8FOH
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![BU of 8foh by Molmil](/molmil-images/mine/8foh) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | Deposit date: | 2022-12-30 | Release date: | 2023-05-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOC
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![BU of 8foc by Molmil](/molmil-images/mine/8foc) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | Deposit date: | 2022-12-30 | Release date: | 2023-05-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOD
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![BU of 8fod by Molmil](/molmil-images/mine/8fod) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | Deposit date: | 2022-12-30 | Release date: | 2023-05-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOE
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![BU of 8foe by Molmil](/molmil-images/mine/8foe) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | Deposit date: | 2022-12-30 | Release date: | 2023-05-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.6 Å) | Cite: | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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8FOK
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![BU of 8fok by Molmil](/molmil-images/mine/8fok) | Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state | Descriptor: | DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. | Deposit date: | 2022-12-30 | Release date: | 2023-05-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
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6WQ6
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![BU of 6wq6 by Molmil](/molmil-images/mine/6wq6) | |
6WQS
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![BU of 6wqs by Molmil](/molmil-images/mine/6wqs) | Xanthomonas citri Methionyl-tRNA synthetase in complex with REP8839 | Descriptor: | 2-{[3-({[4-bromo-5-(1-fluoroethenyl)-3-methylthiophen-2-yl]methyl}amino)propyl]amino}quinolin-4(1H)-one, Methionine--tRNA ligase, ZINC ION | Authors: | Mercaldi, G.F, Benedetti, C.E. | Deposit date: | 2020-04-29 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium. J.Biol.Chem., 296, 2021
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6WQT
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![BU of 6wqt by Molmil](/molmil-images/mine/6wqt) | Xanthomonas citri Methionyl-tRNA synthetase in complex with REP3123 | Descriptor: | 5-[(3-{[(4R)-6,8-dibromo-3,4-dihydro-2H-1-benzopyran-4-yl]amino}propyl)amino]thieno[3,2-b]pyridin-7(6H)-one, Methionine--tRNA ligase, ZINC ION | Authors: | Mercaldi, G.F, Benedetti, C.E. | Deposit date: | 2020-04-29 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium. J.Biol.Chem., 296, 2021
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6WQI
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![BU of 6wqi by Molmil](/molmil-images/mine/6wqi) | Xanthomonas citri Methionyl-tRNA synthetase (apo) | Descriptor: | Methionine--tRNA ligase, ZINC ION | Authors: | Mercaldi, G.F, Benedetti, C.E. | Deposit date: | 2020-04-28 | Release date: | 2021-04-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium. J.Biol.Chem., 296, 2021
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7TV5
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![BU of 7tv5 by Molmil](/molmil-images/mine/7tv5) | Disulfide-rich venom peptide lasiocepsin: P20A mutant | Descriptor: | Lasiocepsin | Authors: | Cabalteja, C.C, Harmon, T.H, Rao, S.R, Horne, W.S. | Deposit date: | 2022-02-04 | Release date: | 2022-05-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Heterogeneous-Backbone Proteomimetic Analogues of Lasiocepsin, a Disulfide-Rich Antimicrobial Peptide with a Compact Tertiary Fold. Acs Chem.Biol., 17, 2022
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7TV8
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![BU of 7tv8 by Molmil](/molmil-images/mine/7tv8) | Heterogeneous-backbone proteomimetic analogue of the disulfide-rich venom peptide lasiocepsin: D-Ala modified loop | Descriptor: | Lasiocepsin heterogeneous-backbone proteomimetic analogue | Authors: | Cabalteja, C.C, Harmon, T.H, Rao, S.R, Horne, W.S. | Deposit date: | 2022-02-04 | Release date: | 2022-05-04 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Heterogeneous-Backbone Proteomimetic Analogues of Lasiocepsin, a Disulfide-Rich Antimicrobial Peptide with a Compact Tertiary Fold. Acs Chem.Biol., 17, 2022
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7TV7
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![BU of 7tv7 by Molmil](/molmil-images/mine/7tv7) | Heterogeneous-backbone proteomimetic analogue of the disulfide-rich venom peptide lasiocepsin: beta-3-Lys modified loop | Descriptor: | Lasiocepsin heterogeneous-backbone proteomimetic analogue | Authors: | Cabalteja, C.C, Harmon, T.H, Rao, S.R, Horne, W.S. | Deposit date: | 2022-02-04 | Release date: | 2022-05-04 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Heterogeneous-Backbone Proteomimetic Analogues of Lasiocepsin, a Disulfide-Rich Antimicrobial Peptide with a Compact Tertiary Fold. Acs Chem.Biol., 17, 2022
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5L3A
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![BU of 5l3a by Molmil](/molmil-images/mine/5l3a) | Fragment-based discovery of 6-arylindazole JAK inhibitors | Descriptor: | Tyrosine-protein kinase JAK2, ~{N}-(1~{H}-indazol-4-yl)methanesulfonamide | Authors: | Soerensen, M.D, Dack, K.N, Greve, D.R, Ritzen, A. | Deposit date: | 2016-04-06 | Release date: | 2016-04-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Fragment-Based Discovery of 6-Arylindazole JAK Inhibitors. Acs Med.Chem.Lett., 7, 2016
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3QSL
