2YV3
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![BU of 2yv3 by Molmil](/molmil-images/mine/2yv3) | Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Thermus thermophilus HB8 | Descriptor: | Aspartate-semialdehyde dehydrogenase | Authors: | Kagawa, W, Fujikawa, N, Kurumizaka, H, Bessho, Y, Ellis, M.J, Antonyuk, S.V, Strange, R.W, Hasnain, S.S, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-07 | Release date: | 2007-10-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of Aspartate Semialdehyde Dehydrogenase from Thermus thermophilus HB8 To be Published
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4GKV
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![BU of 4gkv by Molmil](/molmil-images/mine/4gkv) | Structure of Escherichia coli AdhP (ethanol-inducible dehydrogenase) with bound NAD | Descriptor: | Alcohol dehydrogenase, propanol-preferring, GLYCEROL, ... | Authors: | Sims, P.A, Thomas, L.M, Harper, A.R, Miner, W.A, Ajufo, H.O, Branscrum, K.M, Kao, L. | Deposit date: | 2012-08-13 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.008 Å) | Cite: | Structure of Escherichia coli AdhP (ethanol-inducible dehydrogenase) with bound NAD. Acta Crystallogr.,Sect.F, 69, 2013
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2YN4
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![BU of 2yn4 by Molmil](/molmil-images/mine/2yn4) | L-2-chlorobutryic acid bound complex L-haloacid dehalogenase from a Rhodobacteraceae family bacterium | Descriptor: | (2S)-2-chlorobutanoic acid, L-HALOACID DEHALOGENASE | Authors: | Novak, H.R, Sayer, C, Isupov, M.N, Paszkiewicz, K, Gotz, D, Spragg, A.M, Littlechild, J.A. | Deposit date: | 2012-10-12 | Release date: | 2013-05-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Marine Rhodobacteraceae L-Haloacid Dehalogenase Contains a Novel His/Glu Dyad that Could Activate the Catalytic Water. FEBS J., 280, 2013
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4DUV
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![BU of 4duv by Molmil](/molmil-images/mine/4duv) | E. coli (lacZ) beta-galactosidase (G974A) 2-deoxy-galactosyl-enzyme and bis-Tris complex | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, ... | Authors: | Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E. | Deposit date: | 2012-02-22 | Release date: | 2013-04-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Glucose Acceptor site of lacZ beta-galactosidase for the synthesis of allolactose - the natural inducer of the lac operon To be Published
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2BXV
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![BU of 2bxv by Molmil](/molmil-images/mine/2bxv) | Dual binding mode of a novel series of DHODH inhibitors | Descriptor: | 2-({[3-FLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID, ACETATE ION, DIHYDROOROTATE DEHYDROGENASE, ... | Authors: | Baumgartner, R, Walloschek, M, Karlik, M, Gotschlich, A, Tasler, S, Mies, J, Leban, J. | Deposit date: | 2005-07-27 | Release date: | 2006-08-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Dual binding mode of a novel series of DHODH inhibitors. J. Med. Chem., 49, 2006
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3VSU
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![BU of 3vsu by Molmil](/molmil-images/mine/3vsu) | The complex structure of XylC with xylobiose | Descriptor: | Xylosidase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Huang, C.H, Sun, Y, Ko, T.P, Ma, Y, Chen, C.C, Zheng, Y, Chan, H.C, Pang, X, Wiegel, J, Shao, W, Guo, R.T. | Deposit date: | 2012-05-09 | Release date: | 2013-02-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The substrate/product-binding modes of a novel GH120 beta-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485 Biochem.J., 448, 2012
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1OM0
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![BU of 1om0 by Molmil](/molmil-images/mine/1om0) | crystal structure of xylanase inhibitor protein (XIP-I) from wheat | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Xylanase Inhibitor Protein I | Authors: | Payan, F, Flatman, R, Porciero, S, Williamson, G, Juge, N, Roussel, A. | Deposit date: | 2003-02-24 | Release date: | 2003-06-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of xylanase inhibitor protein I (XIP-I), a proteinaceous xylanase inhibitor from wheat (Triticum aestivum, var. Soisson). Biochem.J., 372, 2003
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4H7M
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2YDG
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![BU of 2ydg by Molmil](/molmil-images/mine/2ydg) | Ascorbate co-crystallized HEWL. | Descriptor: | ASCORBIC ACID, Lysozyme C, SODIUM ION | Authors: | De la Mora, E, Carmichael, I, Garman, E.F. | Deposit date: | 2011-03-19 | Release date: | 2011-07-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Effective Scavenging at Cryotemperatures: Further Increasing the Dose Tolerance of Protein Crystals. J.Synchrotron.Radiat., 18, 2011
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4H9C
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![BU of 4h9c by Molmil](/molmil-images/mine/4h9c) | Radiation damage study of lysozyme - 0.77 MGy | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C | Authors: | Sutton, K.A, Snell, E.H. | Deposit date: | 2012-09-24 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.1998 Å) | Cite: | Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
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4H9I
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![BU of 4h9i by Molmil](/molmil-images/mine/4h9i) | Radiation damage study of lysozyme - 1.05 MGy | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C | Authors: | Sutton, K.A, Snell, E.H. | Deposit date: | 2012-09-24 | Release date: | 2013-05-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.2002 Å) | Cite: | Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
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4H2G
