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1C6T
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T4 LYSOZYME MUTANT C54T/C97A IN THE PRESENCE OF 8 ATM XENON
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (LYSOZYME), ...
Authors:Quillin, M.L, Matthews, B.W.
Deposit date:1999-12-21
Release date:2000-10-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Size versus polarizability in protein-ligand interactions: binding of noble gases within engineered cavities in phage T4 lysozyme.
J.Mol.Biol., 302, 2000
1C6V
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SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
Descriptor: PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE)
Authors:Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C.
Deposit date:1999-12-21
Release date:2000-12-27
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
1C6W
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MAUROCALCIN FROM SCORPIO MAURUS
Descriptor: MAUROCALCIN
Authors:Mosbah, A, Kharrat, R, Fajloun, Z, Renisio, J.-G, Blanc, E, Sabatier, J.-M, Ayeb, M, Darbon, H.
Deposit date:1999-12-23
Release date:2000-09-06
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:A new fold in the scorpion toxin family, associated with an activity on a ryanodine-sensitive calcium channel.
Proteins, 40, 2000
1C6X
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ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(S)-CYCLOPENTYL-1(R)-HYDROXY-3(R)METHYL]-5-[(2(S)-TERTIARY-BUTYLAMINO-CARBONYL)-4-(N1-(2)-(N-METHYLPIPERAZINYL)-3-CHLORO-PYRAZINYL-5-CARBONYL)-PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYL-PENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C6Y
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ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C6Z
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ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-28
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C70
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ALTERNATE BINDING SITE FOR THE P1-P3 GROUP OF A CLASS OF POTENT HIV-1 PROTEASE INHIBITORS AS A RESULT OF CONCERTED STRUCTURAL CHANGE IN 80'S LOOP.
Descriptor: N-[2(R)-HYDROXY-1(S)-INDANYL]-2(R)-PHENYLMETHYL-4(S)-HYDROXY-5-[4-[2-BENZOFURANYLMETHYL]-2(S)-[TERT-BUTYLAMINOCARBONYL]-PIPERAZINYL]-PENTANEAMIDE, PROTEIN (PROTEASE)
Authors:Munshi, S.
Deposit date:1999-12-29
Release date:2000-12-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Acta Crystallogr.,Sect.D, 56, 2000
1C72
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TYR115, GLN165 AND TRP209 CONTRIBUTE TO THE 1,2-EPOXY-3-(P-NITROPHENOXY)PROPANE CONJUGATING ACTIVITIES OF GLUTATHIONE S-TRANSFERASE CGSTM1-1
Descriptor: 1-HYDROXY-2-S-GLUTATHIONYL-3-PARA-NITROPHENOXY-PROPANE, PROTEIN (GLUTATHIONE S-TRANSFERASE)
Authors:Chern, M.K, Wu, T.C, Hsieh, C.H, Chou, C.C, Liu, L.F, Kuan, I.C, Yeh, Y.H, Hsiao, C.D, Tam, M.F.
Deposit date:2000-02-02
Release date:2000-08-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.
J.Mol.Biol., 300, 2000
1C74
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Structure of the double mutant (K53,56M) of phospholipase A2
Descriptor: CALCIUM ION, PHOSPHOLIPASE A2
Authors:Sekar, K, Tsai, M.D, Jain, M.K, Ramakumar, S.
Deposit date:2000-01-22
Release date:2000-07-22
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of the anionic interface preference and k*cat activation of pancreatic phospholipase A2.
Biochemistry, 39, 2000
1C75
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0.97 A "AB INITIO" CRYSTAL STRUCTURE OF CYTOCHROME C-553 FROM BACILLUS PASTEURII
Descriptor: CYTOCHROME C-553, HEME C
Authors:Benini, S, Ciurli, S, Rypniewski, W.R, Wilson, K.S.
Deposit date:2000-02-09
Release date:2000-03-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Crystal structure of oxidized Bacillus pasteurii cytochrome c553 at 0.97-A resolution.
Biochemistry, 39, 2000
1C76
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STAPHYLOKINASE (SAK) MONOMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Staphylokinase Dimer Offers New Clue to Reduction of Immunogenicity
To be published
1C77
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STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C78
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STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C79
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STAPHYLOKINASE (SAK) DIMER
Descriptor: STAPHYLOKINASE
Authors:Rao, Z, Jiang, F, Liu, Y, Zhang, X, Chen, Y, Bartlam, M, Song, H, Ding, Y.
Deposit date:2000-02-01
Release date:2000-08-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a staphylokinase: variant a model for reduced antigenicity.
Eur.J.Biochem., 269, 2002
1C7B
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DEOXY RHB1.0 (RECOMBINANT HEMOGLOBIN)
Descriptor: PROTEIN (DEOXYHEMOGLOBIN (ALPHA CHAIN)), PROTEIN (DEOXYHEMOGLOBIN (BETA CHAIN)), PROTOPORPHYRIN IX CONTAINING FE
Authors:Brucker, E.A.
