5JCV
 
 | | Sortase B from Listeria monocytogenes. | | Descriptor: | CHLORIDE ION, Lmo2181 protein, SULFATE ION | | Authors: | Osipiuk, J, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-04-15 | | Release date: | 2016-04-27 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Sortase B from Listeria monocytogenes.
to be published
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6R1V
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5K9A
 | | Sortase A from Corynebacterium diphtheriae | | Descriptor: | Putative fimbrial associated sortase-like protein, SULFATE ION | | Authors: | Osipiuk, J, Huang, I.-H, Ma, X, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-05-31 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking.
Proc.Natl.Acad.Sci.USA, 115, 2018
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7V6K
 | | Crystal structure of Sortase A from Streptococcus pyogenes in complex with ML346 | | Descriptor: | 5-[3-(4-methoxyphenyl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, MAGNESIUM ION, Sortase | | Authors: | Yang, C.G, Gan, J. | | Deposit date: | 2021-08-20 | | Release date: | 2021-12-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella.
Rsc Med Chem, 13, 2022
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4UX7
 | | Structure of a Clostridium difficile sortase | | Descriptor: | DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, PUTATIVE PEPTIDASE C60B, ... | | Authors: | Chambers, C.J, Roberts, A.K, Shone, C.C, Acharya, K.R. | | Deposit date: | 2014-08-19 | | Release date: | 2015-04-01 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure and Function of a Clostridium Difficile Sortase Enzyme.
Sci.Rep., 5, 2015
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4TQX
 | | Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone. | | Descriptor: | ACETIC ACID, SULFATE ION, Sortase, ... | | Authors: | Wallock-Richards, D.J, Marles-Wright, J, Clarke, D.J, Maitra, A, Dodds, M, Hanley, B, Campopiano, D.J. | | Deposit date: | 2014-06-12 | | Release date: | 2015-05-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone.
Chem.Commun.(Camb.), 51, 2015
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6IXZ
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5YFK
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1IJA
 | | Structure of Sortase | | Descriptor: | Sortase | | Authors: | Ilangovan, U, Ton-That, H, Iwahara, J, Schneewind, O, Clubb, R.T. | | Deposit date: | 2001-04-25 | | Release date: | 2001-05-09 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 98, 2001
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4LFD
 | | Staphylococcus aureus sortase B-substrate complex | | Descriptor: | (CBZ)NPQ(B27) PEPTIDE, SULFATE ION, Sortase B | | Authors: | Jacobitz, A.W, Sawaya, M.R, Yi, S.W, Amer, B.R, Huang, G.L, Nguyen, A.V, Jung, M.E, Clubb, R.T. | | Deposit date: | 2013-06-26 | | Release date: | 2014-02-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural and Computational Studies of the Staphylococcus aureus Sortase B-Substrate Complex Reveal a Substrate-stabilized Oxyanion Hole.
J.Biol.Chem., 289, 2014
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6BWE
 | | Sortase A from Corynebacterium diphtheriae, lid mutant | | Descriptor: | Putative fimbrial associated sortase-like protein | | Authors: | Osipiuk, J, Chang, C, Huang, I.H, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-12-14 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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2XWG
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6KYC
 | | Structure of the S207A mutant of Clostridium difficile sortase B | | Descriptor: | Putative peptidase C60B, sortase B | | Authors: | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | | Deposit date: | 2019-09-17 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020
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6KYD
 | | Structure of the R217A mutant of Clostridium difficile sortase B | | Descriptor: | Putative peptidase C60B, sortase B | | Authors: | Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y. | | Deposit date: | 2019-09-18 | | Release date: | 2020-02-19 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020
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4G1H
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7S51
 | | Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATA peptide | | Descriptor: | LEU-PRO-ALA-THR-ALA, Sortase | | Authors: | Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-09-09 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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7S4O
 | | Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATS peptide | | Descriptor: | LEU-PRO-ALA-THR-SER-GLY, Sortase | | Authors: | Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-09-09 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.396 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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7T8Y
 | | Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-in conformation | | Descriptor: | ACE-ALA-ZGL-LYS-DAL-DAL, BE2-LEU-PRO-ALA-THR-ALA-ALA, Sortase | | Authors: | Piper, I.M, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-12-17 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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4Y4Q
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7T8Z
 | | Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-out conformation | | Descriptor: | ACE-ALA-ZGL-LYS-DAL-DAL, BE2-LEU-PRO-ALA-THR-ALA-ALA, Sortase | | Authors: | Piper, I.M, Antos, J.M, Amacher, J.F. | | Deposit date: | 2021-12-17 | | Release date: | 2022-09-07 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
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4O8L
 | | Structure of sortase A from Streptococcus pneumoniae | | Descriptor: | Sortase | | Authors: | Misra, A, Biswas, T, Das, S, Marathe, U, Roy, R.P, Ramakumar, S. | | Deposit date: | 2013-12-28 | | Release date: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of sortase A from Streptococcus pneumoniae
To be Published
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4G1J
 | | Sortase C1 of GBS Pilus Island 1 | | Descriptor: | Sortase family protein | | Authors: | Cozzi, R, Prigozhin, D.M, Alber, T. | | Deposit date: | 2012-07-10 | | Release date: | 2012-12-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.
Plos One, 7, 2012
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5DV0
 | | Structure of S. pneumoniae D39 sortase A | | Descriptor: | Sortase SrtA | | Authors: | Deng, X. | | Deposit date: | 2015-09-21 | | Release date: | 2016-10-12 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.299 Å) | | Cite: | Structure of S. pneumoniae D39 Sortase A
To Be Published
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4D7W
 | | Crystal structure of sortase C1 (SrtC1) from Streptococcus agalactiae | | Descriptor: | 1,2-ETHANEDIOL, SORTASE FAMILY PROTEIN | | Authors: | Malito, E, Lazzarin, M, Cozzi, R, Bottomley, M.J. | | Deposit date: | 2014-11-28 | | Release date: | 2015-08-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Noncanonical Sortase-Mediated Assembly of Pilus Type 2B in Group B Streptococcus.
Faseb J., 29, 2015
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5UTT
 | | SrtA sortase from Actinomyces oris | | Descriptor: | CHLORIDE ION, Sortase | | Authors: | Osipiuk, J, Ma, X, Ton-That, H, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2017-02-15 | | Release date: | 2017-03-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Cell-to-cell interaction requires optimal positioning of a pilus tip adhesin modulated by gram-positive transpeptidase enzymes.
Proc.Natl.Acad.Sci.USA, 116, 2019
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