3LUI
 
 | | Crystal structure of the SNX17 PX domain with bound sulphate | | Descriptor: | SULFATE ION, Sorting nexin-17 | | Authors: | Ghai, R, Collins, B.M. | | Deposit date: | 2010-02-17 | | Release date: | 2010-03-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases
Proc.Natl.Acad.Sci.USA, 2011
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7X4O
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1OCU
 | | Crystal structure of the yeast PX-domain protein Grd19p (sorting nexin 3) complexed to phosphatidylinosytol-3-phosphate. | | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, SORTING NEXIN | | Authors: | Zhou, C.Z, Li de La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, de la Torre, F, Poupon, A, Janin, J, van Tilbeurgh, H. | | Deposit date: | 2003-02-10 | | Release date: | 2003-12-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate.
J. Biol. Chem., 278, 2003
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3P0C
 | | Nischarin PX-domain | | Descriptor: | GLYCEROL, Nischarin | | Authors: | Schutz, P, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Kol, S, Kotenyova, T, Kouznetsova, E, Moche, M, Nyman, T, Persson, C, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Wahlberg, E, Welin, M, Weigelt, J, Nordlund, P, Schuler, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2010-09-28 | | Release date: | 2010-10-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.273 Å) | | Cite: | Crystal structure of Nischarin PX-domain
to be published
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2YPS
 | | Crystal structure of the PX domain of human sorting nexin 3 | | Descriptor: | SORTING NEXIN-3 | | Authors: | Canning, P, Kiyani, W, Froese, D.S, Krojer, T, Strain-Damerell, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Yue, W.W. | | Deposit date: | 2012-10-31 | | Release date: | 2013-03-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the Px Domain of Human Sorting Nexin 3
To be Published
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8HQL
 | | Crystal structure of mouse SNX25 PX domain | | Descriptor: | ACETIC ACID, CHLORIDE ION, GLYCEROL, ... | | Authors: | Yu, Z, Xu, J, Liu, J. | | Deposit date: | 2022-12-13 | | Release date: | 2023-12-20 | | Last modified: | 2024-08-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Redox-modulated SNX25 as a novel regulator of GPCR-G protein signaling from endosomes.
Redox Biol, 75, 2024
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8ESF
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4ON3
 | | Crystal structure of human sorting nexin 10 (SNX10) | | Descriptor: | NITRATE ION, PENTAETHYLENE GLYCOL, SODIUM ION, ... | | Authors: | Xu, T, Xu, J, Wang, Q, Liu, J. | | Deposit date: | 2014-01-28 | | Release date: | 2014-09-24 | | Last modified: | 2014-12-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis.
Proteins, 82, 2014
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4P2I
 | | Crystal structure of the mouse SNX19 PX domain | | Descriptor: | MKIAA0254 protein | | Authors: | Collins, B.M. | | Deposit date: | 2014-03-04 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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4P2J
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2IWL
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2I4K
 | | Solution Structure of the PX domain of Sorting Nexin 1 | | Descriptor: | Sorting nexin-1 | | Authors: | Watson, M.J, Zhong, Q, Lazar, C.S, Hounslow, A.M, Gill, G.N, Waltho, J.P. | | Deposit date: | 2006-08-22 | | Release date: | 2006-10-03 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Determinants of the Endosomal Localization of Sorting Nexin 1
Mol.Cell.Biol., 16, 2005
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1GD5
 | | SOLUTION STRUCTURE OF THE PX DOMAIN FROM HUMAN P47PHOX NADPH OXIDASE | | Descriptor: | NEUTROPHIL CYTOSOL FACTOR 1 | | Authors: | Hiroaki, H, Ago, T, Ito, T, Sumimoto, H, Kohda, D. | | Deposit date: | 2000-09-14 | | Release date: | 2001-06-13 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the PX domain, a target of the SH3 domain.
