8BHJ
 
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8BF7
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8BGH
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8BIM
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8BIL
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8BSI
 | | Giardia ribosome chimeric hybrid-like GDP+Pi bound state (B1) | | Descriptor: | 40S ribosomal protein S21, 40S ribosomal protein S25, 40S ribosomal protein S26, ... | | Authors: | Majumdar, S, Emmerich, A.G, Sanyal, S. | | Deposit date: | 2022-11-25 | | Release date: | 2023-03-15 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.
Nucleic Acids Res., 51, 2023
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8BA0
 | | Drosophila melanogaster complex I in the Twisted state (Dm2) | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Acyl carrier protein, ... | | Authors: | Agip, A.N.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | Deposit date: | 2022-10-10 | | Release date: | 2023-01-18 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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8BPX
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition) | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | Authors: | Klusch, N, Kuehlbrandt, W. | | Deposit date: | 2022-11-18 | | Release date: | 2023-01-25 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (2.09 Å) | | Cite: | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8B9Z
 | | Drosophila melanogaster complex I in the Active state (Dm1) | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Agip, A.A, Chung, I, Sanchez-Martinez, A, Whitworth, A.J, Hirst, J. | | Deposit date: | 2022-10-10 | | Release date: | 2023-01-18 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
Elife, 12, 2023
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8B7Y
 | | Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Koller, T.O, Graf, M, Wilson, D.N. | | Deposit date: | 2022-10-03 | | Release date: | 2023-01-25 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
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8BIP
 | | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | | Deposit date: | 2022-11-02 | | Release date: | 2023-02-08 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
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8BJQ
 | | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | | Descriptor: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | Authors: | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | | Deposit date: | 2022-11-05 | | Release date: | 2023-02-08 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains.
Plos Biol., 21, 2023
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7ZW0
 | | FAP-80S Complex - Rotated state | | Descriptor: | 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ... | | Authors: | Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R. | | Deposit date: | 2022-05-17 | | Release date: | 2022-10-05 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
Mol.Cell, 82, 2022
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7ZJW
 | | Rabbit 80S ribosome as it decodes the Sec-UGA codon | | Descriptor: | 18S rRNA, 28S rRNA, 40S Ribosomal protein eS19, ... | | Authors: | Hilal, T, Simonovic, M, Spahn, C.M.T. | | Deposit date: | 2022-04-12 | | Release date: | 2022-10-19 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Science, 376, 2022
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8BF9
 | | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. | | Descriptor: | 60S ribosomal protein L39, Large ribosomal subunit protein eL31, Large ribosomal subunit protein eL38, ... | | Authors: | Karki, S, Javanainen, M, Tranter, D, Rehan, S, Huiskonen, J, Happonen, L, Paavilainen, V. | | Deposit date: | 2022-10-24 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.
Embo Rep., 24, 2023
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8BN3
 | | Yeast 80S, ES7s delta, eIF5A, Stm1 containing | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | | Authors: | Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N. | | Deposit date: | 2022-11-12 | | Release date: | 2024-01-10 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes.
Nucleic Acids Res., 52, 2024
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8CRX
 | | Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound | | Descriptor: | 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Lomakin, I.B, Devarkar, S.C, Bunick, C.G. | | Deposit date: | 2022-05-12 | | Release date: | 2023-03-22 | | Last modified: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
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3W9Z
 | | Crystal structure of DusC | | Descriptor: | FLAVIN MONONUCLEOTIDE, tRNA-dihydrouridine synthase C | | Authors: | Chen, M, Yu, J, Tanaka, Y, Tanaka, I, Yao, M. | | Deposit date: | 2013-04-19 | | Release date: | 2013-07-31 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of dihydrouridine synthase C (DusC) from Escherichia coli
Acta Crystallogr.,Sect.F, 69, 2013
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4XP7
 | | Crystal structure of Human tRNA dihydrouridine synthase 2 | | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like | | Authors: | Whelan, F, Jenkins, H.T, Griffiths, S, Byrne, R.T, Dodson, E.J, Antson, A.A. | | Deposit date: | 2015-01-16 | | Release date: | 2015-01-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | From bacterial to human dihydrouridine synthase: automated structure determination.
Acta Crystallogr.,Sect.D, 71, 2015
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4BF9
 | | Crystal structure of E. coli dihydrouridine synthase C (DusC) (selenomethionine derivative) | | Descriptor: | FLAVIN MONONUCLEOTIDE, TRNA-DIHYDROURIDINE SYNTHASE C | | Authors: | Byrne, R.T, Whelan, F, Konevega, A, Aziz, N, Rodnina, M, Antson, A.A. | | Deposit date: | 2013-03-16 | | Release date: | 2013-11-06 | | Last modified: | 2015-05-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4BFA
 | | Crystal structure of E. coli dihydrouridine synthase C (DusC) | | Descriptor: | 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NITRATE ION, ... | | Authors: | Byrne, R.T, Whelan, F, Konevega, A, Aziz, N, Rodnina, M, Antson, A.A. | | Deposit date: | 2013-03-16 | | Release date: | 2013-11-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Major Reorientation of tRNA Substrates Defines Specificity of Dihydrouridine Synthases.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6EI9
 | | Crystal structure of E. coli tRNA-dihydrouridine synthase B (DusB) | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | Authors: | Bou-Nader, C, Hamdane, D. | | Deposit date: | 2017-09-18 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Unveiling structural and functional divergences of bacterial tRNA dihydrouridine synthases: perspectives on the evolution scenario.
Nucleic Acids Res., 46, 2018
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6EZA
 | | Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant | | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D. | | Deposit date: | 2017-11-14 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
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6EZB
 | | Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant | | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ... | | Authors: | Bou-Nader, C, Bregeon, D, Pecqueur, L, Fontecave, M, Hamdane, D. | | Deposit date: | 2017-11-14 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
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6EZC
 | | Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant | | Descriptor: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | Authors: | Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D. | | Deposit date: | 2017-11-14 | | Release date: | 2018-09-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
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