7QI4
| Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2022-07-13 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk. Nat Commun, 15, 2024
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8OM4
| Small subunit of yeast mitochondrial ribosome. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.32 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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8CSS
| Human mitochondrial small subunit assembly intermediate (State D) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.36 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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7P2E
| Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Singh, V, Rorbach, J, Amunts, A. | Deposit date: | 2021-07-05 | Release date: | 2022-07-27 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules. Elife, 11, 2022
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8CSR
| Human mitochondrial small subunit assembly intermediate (State C) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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8CSQ
| Human mitochondrial small subunit assembly intermediate (State B) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.54 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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8OM2
| Small subunit of yeast mitochondrial ribosome in complex with METTL17/Rsm22. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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6ZM6
| Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Andrell, J, Amunts, A. | Deposit date: | 2020-07-01 | Release date: | 2021-01-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
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8D8L
| Yeast mitochondrial small subunit assembly intermediate (State 3) | Descriptor: | 15S ribosomal RNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Burnside, C, Harper, N, Klinge, S. | Deposit date: | 2022-06-08 | Release date: | 2022-12-14 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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7QI5
| Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2023-07-05 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk. Nat Commun, 15, 2024
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8CSP
| Human mitochondrial small subunit assembly intermediate (State A) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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7PNX
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and METTL15 conformation a | Descriptor: | 12S mitochondrial rRNA, 12S rRNA N4-methylcytidine (m4C) methyltransferase, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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8CST
| Human mitochondrial small subunit assembly intermediate (State E) | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Harper, N.J, Burnside, C, Klinge, S. | Deposit date: | 2022-05-13 | Release date: | 2022-12-14 | Last modified: | 2023-02-08 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Principles of mitoribosomal small subunit assembly in eukaryotes. Nature, 614, 2023
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6YW5
| The structure of the small subunit of the mitoribosome from Neurospora crassa | Descriptor: | 16S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Amunts, A, Itoh, Y, Naschberger, A. | Deposit date: | 2020-04-29 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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8ANY
| Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2022-08-06 | Release date: | 2023-08-16 | Last modified: | 2024-09-04 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome. Nat.Struct.Mol.Biol., 2024
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8OM3
| Small subunit of yeast mitochondrial ribosome in complex with IF3/Aim23. | Descriptor: | 15S mitochondrial rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | Authors: | Itoh, Y, Chicherin, I, Kamenski, P, Amunts, A. | Deposit date: | 2023-03-31 | Release date: | 2024-01-10 | Last modified: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | METTL17 is an Fe-S cluster checkpoint for mitochondrial translation. Mol.Cell, 84, 2024
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6ZM5
| Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | Descriptor: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | Authors: | Itoh, Y, Andrell, J, Amunts, A. | Deposit date: | 2020-07-01 | Release date: | 2021-01-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Mechanism of membrane-tethered mitochondrial protein synthesis. Science, 371, 2021
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7PO0
| Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in complex with RBFA and IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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8K2A
| Cryo-EM structure of the human 55S mitoribosome with Tigecycline | Descriptor: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2023-07-12 | Release date: | 2024-07-10 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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7PO3
| Human mitochondrial ribosome small subunit | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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7PO1
| Initiation complex of human mitochondrial ribosome small subunit with IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2021-09-08 | Release date: | 2022-06-15 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Mechanism of mitoribosomal small subunit biogenesis and preinitiation. Nature, 606, 2022
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6VMI
| Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-28 | Release date: | 2020-08-05 | Last modified: | 2021-02-17 | Method: | ELECTRON MICROSCOPY (2.96 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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6RW4
| Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3 | Descriptor: | 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ... | Authors: | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | Deposit date: | 2019-06-03 | Release date: | 2020-06-03 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Distinct pre-initiation steps in human mitochondrial translation. Nat Commun, 11, 2020
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6VLZ
| Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | Descriptor: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | Authors: | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | Deposit date: | 2020-01-27 | Release date: | 2020-08-05 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun, 11, 2020
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7QI6
| Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | Descriptor: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | Authors: | Singh, V, Itoh, Y, Amunts, A. | Deposit date: | 2021-12-14 | Release date: | 2023-05-17 | Last modified: | 2024-07-31 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk. Nat Commun, 15, 2024
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