6A5U
| RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation | Descriptor: | DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... | Authors: | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | Deposit date: | 2018-06-25 | Release date: | 2018-10-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5P
| RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome | Descriptor: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | Deposit date: | 2018-06-25 | Release date: | 2018-10-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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6A5O
| RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome | Descriptor: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. | Deposit date: | 2018-06-25 | Release date: | 2018-10-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (9.9 Å) | Cite: | Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
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7NW0
| RNA polymerase II pre-initiation complex with open promoter DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CDK-activating kinase assembly factor MAT1, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVZ
| RNA polymerase II pre-initiation complex with closed promoter DNA in distal position | Descriptor: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (7.2 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7NVY
| RNA polymerase II pre-initiation complex with closed promoter DNA in proximal position | Descriptor: | CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Aibara, S, Schilbach, S, Cramer, P. | Deposit date: | 2021-03-16 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (7.3 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7OB9
| Cryo-EM structure of human RNA Polymerase I in elongation state | Descriptor: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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6YSR
| Structure of the P+9 stalled ribosome complex | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | Deposit date: | 2020-04-23 | Release date: | 2020-08-19 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
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6AGB
| Cryo-EM structure of yeast Ribonuclease P | Descriptor: | RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ... | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | Deposit date: | 2018-08-10 | Release date: | 2018-10-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P. Science, 362, 2018
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8H1B
| Crystal structure of MnmM from S. aureus complexed with SAM and tRNA anti-codon stem loop (ASL) (1.55 A) | Descriptor: | RNA (5'-R(*AP*CP*GP*GP*AP*CP*UP*UP*UP*GP*AP*CP*UP*CP*CP*GP*U)-3'), S-ADENOSYLMETHIONINE, SODIUM ION, ... | Authors: | Kim, J, Cho, G, Lee, J. | Deposit date: | 2022-10-01 | Release date: | 2023-01-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
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7S7B
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7S7C
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5M0I
| Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ASH1-E3 element, ... | Authors: | Edelmann, F.T, Janowski, R, Niessing, D. | Deposit date: | 2016-10-05 | Release date: | 2017-01-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex. Nat. Struct. Mol. Biol., 24, 2017
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7KEF
| RNA polymerase II elongation complex with unnatural base dTPT3, rNaM in swing state | Descriptor: | (1S)-1,4-anhydro-1-(3-methoxynaphthalen-2-yl)-5-O-phosphono-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2020-10-10 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.89 Å) | Cite: | Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
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7KEE
| RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site | Descriptor: | (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | Authors: | Oh, J, Wang, D. | Deposit date: | 2020-10-10 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
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8CTI
| Cryo-EM structure of human METTL1-WDR4-tRNA(Val) complex | Descriptor: | tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA-Val-TAC-2-1 | Authors: | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fischer, E.S, Gregory, R.I. | Deposit date: | 2022-05-14 | Release date: | 2022-12-07 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4. Nature, 613, 2023
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7KED
| RNA polymerase II elongation complex with unnatural base dTPT3 | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | Authors: | Oh, J, Wang, W, Wang, D. | Deposit date: | 2020-10-10 | Release date: | 2021-06-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II. Nat.Chem.Biol., 17, 2021
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6N4O
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5G5L
| RNA polymerase I-Rrn3 complex at 4.8 A resolution | Descriptor: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | Authors: | Engel, C, Plitzko, J, Cramer, P. | Deposit date: | 2016-05-26 | Release date: | 2016-07-27 | Last modified: | 2018-10-24 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
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7KI3
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6HLQ
| Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | Deposit date: | 2018-09-11 | Release date: | 2019-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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5XON
| RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | Descriptor: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | Authors: | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | Deposit date: | 2017-05-29 | Release date: | 2017-08-16 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.83 Å) | Cite: | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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6HLR
| Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | Deposit date: | 2018-09-11 | Release date: | 2019-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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6HKO
| Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | Deposit date: | 2018-09-07 | Release date: | 2019-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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7ZWD
| Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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