4DE8
 
 | | LytR-Cps2a-Psr family protein with bound octaprenyl monophosphate lipid | | Descriptor: | (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate, Cps2A, DI(HYDROXYETHYL)ETHER | | Authors: | Eberhardt, A, Hoyland, C.N, Vollmer, D.V, Bisle, S, Cleverley, R.M, Johnsborg, O, Havarstein, L.S, Lewis, R.J, Vollmer, W. | | Deposit date: | 2012-01-20 | | Release date: | 2012-04-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae.
Microb Drug Resist, 18, 2012
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3QPB
 | | Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily | | Descriptor: | 1-O-phosphono-alpha-D-ribofuranose, URACIL, Uridine phosphorylase | | Authors: | Tran, T.H, Christoffersen, S, Parker, W.B, Piskur, J, Serra, I, Terreni, M, Ealick, S.E. | | Deposit date: | 2011-02-11 | | Release date: | 2011-08-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011
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2POK
 | | Crystal structure of a M20 family metallo peptidase from Streptococcus pneumoniae | | Descriptor: | MANGANESE (II) ION, Peptidase, M20/M25/M40 family, ... | | Authors: | Minasov, G, Shuvalova, L, Brunzelle, J.S, Vorontsov, I.I, Kiryukhina, O, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-04-26 | | Release date: | 2007-05-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a M20 family metallo peptidase from Streptococcus pneumoniae.
TO BE PUBLISHED
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2PQV
 | | Crystal structure of MutT/nudix family protein from Streptococcus pneumoniae | | Descriptor: | MutT/nudix family protein, PHOSPHATE ION | | Authors: | Chang, C, Binkowski, T.A, Zhou, M, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2007-05-02 | | Release date: | 2007-06-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Crystal structure of MutT/nudix family protein from Streptococcus pneumoniae.
To be Published
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7S51
 | | Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATA peptide | | Descriptor: | LEU-PRO-ALA-THR-ALA, Sortase | | Authors: | Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-09-09 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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7S4O
 | | Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATS peptide | | Descriptor: | LEU-PRO-ALA-THR-SER-GLY, Sortase | | Authors: | Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-09-09 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.396 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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3FB9
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6PHV
 | | SpAga galactose product complex structure | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-galactosidase, ... | | Authors: | Pluvinage, B, Boraston, A.B. | | Deposit date: | 2019-06-25 | | Release date: | 2019-10-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
J.Biol.Chem., 294, 2019
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7SAF
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7SAY
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6BBT
 | | Structure of the major pilin protein (T-13) from Streptococcus pyogenes serotype GAS131465 | | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Young, P.G, Baker, E.N, Moreland, N.J. | | Deposit date: | 2017-10-19 | | Release date: | 2018-10-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
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5TT4
 | | Determining the Molecular Basis For Starter Unit Selection During Daunorubicin Biosynthesis | | Descriptor: | Daunorubicin-doxorubicin polyketide synthase | | Authors: | Jackson, D.R, Valentic, T.R, Patel, A, Tsai, S.C, Mohammed, L, Vasilakis, K, Wattana-amorn, P, Long, P.F, Crump, M.P, Crosby, J. | | Deposit date: | 2016-11-01 | | Release date: | 2016-11-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Determining the Molecular Basis For Starter Unit Selection During Daunorubicin Biosynthesis
To Be Published
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7PKJ
 | | Streptococcus pyogenes apo GapN | | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, ... | | Authors: | Schindelin, H, Albert, L. | | Deposit date: | 2021-08-25 | | Release date: | 2022-03-16 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.989 Å) | | Cite: | The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in Streptococcus pyogenes.
Front Microbiol, 13, 2022
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7PKC
 | | Streptococcus pyogenes Apo-GapN C284S variant | | Descriptor: | GLYCEROL, Putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | | Authors: | Schindelin, H, Albert, L. | | Deposit date: | 2021-08-25 | | Release date: | 2022-03-16 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in Streptococcus pyogenes.
Front Microbiol, 13, 2022
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6PHY
 | | SpAga D472N structure in complex alpha 1,3 galactobiose | | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... | | Authors: | Pluvinage, B, Boraston, A.B. | | Deposit date: | 2019-06-25 | | Release date: | 2019-10-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
J.Biol.Chem., 294, 2019
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3STR
 | | Strep Peptide Deformylase with a time dependent thiazolidine hydroxamic acid | | Descriptor: | (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-[2-(hydroxyamino)-2-oxoethyl]-1,3-thiazolidine-4-carboxamide, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Campobasso, N, Ward, P. | | Deposit date: | 2011-07-11 | | Release date: | 2011-07-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.
Biochemistry, 50, 2011
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6PHW
 | | SpAga D472N structure in complex with melibiose | | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID, ... | | Authors: | Pluvinage, B, Boraston, A.B. | | Deposit date: | 2019-06-25 | | Release date: | 2019-10-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
J.Biol.Chem., 294, 2019
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5UDN
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6PHU
 | | SpAga wild type apo structure | | Descriptor: | 1,2-ETHANEDIOL, Alpha-galactosidase, L(+)-TARTARIC ACID | | Authors: | Pluvinage, B, Boraston, A.B. | | Deposit date: | 2019-06-25 | | Release date: | 2019-10-02 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Molecular analysis of an enigmaticStreptococcus pneumoniaevirulence factor: The raffinose-family oligosaccharide utilization system.
J.Biol.Chem., 294, 2019
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3GUV
 | | Crystal structure of a resolvase family site-specific recombinase from Streptococcus pneumoniae | | Descriptor: | Site-specific recombinase, resolvase family protein | | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Do, J, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2009-03-30 | | Release date: | 2009-04-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of a resolvase family site-specific recombinase from Streptococcus pneumoniae
To be Published
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5U8K
 | | RitR mutant - C128S | | Descriptor: | Response regulator | | Authors: | Silvaggi, N.R, Han, L. | | Deposit date: | 2016-12-14 | | Release date: | 2017-12-20 | | Last modified: | 2018-11-28 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization.
PLoS Pathog., 14, 2018
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6PI0
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5UDM
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6BBW
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3TFL
 | | LytR-Cps2a-Psr family protein with bound octaprenyl pyrophosphate lipid | | Descriptor: | (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, CPS2A, ... | | Authors: | Kawai, Y, Marles-Wright, J, Cleverley, R.M, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Khai Bui, N, Hoyland, C.N, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J. | | Deposit date: | 2011-08-16 | | Release date: | 2011-10-12 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | A widespread family of bacterial cell wall assembly proteins.
Embo J., 30, 2011
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