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3KS8
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BU of 3ks8 by Molmil
Crystal structure of Reston ebolavirus VP35 RNA binding domain in complex with 18bp dsRNA
Descriptor: 5'-R(*AP*GP*AP*AP*GP*GP*AP*GP*GP*GP*AP*GP*GP*GP*AP*GP*GP*A)-3', 5'-R(*UP*CP*CP*UP*CP*CP*CP*UP*CP*CP*CP*UP*CP*CP*UP*UP*CP*U)-3', Polymerase cofactor VP35
Authors:Kimberlin, C.R, Bornholdt, Z.A, Li, S, Woods, V.L, Macrae, I.J, Saphire, E.O.
Deposit date:2009-11-20
Release date:2010-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression.
Proc.Natl.Acad.Sci.USA, 107, 2009
2ASJ
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BU of 2asj by Molmil
oxoG-modified Preinsertion Binary Complex
Descriptor: 5'-D(*CP*TP*AP*AP*CP*(8OG)*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', CALCIUM ION, ...
Authors:Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J.
Deposit date:2005-08-23
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
4QBT
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BU of 4qbt by Molmil
Crystal structure of tyrosine bound human tyrosyl tRNA synthetase
Descriptor: GLYCEROL, PHOSPHATE ION, POTASSIUM ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-05-08
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
4Q93
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BU of 4q93 by Molmil
Crystal structure of resveratrol bound human tyrosyl tRNA synthetase
Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ...
Authors:Mathew, S, Schimmel, P.
Deposit date:2014-04-28
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Nature, 519, 2014
2L9J
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BU of 2l9j by Molmil
hRSV M2-1 core domain structure
Descriptor: Matrix protein 2-1
Authors:Dubosclard, V, Blondot, M, Bontems, F, Eleouet, J, Sizun, C.
Deposit date:2011-02-12
Release date:2012-02-15
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein.
Plos Pathog., 8, 2012
5J0R
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BU of 5j0r by Molmil
Binary complex crystal structure of DNA polymerase Beta with C:A mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0X
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BU of 5j0x by Molmil
Binary complex crystal structure of DNA polymerase Beta with T:G mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0O
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BU of 5j0o by Molmil
Binary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus
Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0W
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BU of 5j0w by Molmil
Binary complex crystal structure of DNA polymerase Beta with T:C mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
8GAP
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BU of 8gap by Molmil
Structure of LARP7 protein p65-telomerase RNA complex in telomerase
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J.
Deposit date:2023-02-23
Release date:2023-06-28
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
5J0Y
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BU of 5j0y by Molmil
Binary complex crystal structure of DNA polymerase Beta with T:T mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0P
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BU of 5j0p by Molmil
Binary complex crystal structure of DNA polymerase Beta with A:C mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0S
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BU of 5j0s by Molmil
Binary complex crystal structure of DNA polymerase Beta with C:T mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0U
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BU of 5j0u by Molmil
Binary complex crystal structure of DNA polymerase Beta with G:G mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
4XQ8
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BU of 4xq8 by Molmil
Human DNA polymerase lambda- MgdATP binary complex and complex with 6 paired DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Tsai, M.D, Liu, M.S.
Deposit date:2015-01-19
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5J0Q
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BU of 5j0q by Molmil
Binary complex crystal structure of DNA polymerase Beta with A:G mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
5J0T
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BU of 5j0t by Molmil
Binary complex crystal structure of DNA polymerase Beta with G:A mismatch at the primer terminus
Descriptor: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ...
Authors:Batra, V.K, Wilson, S.H.
Deposit date:2016-03-28
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism.
Structure, 24, 2016
2PFQ
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BU of 2pfq by Molmil
Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ...
Authors:Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
Deposit date:2007-04-05
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the catalytic metal during polymerization by DNA polymerase lambda.
DNA Repair, 6, 2007
4H61
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BU of 4h61 by Molmil
Structure of the Schizosaccharomyces pombe Mediator subunit Med6
Descriptor: Mediator of RNA polymerase II transcription subunit 6
Authors:Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P.
Deposit date:2012-09-19
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the Mediator head module.
Nature, 492, 2012
2PFO
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BU of 2pfo by Molmil
DNA Polymerase lambda in complex with DNA and dUPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, ...
Authors:Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
Deposit date:2007-04-05
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of the catalytic metal during polymerization by DNA polymerase lambda.
DNA Repair, 6, 2007
1FW5
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BU of 1fw5 by Molmil
SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1
Descriptor: NONSTRUCTURAL PROTEIN NSP1
Authors:Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L.
Deposit date:2000-09-21
Release date:2001-09-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Membrane binding mechanism of an RNA virus-capping enzyme.
J.Biol.Chem., 275, 2001
2PFN
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BU of 2pfn by Molmil
Na in the active site of DNA Polymerase lambda
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ...
Authors:Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
Deposit date:2007-04-05
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Role of the catalytic metal during polymerization by DNA polymerase lambda.
DNA Repair, 6, 2007
3IYB
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BU of 3iyb by Molmil
Poliovirus early RNA-release intermediate
Descriptor: Genome polyprotein, Precursor polyprotein, VP1 core
Authors:Levy, H.C, Bostina, M, Filman, D.J, Hogle, J.M.
Deposit date:2009-07-21
Release date:2010-03-16
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
J.Virol., 84, 2010
2PFP
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BU of 2pfp by Molmil
DNA Polymerase lambda in complex with DNA and dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ...
Authors:Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
Deposit date:2007-04-05
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Role of the catalytic metal during polymerization by DNA polymerase lambda.
DNA Repair, 6, 2007
3FBI
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BU of 3fbi by Molmil
Structure of the Mediator submodule Med7N/31
Descriptor: Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7
Authors:Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P.
Deposit date:2008-11-19
Release date:2008-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009

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數據於2024-07-24公開中

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