2Q1R

Crystal Structure Analysis of the RNA Dodecamer CGCGAAUUAGCG, with a G-A mismatch.

Summary for 2Q1R

• Entry DOI: 10.2210/pdb2q1r/pdb
• Descriptor: RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3'), MAGNESIUM ION (3 entities in total)
• Functional Keywords: g-a mismatch, rna, rnai
• Total number of polymer chains: 1
• Total formula weight: 3899.97

Authors

Li, F.,Pallan, P.S. (deposition date: 2007-05-25, release date: 2007-10-30, Last modification date: 2024-04-03)

• Primary citation: Li, F.,Pallan, P.S.,Maier, M.A.,Rajeev, K.G.,Mathieu, S.L.,Kreutz, C.,Fan, Y.,Sanghvi, J.,Micura, R.,Rozners, E.,Manoharan, M.,Egli, M.; Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.; Nucleic Acids Res., 35:6424-6438, 2007; PubMed: 17881374; DOI: 10.1093/nar/gkm664

Experimental method

X-RAY DIFFRACTION (1.12 Å)