2ZB4
Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and 15-keto-PGE2
Summary for 2ZB4
Entry DOI | 10.2210/pdb2zb4/pdb |
Related | 2ZB3 2ZB7 2ZB8 |
Descriptor | Prostaglandin reductase 2, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total) |
Functional Keywords | rossmann fold, alternative splicing, cytoplasm, nadp, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm (By similarity): Q8N8N7 |
Total number of polymer chains | 1 |
Total formula weight | 40439.39 |
Authors | Wu, Y.H.,Wang, A.H.J.,Ko, T.P.,Guo, R.T.,Hu, S.M.,Chuang, L.M. (deposition date: 2007-10-16, release date: 2008-09-30, Last modification date: 2023-11-01) |
Primary citation | Wu, Y.H.,Ko, T.P.,Guo, R.T.,Hu, S.M.,Chuang, L.M.,Wang, A.H.J. Structural basis for catalytic and inhibitory mechanisms of human prostaglandin reductase PTGR2. Structure, 16:1714-1723, 2008 Cited by PubMed: 19000823DOI: 10.1016/j.str.2008.09.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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