8I6N
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![BU of 8i6n by Molmil](/molmil-images/mine/8i6n) | Crystal structure of Co-type nitrile hydratase mutant from Pseudomonas thermophila - L6T | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Ma, D, Cheng, Z.Y, Lai, Q.P, Hou, X.D, Yin, D.J, Rao, Y.J, Zhou, Z.M. | Deposit date: | 2023-01-29 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of Co-type nitrile hydratase mutant L6T from Pseudomonas thermophila at 2.2 Angstroms resolution. To Be Published
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1IRE
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![BU of 1ire by Molmil](/molmil-images/mine/1ire) | Crystal Structure of Co-type nitrile hydratase from Pseudonocardia thermophila | Descriptor: | COBALT (II) ION, Nitrile Hydratase | Authors: | Miyanaga, A, Fushinobu, S, Ito, K, Wakagi, T. | Deposit date: | 2001-10-01 | Release date: | 2002-10-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of cobalt-containing nitrile hydratase. Biochem.Biophys.Res.Commun., 288, 2001
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7Z0V
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![BU of 7z0v by Molmil](/molmil-images/mine/7z0v) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | Descriptor: | CHLORIDE ION, COBALT (II) ION, Nitrile hydratase, ... | Authors: | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | Deposit date: | 2022-02-23 | Release date: | 2023-03-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase. Curr Res Struct Biol, 4, 2022
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3HHT
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![BU of 3hht by Molmil](/molmil-images/mine/3hht) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | Descriptor: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase alpha subunit, ... | Authors: | Van Wyk, J.C, Sewell, B.T, Cowan, D.A, Sayed, M.F, Tsekoa, T.L, Tastan Bishop, A.O. | Deposit date: | 2009-05-17 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | The high-resolution structure of a Cobalt containing nitrile hydratase To be published
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4FM4
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![BU of 4fm4 by Molmil](/molmil-images/mine/4fm4) | Wild Type Fe-type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit, ... | Authors: | Kuhn, M.L, Martinez, S, Gumataotao, N, Bornscheuer, U, Liu, D, Holz, R.C. | Deposit date: | 2012-06-15 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.384 Å) | Cite: | The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli. Biochem.Biophys.Res.Commun., 424, 2012
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1AHJ
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![BU of 1ahj by Molmil](/molmil-images/mine/1ahj) | NITRILE HYDRATASE | Descriptor: | FE (III) ION, NITRILE HYDRATASE (SUBUNIT ALPHA), NITRILE HYDRATASE (SUBUNIT BETA) | Authors: | Huang, W, Schneider, G, Lindqvist, Y. | Deposit date: | 1997-04-05 | Release date: | 1998-04-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of nitrile hydratase reveals a novel iron centre in a novel fold. Structure, 5, 1997
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2AHJ
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![BU of 2ahj by Molmil](/molmil-images/mine/2ahj) | NITRILE HYDRATASE COMPLEXED WITH NITRIC OXIDE | Descriptor: | 1,4-DIETHYLENE DIOXIDE, FE (III) ION, NITRIC OXIDE, ... | Authors: | Nagashima, S, Nakasako, M, Dohmae, N, Tsujimura, M, Takio, K, Odaka, M, Yohda, M, Kamiya, N, Endo, I. | Deposit date: | 1997-12-24 | Release date: | 1999-01-27 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Novel non-heme iron center of nitrile hydratase with a claw setting of oxygen atoms. Nat.Struct.Biol., 5, 1998
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2QDY
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![BU of 2qdy by Molmil](/molmil-images/mine/2qdy) | Crystal Structure of Fe-type NHase from Rhodococcus erythropolis AJ270 | Descriptor: | 2-METHYLPROPAN-1-AMINE, CHLORIDE ION, FE (III) ION, ... | Authors: | Song, L, Shi, J, Xue, Z, Wang, M.-X, Qian, S. | Deposit date: | 2007-06-22 | Release date: | 2008-05-13 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High resolution X-ray molecular structure of the nitrile hydratase from Rhodococcus erythropolis AJ270 reveals posttranslational oxidation of two cysteines into sulfinic acids and a novel biocatalytic nitrile hydration mechanism Biochem.Biophys.Res.Commun., 362, 2007
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7W8M
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![BU of 7w8m by Molmil](/molmil-images/mine/7w8m) | Crystal structure of Co-type nitrile hydratase mutant from Pseudomonas thermophila - A129R | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit beta, Nitrile hydratase | Authors: | Ma, D, Cheng, Z.Y, Hou, X.D, Peplowski, L, Lai, Q.P, Fu, K, Yin, D.J, Rao, Y.J, Zhou, Z.M. | Deposit date: | 2021-12-08 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis. Chem Sci, 13, 2022
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7W8L
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![BU of 7w8l by Molmil](/molmil-images/mine/7w8l) | Crystal Structure of Co-type nitrile hydratase mutant from Pseudonocardia thermophila - M46R | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit beta, Nitrile hydratase | Authors: | Ma, D, Cheng, Z.Y, Hou, X.D, Peplowski, L, Lai, Q.P, Fu, K, Yin, D.J, Rao, Y.J, Zhou, Z.M. | Deposit date: | 2021-12-08 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Insight into the broadened substrate scope of nitrile hydratase by static and dynamic structure analysis. Chem Sci, 13, 2022
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4ZGJ
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![BU of 4zgj by Molmil](/molmil-images/mine/4zgj) | Double Mutant H80A/H81A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-23 | Release date: | 2015-07-01 | Last modified: | 2015-07-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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4ZGD
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![BU of 4zgd by Molmil](/molmil-images/mine/4zgd) | Mutant R157A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-22 | Release date: | 2015-07-01 | Last modified: | 2015-07-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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4ZGE
