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1LC6
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BU of 1lc6 by Molmil
Solution Structure of the U6 Intramolecular Stem-loop RNA
Descriptor: U6 Intramolecular Stem-loop RNA
Authors:Huppler, A, Nikstad, L.J, Allmann, A.M, Brow, D.A, Butcher, S.E.
Deposit date:2002-04-05
Release date:2002-05-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure.
Nat.Struct.Biol., 9, 2002
3HYF
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BU of 3hyf by Molmil
Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor
Descriptor: 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ...
Authors:Lansdon, E.B, Kirschberg, T.A.
Deposit date:2009-06-22
Release date:2009-10-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
J.Med.Chem., 52, 2009
247D
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BU of 247d by Molmil
CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE
Descriptor: DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3')
Authors:Portmann, S, Grimm, S, Workman, C, Usman, N, Egli, M.
Deposit date:1996-02-02
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
248D
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BU of 248d by Molmil
CRYSTAL STRUCTURES OF AN A-FORM DUPLEX WITH SINGLE-ADENOSINE BULGES AND A CONFORMATIONAL BASIS FOR SITE SPECIFIC RNA SELF-CLEAVAGE
Descriptor: DNA/RNA (5'-R(*GP*CP*GP*)-D(*AP*TP*AP*TP*AP*)-R(*CP*GP*C)-3'), ORTHORHOMBIC, SPERMINE
Authors:Portmann, S, Grimm, S, Workman, C, Usman, N, Egli, M.
Deposit date:1996-02-02
Release date:1996-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage.
Chem.Biol., 3, 1996
2MKI
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BU of 2mki by Molmil
Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 4 (CPEB4) in complex with RNA
Descriptor: Cytoplasmic polyadenylation element-binding protein 4, RNA (5'-R(*CP*UP*UP*UP*A)-3')
Authors:Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T.
Deposit date:2014-02-07
Release date:2014-07-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins
Genes Dev., 28, 2014
2RQJ
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BU of 2rqj by Molmil
Quadruplex structure of an RNA aptamer against bovine prion protein
Descriptor: RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3')
Authors:Katahira, M, Mashima, T, Matsugami, A, Nishikawa, F, Nishikawa, S.
Deposit date:2009-07-18
Release date:2009-11-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Unique quadruplex structure and interaction of an RNA aptamer against bovine prion protein
Nucleic Acids Res., 37, 2009
2MKK
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BU of 2mkk by Molmil
Structural model of tandem RRM domains of cytoplasmic polyadenylation element binding protein 1 (CPEB1) in complex with RNA
Descriptor: Cytoplasmic polyadenylation element-binding protein 1, RNA (5'-R(*UP*UP*UP*UP*A)-3')
Authors:Afroz, T, Skrisovska, L, Belloc, E, Boixet, J.G, Mendez, R, Allain, F.H.-T.
Deposit date:2014-02-07
Release date:2014-07-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins
Genes Dev., 28, 2014
1TRA
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BU of 1tra by Molmil
RESTRAINED REFINEMENT OF THE MONOCLINIC FORM OF YEAST PHENYLALANINE TRANSFER RNA. TEMPERATURE FACTORS AND DYNAMICS, COORDINATED WATERS, AND BASE-PAIR PROPELLER TWIST ANGLES
Descriptor: MAGNESIUM ION, TRNAPHE
Authors:Westhof, E, Sundaralingam, M.
Deposit date:1986-05-16
Release date:1986-07-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Restrained refinement of the monoclinic form of yeast phenylalanine transfer RNA. Temperature factors and dynamics, coordinated waters, and base-pair propeller twist angles.
Biochemistry, 25, 1986
6H9X
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BU of 6h9x by Molmil
Klebsiella pneumoniae Seryl-tRNA Synthetase in Complex with the Intermediate Analog 5'-O-(N-(L-Seryl)-Sulfamoyl)Adenosine
Descriptor: 1,2-ETHANEDIOL, 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CALCIUM ION, ...
Authors:Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D.
Deposit date:2018-08-06
Release date:2019-05-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.
Eur.J.Med.Chem., 174, 2019
1ZIF
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BU of 1zif by Molmil
GAAA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*AP*AP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
1ZIG
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BU of 1zig by Molmil
GAGA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*AP*GP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
1ZIH
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BU of 1zih by Molmil
GCAA RNA TETRALOOP, NMR, 10 STRUCTURES
Descriptor: RNA (5'-R(*GP*GP*GP*CP*GP*CP*AP*AP*GP*CP*CP*U)-3')
Authors:Jucker, F.M, Heus, H.A, Yip, P.F, Moors, E, Pardi, A.
Deposit date:1996-07-27
Release date:1997-03-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A network of heterogeneous hydrogen bonds in GNRA tetraloops.
J.Mol.Biol., 264, 1996
4C7O
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BU of 4c7o by Molmil
The structural basis of FtsY recruitment and GTPase activation by SRP RNA
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE PROTEIN, ...
Authors:Voigts-Hoffmann, F, Schmitz, N, Shen, K, Shan, S.O, Ataide, S.F, Ban, N.
