5HLK
| Crystal structure of the ternary EcoRV-DNA-Lu complex with cleaved DNA substrate. | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP)-3'), DNA (5'-D(*AP*TP*CP*TP*TP*TP)-3'), ... | Authors: | Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L. | Deposit date: | 2016-01-15 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016
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2RVE
| THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA SEGMENTS | Descriptor: | DNA (5'-D(*CP*GP*AP*GP*CP*TP*CP*G)-3'), PROTEIN (ECO RV (E.C.3.1.21.4)) | Authors: | Winkler, F.K, Banner, D.W, Oefner, C, Tsernoglou, D, Brown, R.S, Heathman, S.P, Bryan, R.K, Martin, P.D, Petratos, K, Wilson, K.S. | Deposit date: | 1991-03-19 | Release date: | 1992-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments. EMBO J., 12, 1993
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5F8A
| Crystal structure of the ternary EcoRV-DNA-Lu complex with uncleaved DNA substrate. Lanthanide binding to EcoRV-DNA complex inhibits cleavage. | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*T)-3'), LUTETIUM (III) ION, ... | Authors: | Sangani, S.S, Kehr, A.D, Sinha, K, Rule, G.S, Jen-Jacobson, L. | Deposit date: | 2015-12-09 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Metal Ion Binding at the Catalytic Site Induces Widely Distributed Changes in a Sequence Specific Protein-DNA Complex. Biochemistry, 55, 2016
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4RVE
| THE CRYSTAL STRUCTURE OF ECORV ENDONUCLEASE AND OF ITS COMPLEXES WITH COGNATE AND NON-COGNATE DNA SEGMENTS | Descriptor: | DNA (5'-D(*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), PROTEIN (ECO RV (E.C.3.1.21.4)) | Authors: | Winkler, F.K, Banner, D.W, Oefner, C, Tsernoglou, D, Brown, R.S, Heathman, S.P, Bryan, R.K, Martin, P.D, Petratos, K, Wilso, K.S. | Deposit date: | 1993-02-18 | Release date: | 1993-04-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of EcoRV endonuclease and of its complexes with cognate and non-cognate DNA fragments. EMBO J., 12, 1993
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2GE5
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2B0D
| EcoRV Restriction Endonuclease/GAATTC/Ca2+ | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*AP*TP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV | Authors: | Hiller, D.A, Rodriguez, A.M, Perona, J.J. | Deposit date: | 2005-09-13 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC J.Mol.Biol., 354, 2005
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2B0E
| EcoRV Restriction Endonuclease/GAAUTC/Ca2+ | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*AP*(DU)P*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV | Authors: | Hiller, D.A, Rodriguez, A.M, Perona, J.J. | Deposit date: | 2005-09-13 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC J.Mol.Biol., 354, 2005
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1SUZ
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1STX
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1SX5
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1SX8
| EcoRV bound to cognate DNA and Mn2+ | Descriptor: | 5'-D(*C*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', MANGANESE (II) ION, Type II restriction enzyme EcoRV | Authors: | Horton, N.C, Perona, J.J. | Deposit date: | 2004-03-30 | Release date: | 2004-04-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | DNA Cleavage by EcoRV Endonuclease: Two Metal Ions in Three Metal Ion Binding Sites Biochemistry, 43, 2004
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1EO3
| INHIBITION OF ECORV ENDONUCLEASE BY DEOXYRIBO-3'-S-PHOSPHOROTHIOLATES: A HIGH RESOLUTION X-RAY CRYSTALLOGRAPHIC STUDY | Descriptor: | ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MAGNESIUM ION, ... | Authors: | Horton, N.C, Connolly, B.A, Perona, J.J. | Deposit date: | 2000-03-21 | Release date: | 2000-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
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1EO4
| ECORV BOUND TO MN2+ AND COGNATE DNA CONTAINING A 3'S SUBSTITION AT THE CLEAVAGE SITE | Descriptor: | ACETIC ACID, DNA (5'-D(*CP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), MANGANESE (II) ION, ... | Authors: | Horton, N.C, Connolly, B.A, Perona, J.J. | Deposit date: | 2000-03-21 | Release date: | 2000-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
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1EOO
| ECORV BOUND TO COGNATE DNA | Descriptor: | DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV | Authors: | Horton, N.C, Perona, J.J. | Deposit date: | 2000-03-23 | Release date: | 2000-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystallographic snapshots along a protein-induced DNA-bending pathway. Proc.Natl.Acad.Sci.USA, 97, 2000
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1EOP
| ECORV BOUND TO COGNATE DNA | Descriptor: | DNA (5'-D(*GP*AP*AP*GP*AP*TP*AP*TP*CP*TP*TP*C)-3'), TYPE II RESTRICTION ENZYME ECORV | Authors: | Horton, N.C, Perona, J.J. | Deposit date: | 2000-03-23 | Release date: | 2000-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystallographic snapshots along a protein-induced DNA-bending pathway. Proc.Natl.Acad.Sci.USA, 97, 2000
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1RVE
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1RVB
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1RVA
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1EON
| ECORV BOUND TO 3'-S-PHOSPHOROTHIOLATE DNA AND CA2+ | Descriptor: | ACETIC ACID, CHLORIDE ION, DNA (5'-D(*AP*AP*AP*GP*AP*(TSP)P*AP*TP*CP*TP*T)-3'), ... | Authors: | Horton, N.C, Connolly, B.A, Perona, J.J. | Deposit date: | 2000-03-23 | Release date: | 2000-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Inhibition of EcoRV Endonuclease by Deoxyribo-3'-S-phosphorothiolates: A High-Resolution X-ray Crystallographic Study J.Am.Chem.Soc., 122, 2000
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1RVC
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1RV5
| COMPLEX OF ECORV ENDONUCLEASE WITH D(AAAGAT)/D(ATCTT) | Descriptor: | 5'-D(*AP*AP*AP*GP*AP*T*AP*TP*CP*TP*T)-3', ECORV ENDONUCLEASE | Authors: | Horton, N.C, Perona, J.J. | Deposit date: | 1998-06-01 | Release date: | 1998-11-11 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d(AAAGAT) + d(ATCTT). J.Mol.Biol., 277, 1998
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1AZ3
| ECORV ENDONUCLEASE, UNLIGANDED, FORM B | Descriptor: | ECORV ENDONUCLEASE | Authors: | Perona, J, Martin, A. | Deposit date: | 1997-11-24 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis. J.Mol.Biol., 273, 1997
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1B96
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1B97
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1BGB
| ECORV ENDONUCLEASE COMPLEX WITH 5'-CGGGATATCCC DNA | Descriptor: | DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), ECORV ENDONUCLEASE | Authors: | Perona, J, Horton, N.C. | Deposit date: | 1998-05-28 | Release date: | 1998-10-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts. J.Biol.Chem., 273, 1998
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