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![BU of 4zge by Molmil](/molmil-images/mine/4zge) | Double Mutant H80W/H81W of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-22 | Release date: | 2015-07-01 | Last modified: | 2015-07-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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4OB0
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![BU of 4ob0 by Molmil](/molmil-images/mine/4ob0) | Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Phenyl Boronic Acid | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, ... | Authors: | Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L. | Deposit date: | 2014-01-06 | Release date: | 2014-11-26 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile. J.Am.Chem.Soc., 136, 2014
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1UGP
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![BU of 1ugp by Molmil](/molmil-images/mine/1ugp) | Crystal structure of Co-type nitrile hydratase complexed with n-butyric acid | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, ... | Authors: | Miyanaga, A, Fushinobu, S, Ito, K, Shoun, H, Wakagi, T. | Deposit date: | 2003-06-17 | Release date: | 2004-06-17 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding Eur.J.Biochem., 271, 2004
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1UGS
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![BU of 1ugs by Molmil](/molmil-images/mine/1ugs) | Crystal structure of aY114T mutant of Co-type nitrile hydratase | Descriptor: | COBALT (II) ION, Nitrile Hydratase alpha subunit, Nitrile Hydratase beta subunit | Authors: | Miyanaga, A, Fushinobu, S, Ito, K, Shoun, H, Wakagi, T. | Deposit date: | 2003-06-17 | Release date: | 2004-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding Eur.J.Biochem., 271, 2004
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4OB1
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![BU of 4ob1 by Molmil](/molmil-images/mine/4ob1) | Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Butaneboronic Acid via Co-crystallization | Descriptor: | 1-BUTANE BORONIC ACID, COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, ... | Authors: | Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L. | Deposit date: | 2014-01-06 | Release date: | 2014-11-26 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.631 Å) | Cite: | The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile. J.Am.Chem.Soc., 136, 2014
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1UGQ
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![BU of 1ugq by Molmil](/molmil-images/mine/1ugq) | Crystal structure of apoenzyme of Co-type nitrile hydratase | Descriptor: | Nitrile Hydratase alpha subunit, Nitrile Hydratase beta subunit | Authors: | Miyanaga, A, Fushinobu, S, Ito, K, Shoun, H, Wakagi, T. | Deposit date: | 2003-06-17 | Release date: | 2004-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding Eur.J.Biochem., 271, 2004
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1UGR
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![BU of 1ugr by Molmil](/molmil-images/mine/1ugr) | Crystal structure of aT109S mutant of Co-type nitrile hydratase | Descriptor: | COBALT (II) ION, Nitrile Hydratase alpha subunit, Nitrile Hydratase beta subunit | Authors: | Miyanaga, A, Fushinobu, S, Ito, K, Shoun, H, Wakagi, T. | Deposit date: | 2003-06-17 | Release date: | 2004-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding Eur.J.Biochem., 271, 2004
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4OB3
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![BU of 4ob3 by Molmil](/molmil-images/mine/4ob3) | Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila : A Reference Structure to Boronic Acid Inhibition of Nitrile Hydratase | Descriptor: | COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, ... | Authors: | Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L. | Deposit date: | 2014-01-06 | Release date: | 2014-11-26 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile. J.Am.Chem.Soc., 136, 2014
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4OB2
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![BU of 4ob2 by Molmil](/molmil-images/mine/4ob2) | Crystal Structure of Nitrile Hydratase from Pseudonocardia thermophila bound to Butaneboronic Acid via Crystal Soaking | Descriptor: | 1-BUTANE BORONIC ACID, COBALT (II) ION, Cobalt-containing nitrile hydratase subunit alpha, ... | Authors: | Rui, W, Salette, M, Ruslan, S, Richard, H, Dali, L. | Deposit date: | 2014-01-06 | Release date: | 2014-11-26 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile. J.Am.Chem.Soc., 136, 2014
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7QOP
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![BU of 7qop by Molmil](/molmil-images/mine/7qop) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | Descriptor: | CHLORIDE ION, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | Deposit date: | 2021-12-24 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase. Curr Res Struct Biol, 4, 2022
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7QOV
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![BU of 7qov by Molmil](/molmil-images/mine/7qov) | The wild type nitrile hydratase from Geobacillus pallidus | Descriptor: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase, ... | Authors: | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | Deposit date: | 2021-12-29 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase. Curr Res Struct Biol, 4, 2022
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7QOU
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![BU of 7qou by Molmil](/molmil-images/mine/7qou) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | Descriptor: | CHLORIDE ION, COBALT (II) ION, MAGNESIUM ION, ... | Authors: | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | Deposit date: | 2021-12-29 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Engineering enhanced thermostability into the Geobacillus pallidus nitrile hydratase. Curr Res Struct Biol, 4, 2022
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7QOY
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![BU of 7qoy by Molmil](/molmil-images/mine/7qoy) | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability | Descriptor: | CHLORIDE ION, COBALT (III) ION, Nitrile hydratase, ... | Authors: | Van Wyk, J.C, Cowan, D.A, Danson, M.J, Tsekoa, T.L, Sayed, M.F, Sewell, B.T. | Deposit date: | 2021-12-29 | Release date: | 2023-01-18 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A mutant of the nitrile hydratase from Geobacillus pallidus having enhanced thermostability To be published
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