Nat.Struct.Biol., 8, 2001
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1H6H
 | | Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate | | Descriptor: | 2-(BUTANOYLOXY)-1-{[(HYDROXY{[2,3,4,6-TETRAHYDROXY-5-(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]METHYL}ETHYL BUTANOATE, GLYCEROL, NEUTROPHIL CYTOSOL FACTOR 4 | | Authors: | Karathanassis, D, Bravo, J, Pacold, M, Perisic, O, Williams, R.L. | | Deposit date: | 2001-06-15 | | Release date: | 2001-11-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Crystal Structure of the Px Domain from P40Phox Bound to Phosphatidylinositol 3-Phosphate
Mol.Cell, 8, 2001
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1O7K
 | | human p47 PX domain complex with sulphates | | Descriptor: | NEUTROPHIL CYTOSOL FACTOR 1, SULFATE ION | | Authors: | Karathanassis, D, Bravo, J, Perisic, O, Pacold, C.M, Williams, R.L. | | Deposit date: | 2002-11-07 | | Release date: | 2002-11-20 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Binding of the Px Domain of P47Phox to Phosphatidylinositol 3.4-Bisphosphate and Phosphatidic Acid is Masked by an Intramolecular Interaction
Embo J., 21, 2002
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1OCS
 | | Crystal structure of the yeast PX-doamin protein Grd19p (sorting nexin3) complexed to phosphatidylinosytol-3-phosphate. | | Descriptor: | GLYCEROL, SORTING NEXIN GRD19 | | Authors: | Zhou, C.Z, Li De La Sierra-Gallay, I, Cheruel, S, Collinet, B, Minard, P, Blondeau, K, Henkes, G, Aufrere, R, Leulliot, N, Graille, M, Sorel, I, Savarin, P, De La Torre, F, Poupon, A, Janin, J, Van Tilbeurgh, H. | | Deposit date: | 2003-02-10 | | Release date: | 2003-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal Structure of the Yeast Phox Homology (Px) Protein Grd19P (Sorting Nexin 3) Complexed to Phosphatidylinositol-3-Phosphate
J.Biol.Chem., 278, 2003
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1KMD
 | | SOLUTION STRUCTURE OF THE VAM7P PX DOMAIN | | Descriptor: | Vacuolar morphogenesis protein VAM7 | | Authors: | Lu, J, Garcia, J, Dulubova, I, Sudhof, T.C, Rizo, J. | | Deposit date: | 2001-12-14 | | Release date: | 2002-06-12 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the Vam7p PX domain.
Biochemistry, 41, 2002
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1KQ6
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5ZN9
 | | Crystal structure of PX domain | | Descriptor: | SULFATE ION, Sorting nexin-27 | | Authors: | Li, Y, Zhu, Z, Li, F, Liao, S, Xu, C. | | Deposit date: | 2018-04-08 | | Release date: | 2019-04-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.776 Å) | | Cite: | Crystal structure of PX domain
To Be Published
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6BUB
 | | Crystal structure of the PI3KC2alpha PX domain in space group P432 | | Descriptor: | GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION | | Authors: | Chen, K.-E, Collins, B.M. | | Deposit date: | 2017-12-09 | | Release date: | 2018-10-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
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2REA
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4PQP
 | | Crystal structure of human SNX14 PX domain in space group P43212 | | Descriptor: | GLYCEROL, Sorting nexin-14 | | Authors: | Mas, C, Norwood, S, Bugarcic, A, Kinna, G, Leneva, N, Kovtun, O, Teasdale, R, Collins, B. | | Deposit date: | 2014-03-03 | | Release date: | 2014-09-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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3HPB
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6N5X
 | | Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | | Descriptor: | GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500), Sorting nexin-5,Cation-independent mannose-6-phosphate receptor | | Authors: | Collins, B, Paul, B, Weeratunga, S. | | Deposit date: | 2018-11-22 | | Release date: | 2019-09-18 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.051 Å) | | Cite: | Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
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2RED
 | | Crystal structures of C2ALPHA-PI3 kinase PX-domain domain indicate conformational change associated with ligand binding. | | Descriptor: | GLYCEROL, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide | | Authors: | Parkinson, G.N, Vines, D, Driscoll, P.C, Djordjevic, S. | | Deposit date: | 2007-09-26 | | Release date: | 2007-11-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of PI3K-C2alpha PX domain indicate conformational change associated with ligand binding
Bmc Struct.Biol., 8, 2008
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