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![BU of 3qsl by Molmil](/molmil-images/mine/3qsl) | Structure of CAE31940 from Bordetella bronchiseptica RB50 | Descriptor: | CITRIC ACID, Putative exported protein | Authors: | Bajor, J, Kagan, O, Chruszcz, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-21 | Release date: | 2011-03-23 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of pyrimidine/thiamin biosynthesis precursor-like domain-containing protein CAE31940 from proteobacterium Bordetella bronchiseptica RB50, and evolutionary insight into the NMT1/THI5 family. J Struct Funct Genomics, 15, 2014
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2VL0
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4C92
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![BU of 4c92 by Molmil](/molmil-images/mine/4c92) | Crystal structure of the yeast Lsm1-7 complex | Descriptor: | SM-LIKE PROTEIN LSM1, U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2, U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3, ... | Authors: | Sharif, H, Conti, E. | Deposit date: | 2013-10-02 | Release date: | 2013-10-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.299 Å) | Cite: | Architecture of the Lsm1-7-Pat1 Complex: A Conserved Assembly in Eukaryotic Mrna Turnover Cell Rep., 5, 2013
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4BXF
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4NTO
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![BU of 4nto by Molmil](/molmil-images/mine/4nto) | Crystal structure of D60A mutant of Arabidopsis ACD11 (accelerated-cell-death 11) complexed with C2 ceramide-1-phosphate (d18:1/2:0) at 2.15 Angstrom resolution | Descriptor: | (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, DI(HYDROXYETHYL)ETHER, accelerated-cell-death 11 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-12-02 | Release date: | 2014-02-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
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4NT1
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![BU of 4nt1 by Molmil](/molmil-images/mine/4nt1) | Crystal structure of apo-form of Arabidopsis ACD11 (accelerated-cell-death 11) at 1.8 Angstrom resolution | Descriptor: | SODIUM ION, accelerated-cell-death 11 | Authors: | Simanshu, D.K, Brown, R.E, Patel, D.J. | Deposit date: | 2013-11-29 | Release date: | 2014-02-05 | Last modified: | 2014-02-19 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Arabidopsis Accelerated Cell Death 11, ACD11, Is a Ceramide-1-Phosphate Transfer Protein and Intermediary Regulator of Phytoceramide Levels. Cell Rep, 6, 2014
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3ZXG
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![BU of 3zxg by Molmil](/molmil-images/mine/3zxg) | lysenin sphingomyelin complex | Descriptor: | LYSENIN, SULFATE ION, TRIMETHYL-[2-[[(2S,3S)-2-(OCTADECANOYLAMINO)-3-OXIDANYL-BUTOXY]-OXIDANYL-PHOSPHORYL]OXYETHYL]AZANIUM | Authors: | De Colibus, L, Sonnen, A.F.P, Morris, K.J, Siebert, C.A, Abrusci, P, Plitzko, J, Hodnik, V, Leippe, M, Volpi, E, Anderluh, G, Gilbert, R.J.C. | Deposit date: | 2011-08-10 | Release date: | 2012-09-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structures of Lysenin Reveal a Shared Evolutionary Origin for Pore-Forming Proteins and its Mode of Sphingomyelin Recognition. Structure, 20, 2012
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3SEB
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![BU of 3seb by Molmil](/molmil-images/mine/3seb) | STAPHYLOCOCCAL ENTEROTOXIN B | Descriptor: | STAPHYLOCOCCAL ENTEROTOXIN B | Authors: | Papageorgiou, A.C, Acharya, K.R. | Deposit date: | 1997-11-26 | Release date: | 1998-05-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal structure of microbial superantigen staphylococcal enterotoxin B at 1.5 A resolution: implications for superantigen recognition by MHC class II molecules and T-cell receptors. J.Mol.Biol., 277, 1998
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2J3Z
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![BU of 2j3z by Molmil](/molmil-images/mine/2j3z) | Crystal structure of the enzymatic component C2-I of the C2-toxin from Clostridium botulinum at pH 6.1 | Descriptor: | C2 TOXIN COMPONENT I, COBALT (II) ION, GLYCEROL, ... | Authors: | Schleberger, C, Hochmann, H, Barth, H, Aktories, K, Schulz, G.E. | Deposit date: | 2006-08-23 | Release date: | 2006-10-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Action of the Binary C2 Toxin from Clostridium Botulinum. J.Mol.Biol., 364, 2006
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6O4M
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![BU of 6o4m by Molmil](/molmil-images/mine/6o4m) | Racemic melittin | Descriptor: | D-Melittin, Melittin, SULFATE ION | Authors: | Kurgan, K.W, Bingman, C.A, Gellman, S.H, Forest, K.T. | Deposit date: | 2019-02-28 | Release date: | 2019-05-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Retention of Native Quaternary Structure in Racemic Melittin Crystals. J.Am.Chem.Soc., 141, 2019
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8DTO
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![BU of 8dto by Molmil](/molmil-images/mine/8dto) | Vaccine elicited Antibody MU89 bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Stalls, V, Acharya, P. | Deposit date: | 2022-07-26 | Release date: | 2023-04-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction. Cell Host Microbe, 32, 2024
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8DY6
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![BU of 8dy6 by Molmil](/molmil-images/mine/8dy6) | Vaccine elicited Antibody MU89+S27Y bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Stalls, V, Acharya, P. | Deposit date: | 2022-08-03 | Release date: | 2023-04-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.32 Å) | Cite: | Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction. Cell Host Microbe, 32, 2024
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