-14 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.
J.Mol.Biol., 308, 2001
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2JJU
 | | Structure of human signal regulatory protein (sirp) beta | | Descriptor: | CHLORIDE ION, SIGNAL REGULATORY PROTEIN BETA-1, SULFATE ION | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2I27
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2JJW
 | | Structure of human signal regulatory protein (sirp) gamma | | Descriptor: | SIGNAL REGULATORY PROTEIN GAMMA | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2G5R
 | | Crystal structure of Siglec-7 in complex with methyl-9-(aminooxalyl-amino)-9-deoxyNeu5Ac (oxamido-Neu5Ac) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, Sialic acid-binding Ig-like lectin 7, ... | | Authors: | Attrill, H, Crocker, P.R, van Aalten, D.M. | | Deposit date: | 2006-02-23 | | Release date: | 2006-06-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design.
Biochem.J., 397, 2006
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1HKF
 | | The three dimensional structure of NK cell receptor Nkp44, a triggering partner in natural cytotoxicity | | Descriptor: | NK CELL ACTIVATING RECEPTOR | | Authors: | Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D. | | Deposit date: | 2003-03-10 | | Release date: | 2003-06-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Three-Dimensional Structure of the Human Nk Cell Receptor Nkp44, a Triggering Partner in Natural Cytotoxicity
Structure, 11, 2003
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2HP4
 | | Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor | | Descriptor: | GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain | | Authors: | Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F. | | Deposit date: | 2006-07-17 | | Release date: | 2007-02-06 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
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2HRL
 | | Siglec-7 in complex with GT1b | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid-(2-3)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... | | Authors: | Attrill, H, Imamura, A, Sharma, R.S, Kiso, M, Crocker, P.R, van Aalten, D.M.F. | | Deposit date: | 2006-07-20 | | Release date: | 2006-08-15 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Siglec-7 Undergoes a Major Conformational Change When Complexed with the {alpha}(2,8)-Disialylganglioside GT1b
J.Biol.Chem., 281, 2006
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2GKI
 | | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity | | Descriptor: | nuclease | | Authors: | Kim, Y.R, Kim, J.S, Lee, S.H, Lee, W.R, Sohn, J.N, Chung, Y.C, Shim, H.K, Lee, S.C, Kwon, M.H, Kim, Y.S. | | Deposit date: | 2006-04-02 | | Release date: | 2006-04-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity.
J.Biol.Chem., 281, 2006
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2I24
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2GK2
 | | Crystal structure of the N terminal domain of human CEACAM1 | | Descriptor: | Carcinoembryonic antigen-related cell adhesion molecule 1, GLYCEROL, NICKEL (II) ION | | Authors: | Fedarovich, A, Tomberg, J, Nicholas, R.A, Davies, C. | | Deposit date: | 2006-03-31 | | Release date: | 2006-09-05 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of the N-terminal domain of human CEACAM1: binding target of the opacity proteins during invasion of Neisseria meningitidis and N. gonorrhoeae.
Acta Crystallogr.,Sect.D, 62, 2006
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6L7Z
 | | Solution NMR structure of the N-terminal immunoglobulin variable domain of BTNL2 | | Descriptor: | Butyrophilin-like protein 2 | | Authors: | Basak, A.J, Lee, W, Samanta, D, De, S. | | Deposit date: | 2019-11-03 | | Release date: | 2020-10-14 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural Insights into N-terminal IgV Domain of BTNL2, a T Cell Inhibitory Molecule, Suggests a Non-canonical Binding Interface for Its Putative Receptors.
J.Mol.Biol., 432, 2020
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