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![BU of 4h2g by Molmil](/molmil-images/mine/4h2g) | Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with adenosine | Descriptor: | 5'-nucleotidase, ADENOSINE, CALCIUM ION, ... | Authors: | Straeter, N, Knapp, K.M, Zebisch, M, Pippel, J. | Deposit date: | 2012-09-12 | Release date: | 2012-11-28 | Last modified: | 2012-12-26 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling. Structure, 20, 2012
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1OO6
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![BU of 1oo6 by Molmil](/molmil-images/mine/1oo6) | Nitroreductase from e-coli in complex with the dinitrobenzamide prodrug SN23862 | Descriptor: | 5-[BIS-2(CHLORO-ETHYL)-AMINO]-2,4-DINTRO-BENZAMIDE, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | Authors: | Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. | Deposit date: | 2003-03-03 | Release date: | 2003-04-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003
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2BER
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![BU of 2ber by Molmil](/molmil-images/mine/2ber) | Y370G Active Site Mutant of the Sialidase from Micromonospora viridifaciens in complex with beta-Neu5Ac (sialic acid). | Descriptor: | BACTERIAL SIALIDASE, N-acetyl-beta-neuraminic acid, SODIUM ION | Authors: | Newstead, S, Watson, J.N, Bennet, A.J, Taylor, G.L. | Deposit date: | 2004-11-30 | Release date: | 2005-04-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and Mechanism of Action of an Inverting Mutant Sialidase. Biochemistry, 44, 2005
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2Y99
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![BU of 2y99 by Molmil](/molmil-images/mine/2y99) | Crystal Structure of cis-Biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)from Pandoraea pnomenusa strain B-356 complex with co-enzyme NAD | Descriptor: | CIS-2,3-DIHYDROBIPHENYL-2,3-DIOL DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Dhindwal, S, Patil, D.N, Kumar, P. | Deposit date: | 2011-02-12 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Biochemical Studies and Ligand-Bound Structures of Biphenyl Dehydrogenase from Pandoraea Pnomenusa Strain B-356 Reveal a Basis for Broad Specificity of the Enzyme. J.Biol.Chem., 286, 2011
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3W1L
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![BU of 3w1l by Molmil](/molmil-images/mine/3w1l) | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate | Descriptor: | 5-chloro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... | Authors: | Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. | Deposit date: | 2012-11-16 | Release date: | 2013-11-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-chloroorotate TO BE PUBLISHED
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3VWO
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3W1X
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![BU of 3w1x by Molmil](/molmil-images/mine/3w1x) | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-121 | Descriptor: | 5-{2-[4-(cyanomethyl)phenyl]ethyl}-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... | Authors: | Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. | Deposit date: | 2012-11-22 | Release date: | 2013-11-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-121. To be Published
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1OFE
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![BU of 1ofe by Molmil](/molmil-images/mine/1ofe) | |
5P9Z
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![BU of 5p9z by Molmil](/molmil-images/mine/5p9z) | humanized rat COMT in complex with 6-(4-fluorophenyl)quinazolin-8-ol | Descriptor: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, 6-(4-fluorophenyl)quinazolin-8-ol, CHLORIDE ION, ... | Authors: | Ehler, A, Lerner, C, Rudolph, M.G. | Deposit date: | 2016-10-19 | Release date: | 2017-11-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of a COMT complex To be published
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2Z19
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![BU of 2z19 by Molmil](/molmil-images/mine/2z19) | |
4H5U
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![BU of 4h5u by Molmil](/molmil-images/mine/4h5u) | Structural insights into yeast Nit2: wild-type yeast Nit2 | Descriptor: | CACODYLATE ION, GLYCEROL, Probable hydrolase NIT2 | Authors: | Liu, H, Qiu, X, Zhang, M, Gao, Y, Niu, L, Teng, M. | Deposit date: | 2012-09-18 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structures of enzyme-intermediate complexes of yeast Nit2: insights into its catalytic mechanism and different substrate specificity compared with mammalian Nit2 Acta Crystallogr.,Sect.D, 69, 2013
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4HGO
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1X39
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![BU of 1x39 by Molmil](/molmil-images/mine/1x39) | Crystal structure of barley beta-D-glucan glucohydrolase isoenzyme exo1 in complex with gluco-phenylimidazole | Descriptor: | (5R,6R,7S,8S)-3-(ANILINOMETHYL)-5,6,7,8-TETRAHYDRO-5-(HYDROXYMETHYL)-IMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[beta-D-xylopyranose-(1-2)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Hrmova, M, Streltsov, V.A, Smith, B.J, Vasella, A, Varghese, J.N, Fincher, G.B. | Deposit date: | 2005-05-02 | Release date: | 2005-12-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural rationale for low-nanomolar binding of transition state mimics to a family GH3 beta-D-glucan glucohydrolase from barley. Biochemistry, 44, 2005
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2ZB4
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![BU of 2zb4 by Molmil](/molmil-images/mine/2zb4) | Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and 15-keto-PGE2 | Descriptor: | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin reductase 2, ... | Authors: | Wu, Y.H, Wang, A.H.J, Ko, T.P, Guo, R.T, Hu, S.M, Chuang, L.M. | Deposit date: | 2007-10-16 | Release date: | 2008-09-30 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16, 2008
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