PDB: 665 resultsInfo pagesStatus searchChemie searchBIRD

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9IMP	The complex of PDZ3 and PBM Descriptor: INSC spindle orientation adaptor protein, Partitioning defective 3 homolog Authors: Huang, S.J. Deposit date: 2024-07-04 Release date: 2024-09-11 Last modified: 2024-09-18 Method: X-RAY DIFFRACTION (2.87 Å) Cite: mInsc coordinates Par3 and NuMA condensates for assembly of the spindle orientation machinery in asymmetric cell division. Int.J.Biol.Macromol., 279, 2024
5WOU	Crystal Structure of drosophila melanogaster Scribble PDZ1 domain in complex with Guk-Holder Descriptor: 1,2-ETHANEDIOL, GUK-holder, isoform A, ... Authors: Caria, S, Kvansakul, M. Deposit date: 2017-08-03 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Drosophila melanogasterGuk-holder interacts with the Scribbled PDZ1 domain and regulates epithelial development with Scribbled and Discs Large. J. Biol. Chem., 293, 2018
8CQY	Crystal structure of the PTPN3 PDZ domain bound to the PBM TACE C-terminal peptide Descriptor: Disintegrin and metalloproteinase domain-containing protein 17, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 Authors: Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. Deposit date: 2023-03-07 Release date: 2023-05-10 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
6OV7	CFTR Associated Ligand (CAL) PDZ domain bound to peptide kCAL01 Descriptor: Golgi-associated PDZ and coiled-coil motif-containing protein, kCAL01 peptide Authors: Gill, N.P, Madden, D.R. Deposit date: 2019-05-07 Release date: 2019-11-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand. J.Phys.Chem.B, 123, 2019
1W9Q	Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide Descriptor: BENZOIC ACID, SYNTENIN 1, TNEFAF PEPTIDE Authors: Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, Z.S. Deposit date: 2004-10-15 Release date: 2006-03-22 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry, 45, 2006
1VJ6	PDZ2 from PTP-BL in complex with the C-terminal ligand from the APC protein Descriptor: Adenomatous polyposis coli protein, protein-tyrosine-phosphatase (nonreceptor type 13) Authors: Walma, T, Vuister, G.W. Deposit date: 2004-02-03 Release date: 2005-11-01 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering. Structure, 14, 2006
2FCF	The crystal structure of the 7th PDZ domain of MPDZ (MUPP-1) Descriptor: Multiple PDZ domain protein Authors: Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) Deposit date: 2005-12-12 Release date: 2006-01-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16, 2007
4WYT	Crystal Structure of Scribble PDZ34 tandem at 2.6 Angstroms Descriptor: CHLORIDE ION, Protein scribble homolog Authors: Ren, J.Q, Feng, W. Deposit date: 2014-11-18 Release date: 2015-10-21 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule. Biochem.J., 468, 2015
2FNE	The crystal structure of the 13th PDZ domain of MPDZ Descriptor: Multiple PDZ domain protein Authors: Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) Deposit date: 2006-01-11 Release date: 2006-01-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions. Protein Sci., 16, 2007
3KZD	Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Descriptor: T-lymphoma invasion and metastasis-inducing protein 1 Authors: Shepherd, T.R, Fuentes, E.J. Deposit date: 2009-12-08 Release date: 2010-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion. J.Mol.Biol., 398, 2010
8OEP	Crystal structure of the PTPN3 PDZ domain bound to the HPV18 E6 oncoprotein C-terminal peptide Descriptor: Protein E6, SODIUM ION, Tyrosine-protein phosphatase non-receptor type 3 Authors: Genera, M, Colcombet-Cazenave, B, Croitoru, A, Raynal, B, Mechaly, A, Caillet, J, Haouz, A, Wolff, N, Caillet-Saguy, C. Deposit date: 2023-03-11 Release date: 2023-05-10 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Interactions of the protein tyrosine phosphatase PTPN3 with viral and cellular partners through its PDZ domain: insights into structural determinants and phosphatase activity. Front Mol Biosci, 10, 2023
3KZE	Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in Complex With SSRKEYYA Peptide Descriptor: Synthetic Peptide, T-lymphoma invasion and metastasis-inducing protein 1 Authors: Shepherd, T.R, Fuentes, E.J. Deposit date: 2009-12-08 Release date: 2010-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion. J.Mol.Biol., 398, 2010
6LCB	Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 Descriptor: 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 Authors: Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. Deposit date: 2019-11-18 Release date: 2020-11-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 To Be Published
6KZ1	Complex structure of Whirlin and Myosin XVa Descriptor: Myosin XVa, Whirlin Authors: Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. Deposit date: 2019-09-22 Release date: 2020-09-23 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.694 Å) Cite: Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
5IC3	CAL PDZ domain with peptide and inhibitor Descriptor: 4-[methyl(nitroso)amino]benzene-1,2-diol, Golgi-associated PDZ and coiled-coil motif-containing protein, HPV18E6 Peptide Authors: Zhao, Y, Madden, D.R. Deposit date: 2016-02-22 Release date: 2017-08-09 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: CAL PDZ domain with peptide and inhibitor To Be Published
4E35	Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL50 peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2012-03-09 Release date: 2012-12-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
4UU5	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE Descriptor: 2,2,4,4,6,6,8-heptamethylnonane, CHLORIDE ION, MAGUK P55 SUBFAMILY MEMBER 5, ... Authors: Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. Deposit date: 2014-07-24 Release date: 2015-01-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.23 Å) Cite: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4E34	Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ... Authors: Amacher, J.F, Beck, T, Madden, D.R. Deposit date: 2012-03-09 Release date: 2012-12-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.395 Å) Cite: Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
1MFG	The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor Descriptor: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment Authors: Birrane, G, Chung, J, Ladias, J.A. Deposit date: 2002-08-10 Release date: 2003-01-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Novel mode of ligand recognition by the erbin PDZ domain J.Biol.Chem., 278, 2003
1MFL	The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor Descriptor: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment. Authors: Birrane, G, Chung, J, Ladias, J.A. Deposit date: 2002-08-12 Release date: 2003-01-21 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Novel mode of ligand recognition by the erbin PDZ domain J.Biol.Chem., 278, 2003
4E3B	Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide Descriptor: Tax1-binding protein 3, iCAL50 peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2012-03-09 Release date: 2012-12-26 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
7RM8	Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion Authors: Healy, M.D, Collins, B.M, Mobli, M. Deposit date: 2021-07-26 Release date: 2022-08-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30, 2022
6UBH	Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide Descriptor: Erbin, SODIUM ION, peptide Authors: Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S. Deposit date: 2019-09-11 Release date: 2020-07-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain. J.Mol.Biol., 433, 2021
4UU6	CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Ivanova, M.E, Purkiss, A.G, McDonald, N.Q. Deposit date: 2014-07-24 Release date: 2015-01-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr. D Biol. Crystallogr., 71, 2015
1MC7	Solution Structure of mDvl1 PDZ domain Descriptor: Segment polarity protein dishevelled homolog DVL-1 Authors: Wong, H.-C, Bourdelas, A, Shao, Y, Wu, D, Shi, D.L, Zheng, J. Deposit date: 2002-08-05 Release date: 2003-09-23 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled Mol.Cell, 12, 2003

 

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