PDB: 5373 resultsInfo pagesStatus searchChemie searchBIRD

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6R94	Cryo-EM structure of NCP_THF2(-3) Descriptor: Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... Authors: Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. Deposit date: 2019-04-02 Release date: 2019-06-12 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
8HGF	Human PKM2 mutant - C326S Descriptor: Pyruvate kinase PKM Authors: Chen, Y.-C, Lin, K.-T, Cheng, H.-C. Deposit date: 2022-11-14 Release date: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Human PKM2 mutant - C326S To Be Published
9F4M	UP1 in complex with Z1401276297 Descriptor: (5~{R})-7-pyrazin-2-yl-2-oxa-7-azaspiro[4.4]nonane, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-28 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (1.39 Å) Cite: Enhanced identification of small molecules binding to hnRNP A1 via in silico hotspot and cryptic pockets mapping coupled with X-Ray fragment screening To Be Published
8CLK	TFIIIC TauA complex Descriptor: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 3, General transcription factor 3C polypeptide 5, ... Authors: Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. Deposit date: 2023-02-16 Release date: 2023-06-21 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
8CLJ	TFIIIC TauB-DNA dimer Descriptor: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... Authors: Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. Deposit date: 2023-02-16 Release date: 2023-06-21 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
8CLL	Structural insights into human TFIIIC promoter recognition Descriptor: General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... Authors: Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. Deposit date: 2023-02-16 Release date: 2023-06-21 Last modified: 2023-12-20 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
8CLI	TFIIIC TauB-DNA monomer Descriptor: DNA (35-MER), General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, ... Authors: Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. Deposit date: 2023-02-16 Release date: 2023-06-21 Last modified: 2023-07-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural insights into human TFIIIC promoter recognition. Sci Adv, 9, 2023
6R93	Cryo-EM structure of NCP-6-4PP Descriptor: Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... Authors: Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. Deposit date: 2019-04-02 Release date: 2019-06-12 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (4 Å) Cite: DNA damage detection in nucleosomes involves DNA register shifting. Nature, 571, 2019
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Cretu, C, Schmitzova, J, Pena, V. Deposit date: 2023-02-07 Release date: 2023-05-10 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Structural basis of catalytic activation in human splicing. Nature, 617, 2023
7CRG	Beta-strand-mediated dimeric formation of the extended Ig-like domains of human lamin A/C Descriptor: Prelamin-A/C Authors: Ahn, J, Ha, N.C. Deposit date: 2020-08-13 Release date: 2021-08-25 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Beta-strand-mediated dimeric formation of the Ig-like domains of human lamin A/C and B1. Biochem.Biophys.Res.Commun., 550, 2021
7D9N	Crystal structure of a non-canonic progeria mutation S143F at lamin A/C and its structural implication to the premature aging Descriptor: Lamin-A/C Authors: Ahn, J, Jung, S, Ha, N. Deposit date: 2020-10-14 Release date: 2021-11-17 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Crystal structure of progeria mutant S143F lamin A/C reveals increased hydrophobicity driving nuclear deformation. Commun Biol, 5, 2022
7CPV	Cryo-EM structure of 80S ribosome from mouse testis Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... Authors: Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. Deposit date: 2020-08-08 Release date: 2022-02-02 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.03 Å) Cite: A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
7K0Y	Cryo-EM structure of activated-form DNA-PK (complex VI) Descriptor: DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... Authors: Chen, X, Gellert, M, Yang, W. Deposit date: 2020-09-06 Release date: 2021-01-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
8QZS	Cryo-EM structure of the cross-exon B-like complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-29 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
8R0B	Cryo-EM structure of the cross-exon pre-B+ATP complex Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-31 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
8QPK	Cryo-EM Structure of Pre-B+5'ss Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-02 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
8QOZ	Cryo-EM Structure of Pre-B+5'ss+ATPgammaS Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss RNA oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-09-29 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
8QPB	Cryo-EM Structure of Pre-B+ATP Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-01 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
8QPA	Cryo-EM Structure of Pre-B+5'ssLNG Complex (core part) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... Authors: Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. Deposit date: 2023-10-01 Release date: 2024-05-22 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 2024
7K1N	CryoEM structure of inactivated-form DNA-PK (Complex V) Descriptor: DNA (5'-D(P*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(P*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... Authors: Chen, X, Gellert, M, Yang, W. Deposit date: 2020-09-08 Release date: 2021-01-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
7K1J	CryoEM structure of inactivated-form DNA-PK (Complex III) Descriptor: DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... Authors: Chen, X, Gellert, M, Yang, W. Deposit date: 2020-09-07 Release date: 2021-01-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
7K1K	CryoEM structure of inactivated-form DNA-PK (Complex IV) Descriptor: DNA (5'-D(*AP*AP*GP*CP*AP*GP*TP*AP*GP*AP*GP*CP*A)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*CP*TP*CP*TP*AP*CP*TP*GP*CP*TP*TP*CP*GP*AP*TP*AP*TP*CP*G)-3'), DNA-dependent protein kinase catalytic subunit, ... Authors: Chen, X, Gellert, M, Yang, W. Deposit date: 2020-09-07 Release date: 2021-01-06 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structure of an activated DNA-PK and its implications for NHEJ. Mol.Cell, 81, 2021
7EVO	The cryo-EM structure of the human 17S U2 snRNP Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... Authors: Zhang, X, Zhan, X, Shi, Y. Deposit date: 2021-05-21 Release date: 2022-08-03 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural insights into branch site proofreading by human spliceosome. Nat.Struct.Mol.Biol., 2024
7KW7	Atomic cryoEM structure of Hsp90-Hsp70-Hop-GR Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glucocorticoid receptor, Heat shock 70 kDa protein 1A, ... Authors: Wang, R.Y, Noddings, C.M, Kirschke, E, Myasnikov, A, Johnson, J.L, Agard, D.A. Deposit date: 2020-11-30 Release date: 2021-12-08 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Nature, 601, 2022
2RO1	NMR Solution Structures of Human KAP1 PHD finger-bromodomain Descriptor: Transcription intermediary factor 1-beta, ZINC ION Authors: Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J. Deposit date: 2008-03-04 Release date: 2008-05-20 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing Nat.Struct.Mol.Biol., 15, 2008

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