Deposit date:2013-09-23
Release date:2013-11-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis of Ftsy Recruitment and Gtpase Activation by Srp RNA
Mol.Cell, 52, 2013
2QTX
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BU of 2qtx by Molmil
Crystal structure of an Hfq-like protein from Methanococcus jannaschii
Descriptor: Uncharacterized protein MJ1435
Authors:Nielsen, J.S, Boggild, A, Andersen, C.B.F, Nielsen, G, Boysen, A, Brodersen, D.E, Valentin-Hansen, P.
Deposit date:2007-08-03
Release date:2007-11-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii.
Rna, 13, 2007
1YMO
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BU of 1ymo by Molmil
Solution structure of the P2b-P3 pseudoknot from human telomerase RNA
Descriptor: Telomerase RNA P2b-P3 pseudoknot
Authors:Theimer, C.A, Blois, C.A, Feigon, J.
Deposit date:2005-01-21
Release date:2005-03-15
Last modified:2023-11-29
Method:SOLUTION NMR
Cite:Structure of the human telomerase RNA pseudoknot reveals conserved tertiary interactions essential for function
Mol.Cell, 17, 2005
6MN8
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BU of 6mn8 by Molmil
Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide
Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, ADENOSINE MONOPHOSPHATE, GLYCINE, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-10-01
Release date:2018-10-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of Prolyl-tRNA Synthetase from Onchocerca volvulus with bound Halofuginone and nucleotide
To Be Published
8AXP
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BU of 8axp by Molmil
Neisseria gonorrhoeae peptidyl-tRNA hydrolase complexed with an XChem hit.
Descriptor: N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]acetamide, Peptidyl-tRNA hydrolase, SULFATE ION
Authors:Roe, S.M, Fearon, D.
Deposit date:2022-08-31
Release date:2022-11-09
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction.
Org.Lett., 24, 2022
1XJR
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BU of 1xjr by Molmil
The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
Descriptor: MAGNESIUM ION, s2m RNA
Authors:Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
Deposit date:2004-09-24
Release date:2005-02-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
6ZK7
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BU of 6zk7 by Molmil
Crystal Structure of human PYROXD1/FAD complex
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1
Authors:Meinhart, A, Asanovic, I, Martinez, J, Clausen, T.
Deposit date:2020-06-30
Release date:2021-05-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol.Cell, 81, 2021
4V35
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BU of 4v35 by Molmil
The Structure of A-PGS from Pseudomonas aeruginosa
Descriptor: ACETATE ION, ALANYL-TRNA-DEPENDENT L-ALANYL- PHOPHATIDYLGLYCEROL SYNTHASE, CALCIUM ION, ...
Authors:Krausze, J, Hebecker, S, Hasenkampf, T, Heinz, D.W, Moser, J.
Deposit date:2014-10-16
Release date:2015-08-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine.
Proc.Natl.Acad.Sci.USA, 112, 2015
8BU8
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BU of 8bu8 by Molmil
Double-motif Single-stranded Paranemic Crossover RNA Triangle (2PXT)
Descriptor: RNA (354-MER)
Authors:Sampedro, N, Andersen, E.S, McRae, E.K.S.
Deposit date:2022-11-30
Release date:2024-01-24
Method:ELECTRON MICROSCOPY (6.56 Å)
Cite:An RNA Paranemic Crossover Triangle as A 3D Module for Cotranscriptional Nanoassembly.
Small, 19, 2023
7ZOG
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BU of 7zog by Molmil
Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in complex with inhibitor
Descriptor: 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, LYSINE, ...
Authors:Dawson, A, Wyllie, S.
Deposit date:2022-04-25
Release date:2022-09-07
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Acs Infect Dis., 8, 2022
4YCW
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BU of 4ycw by Molmil
Crystal structure of cladosporin in complex with plasmodium like human lysyl-tRNA synthetase mutant
Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, LYSINE, Lysine--tRNA ligase, ...
Authors:Fang, P, Wang, J, Guo, M.
Deposit date:2015-02-20
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Specific Inhibition of tRNA Synthetase by ATP Competitive Inhibitor
Chem.Biol., 22, 2015
8BTZ
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BU of 8btz by Molmil
Single-stranded Paranemic Crossover RNA Triangle (PXT)
Descriptor: RNA Paranemic croosover triangle (PXT)
Authors:Sampedro, N, McRae, E.K.S, Andersen, E.S.
Deposit date:2022-11-30
Release date:2022-12-28
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (5.39 Å)
Cite:An RNA Paranemic Crossover Triangle as A 3D Module for Cotranscriptional Nanoassembly.
Small, 19, 2023
7WFX
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BU of 7wfx by Molmil
EVAA-KlAte1
Descriptor: Arginyltransferase, ZINC ION
Authors:Kim, M.K, Kim, B.H, Oh, S.-J, Song, H.K.
Deposit date:2021-12-27
Release date:2022-09-14
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the Ate1 arginyl-tRNA-protein transferase and arginylation of N-degron substrates.
Proc.Natl.Acad.Sci.USA, 119, 2022

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數據於2024-07-10公開中

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