2ZB4
Crystal structure of human 15-ketoprostaglandin delta-13-reductase in complex with NADP and 15-keto-PGE2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Prostaglandin reductase 2 | polymer | 357 | 38961.3 | 1 | UniProt (Q8N8N7) Pfam (PF16884) Pfam (PF00107) In PDB | Homo sapiens (Human) | PTGR2, 15-oxoprostaglandin 13-reductase, Zinc-binding alcohol dehydrogenase domain-containing protein 1 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | A | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | non-polymer | 350.4 | 1 | Chemie (5OP) | |||
| 5 | water | water | 18.0 | 618 | Chemie (HOH) |
Sequence modifications
A: 1 - 351 (UniProt: Q8N8N7)
| PDB | External Database | Details |
|---|---|---|
| Ala -6 | - | expression tag |
| Ala -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38961.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1478.1 | |
| All* | Total formula weight | 40439.4 |