Deposit date:2000-02-09
Release date:2000-06-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:Genetically crosslinked hemoglobin: a structural study.
Acta Crystallogr.,Sect.D, 56, 2000
1C7C
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DEOXY RHB1.1 (RECOMBINANT HEMOGLOBIN)
Descriptor: PROTEIN (DEOXYHEMOGLOBIN (ALPHA CHAIN)), PROTEIN (DEOXYHEMOGLOBIN (BETA CHAIN)), PROTOPORPHYRIN IX CONTAINING FE
Authors:Brucker, E.A.
Deposit date:2000-02-09
Release date:2000-06-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Genetically crosslinked hemoglobin: a structural study.
Acta Crystallogr.,Sect.D, 56, 2000
1C7D
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DEOXY RHB1.2 (RECOMBINANT HEMOGLOBIN)
Descriptor: PROTEIN (DEOXYHEMOGLOBIN (ALPHA CHAIN)), PROTEIN (DEOXYHEMOGLOBIN (BETA CHAIN)), PROTOPORPHYRIN IX CONTAINING FE
Authors:Brucker, E.A.
Deposit date:2000-02-09
Release date:2000-06-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Genetically crosslinked hemoglobin: a structural study.
Acta Crystallogr.,Sect.D, 56, 2000
1C7E
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D95E HYDROQUINONE FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
Authors:McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D.
Deposit date:2000-02-16
Release date:2000-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin
Biochemistry, 41, 2002
1C7F
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D95E OXIDIZED FLAVODOXIN MUTANT FROM D. VULGARIS
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVODOXIN
Authors:McCarthy, A, Walsh, M, Higgins, T, D'Arcy, D.
Deposit date:2000-02-11
Release date:2000-08-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic Investigation of the Role of Aspartate 95 in the Modulation of the Redox Potentials Of Desulfovibrio Vulgaris Flavodoxin
Biochemistry, 41, 2002
1C7G
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TYROSINE PHENOL-LYASE FROM ERWINIA HERBICOLA
Descriptor: PYRIDOXAL-5'-PHOSPHATE, TYROSINE PHENOL-LYASE
Authors:Mikami, B, Yamamoto, Y, Katayama, T, Suzuki, H.
Deposit date:2000-02-18
Release date:2003-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of Tyrosine Phenol-Lyase from Erwinia Herbicola
To be Published
1C7H
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CRYSTAL STRUCTURE OF A MUTANT R75A IN KETOSTEROID ISOMERASE FROM PSEDOMONAS PUTIDA BIOTYPE B
Descriptor: DELTA-5-3-KETOSTEROID ISOMERASE
Authors:Nam, G.H, Kim, D.H, Jang, D.S, Choi, G, Ha, N.C, Oh, B.H, Choi, K.Y.
Deposit date:2000-02-19
Release date:2000-04-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
Biochemistry, 38, 1999
1C7I
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THERMOPHYLIC PNB ESTERASE
Descriptor: CALCIUM ION, PROTEIN (PARA-NITROBENZYL ESTERASE)
Authors:Spiller, B, Gershenson, A, Arnold, F, Stevens, R.
Deposit date:2000-02-21
Release date:2000-03-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A structural view of evolutionary divergence.
Proc.Natl.Acad.Sci.USA, 96, 1999
1C7J
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PNB ESTERASE 56C8
Descriptor: POTASSIUM ION, PROTEIN (PARA-NITROBENZYL ESTERASE), SULFATE ION
Authors:Spiller, B, Gershenson, A, Arnold, F, Stevens, R.C.
Deposit date:2000-02-21
Release date:2000-03-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A structural view of evolutionary divergence.
Proc.Natl.Acad.Sci.USA, 96, 1999
1C7K
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CRYSTAL STRUCTURE OF THE ZINC PROTEASE
Descriptor: CALCIUM ION, ZINC ENDOPROTEASE, ZINC ION
Authors:Kurisu, G, Harada, S, Kai, Y.
Deposit date:2000-02-19
Release date:2001-04-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structure of the zinc-binding site in the crystal structure of a zinc endoprotease from Streptomyces caespitosus at 1 A resolution.
J.Inorg.Biochem., 82, 2000
1C7M
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SOLUTION STRUCTURE OF THE FUNCTIONAL DOMAIN OF PARACOCCUS DENITRIFICANS CYTOCHROME C552 IN THE REDUCED STATE
Descriptor: HEME C, PROTEIN (CYTOCHROME C552)
Authors:Pristovsek, P, Luecke, C, Reincke, B, Ludwig, B, Rueterjans, H.
Deposit date:2000-03-03
Release date:2000-07-19
Last modified:2024-10-30
Method:SOLUTION NMR
Cite:Solution structure of the functional domain of Paracoccus denitrificans cytochrome c552 in the reduced state.
Eur.J.Biochem., 267, 2000

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數據於2024-10-30公開中

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