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7QR3
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Chimpanzee CPEB3 HDV-like ribozyme
Descriptor: GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ...
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-10
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
7QR4
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human CPEB3 HDV-like ribozyme
Descriptor: RNA CPEB3 ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O.
Deposit date:2022-01-17
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes
Biorxiv, 2022
7Q8A
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BU of 7q8a by Molmil
Crystal structure of tandem domain RRM1-2 of FUBP-interacting repressor (FIR) bound to FUSE ssDNA fragment
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*GP*T)-3'), Poly(U)-binding-splicing factor PUF60, ...
Authors:Ni, X, Joerger, A.C, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2021-11-10
Release date:2022-11-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of tandem domain RRM1-2 of FIR bound to FUSE ssDNA fragment
To Be Published
7QDD
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NMR structure of Npl3 RRM1 bound to the AUCCAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3')
Authors:Clery, A, Allain, F.H.-T, Moursy, A.
Deposit date:2021-11-26
Release date:2022-10-26
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
7QDE
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NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA
Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*GP*UP*GP*GP*AP*A)-3')
Authors:Allain, F.H.-T, Clery, A, Moursy, A.
Deposit date:2021-11-26
Release date:2022-12-21
Last modified:2024-01-10
Method:SOLUTION NMR
Cite:RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing.
Nat Commun, 14, 2023
7QZP
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Identification and characterization of an RRM-containing, ELAV-like, RNA binding protein in Acinetobacter Baumannii
Descriptor: Hypothetical RNA binding protein from Acinetobacter baumannii
Authors:Ciani, C, Perez-Rafols, A, Bonomo, I, Micaelli, M, Esposito, A, Zucal, C, Belli, R, D'Agostino, V.G, Bianconi, I, Calderone, V, Cerofolini, L, Fragai, M, Provenzani, A.
Deposit date:2022-01-31
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii .
Biomolecules, 12, 2022
7S3B
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Crystal structure of intact U2AF65 RRM-region bound to AdML-G5 oligonucleotide
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*GP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3A
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Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3C
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BU of 7s3c by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Glasser, E, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
2MZS
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BU of 2mzs by Molmil
NMR structure of the RRM2 domain of Hrb1
Descriptor: Protein HRB1
Authors:Martinez-Lumbreras, S, Seraphin, B, Perez-Canadillas, J.
Deposit date:2015-02-23
Release date:2015-12-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Gbp2 interacts with THO/TREX through a novel type of RRM domain.
Nucleic Acids Res., 44, 2016
2MPU
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BU of 2mpu by Molmil
Structural and Functional analysis of the Hordeum vulgare L. HvGR-RBP1 protein, a glycine-rich RNA binding protein implicated in the regulation of barley leaf senescence and environmental adaptation
Descriptor: RBP1
Authors:Mason, K.E, Tripet, B.P, Eilers, B.J, Powell, P, Fischer, A.M, Copie, V.
Deposit date:2014-06-02
Release date:2014-12-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural and Biochemical Analysis of the Hordeum vulgare L. HvGR-RBP1 Protein, a Glycine-Rich RNA-Binding Protein Involved in the Regulation of Barley Plant Development and Stress Response.
Biochemistry, 53, 2014
5W0H
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Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
2MY2
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BU of 2my2 by Molmil
Snu17p-Bud13p structure intermediate during RES complex assembly
Descriptor: Pre-mRNA-splicing factor CWC26, U2 snRNP component IST3
Authors:Wysoczanski, P, Becker, S, Zweckstetter, M.
Deposit date:2015-01-19
Release date:2015-08-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of intermediates during RES complex assembly.
Sci Rep, 5, 2015
2O3D
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BU of 2o3d by Molmil
Structure of human SF2/ASF RNA recognition motif 2 (RRM2)
Descriptor: Splicing factor, arginine/serine-rich 1
Authors:Tintaru, A.M, Hautbergue, G.M, Hounslow, A.M, Lian, L.Y, Craven, C.J, Wilson, S.A.
Deposit date:2006-12-01
Release date:2007-10-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural and functional analysis of RNA and TAP binding to SF2/ASF.
Embo Rep., 8, 2007
5W0G
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BU of 5w0g by Molmil
Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ...
Authors:Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2017-05-30
Release date:2018-04-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs.
Biochemistry, 56, 2017
2OIH
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BU of 2oih by Molmil
Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+
Descriptor: HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-11
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
2NZ4
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BU of 2nz4 by Molmil
Structural investigation of the GlmS ribozyme bound to its catalytic cofactor
Descriptor: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GlmS ribozyme, MAGNESIUM ION, ...
Authors:Cochrane, J.C.
Deposit date:2006-11-22
Release date:2007-01-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Structural Investigation of the GlmS Ribozyme Bound to Its Catalytic Cofactor
Chem.Biol., 14, 2007
2OJ3
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BU of 2oj3 by Molmil
Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+)
Descriptor: COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ...
Authors:Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A.
Deposit date:2007-01-12
Release date:2007-03-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
5WWF
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BU of 5wwf by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWG
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BU of 5wwg by Molmil
Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
5WWE
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BU of 5wwe by Molmil
Crystal structure of hnRNPA2B1 in complex with RNA
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3')
Authors:Wu, B.X, Su, S.C, Ma, J.B.
Deposit date:2017-01-01
Release date:2018-01-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
2OSR
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BU of 2osr by Molmil
NMR Structure of RRM-2 of Yeast NPL3 Protein
Descriptor: Nucleolar protein 3
Authors:Deka, P, Bucheli, M, Skrisovska, L, Allain, F.H, Moore, C, Buratowski, S, Varani, G.
Deposit date:2007-02-06
Release date:2007-12-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals.
J.Mol.Biol., 375, 2008
2PEH
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BU of 2peh by Molmil
Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5
Descriptor: Splicing factor 3B subunit 1, Splicing factor 45
Authors:Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
Deposit date:2007-04-03
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007
5X3Z
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BU of 5x3z by Molmil
Solution structure of musashi1 RBD2 in complex with RNA
Descriptor: RNA (5'-R(*GP*UP*AP*GP*U)-3'), RNA-binding protein Musashi homolog 1
Authors:Iwaoka, R, Nagata, T, Tsuda, K, Imai, T, Okano, H, Kobayashi, N, Katahira, M.
Deposit date:2017-02-09
Release date:2017-12-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA
Molecules, 22, 2017
2PE8
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Crystal structure of the UHM domain of human SPF45 (free form)
Descriptor: Splicing factor 45
Authors:Corsini, L, Basquin, J, Hothorn, M, Sattler, M.
Deposit date:2007-04-02
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:U2AF-homology motif interactions are required for alternative splicing regulation by SPF45.
Nat.Struct.Mol.Biol., 14, 2007

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數據於2024-06-05公開中

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