4JON
 
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4H87
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8WWY
 | | Crystal structure of mouse TIFA/TIFAB heterodimer | | Descriptor: | (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B | | Authors: | Nakamura, T. | | Deposit date: | 2023-10-27 | | Release date: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Proc.Natl.Acad.Sci.USA, 121, 2024
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1DMZ
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6C4U
 | | Engineered FHA with Myc-pTBD peptide | | Descriptor: | Forkhead-associated 1, GLYCEROL, Myc-pTBD peptide | | Authors: | Kall, S.L, Lavie, A. | | Deposit date: | 2018-01-12 | | Release date: | 2018-05-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc.
N Biotechnol, 45, 2018
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7RJ3
 | | Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis | | Descriptor: | DI(HYDROXYETHYL)ETHER, Glycogen accumulation regulator GarA | | Authors: | Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2021-07-20 | | Release date: | 2021-07-28 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal Structure of the Forkhead Associated (FHA) Domain of the Glycogen Accumulation Regulator (GarA) from Mycobacterium tuberculosis.
To Be Published
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2PIE
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4QCJ
 | | Crystal Structure of OdhI from Corynebacterium glutamicum | | Descriptor: | Oxoglutarate dehydrogenase inhibitor | | Authors: | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | | Deposit date: | 2014-05-12 | | Release date: | 2014-07-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model.
J.Biotechnol., 191, 2014
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1QU5
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1UHT
 | | Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein | | Descriptor: | expressed protein | | Authors: | Tomizawa, T, Inoue, M, Koshiba, S, Hayashi, F, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Matsuda, T, Seki, E, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Shinozaki, K, Seki, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-07-10 | | Release date: | 2004-01-10 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of The FHA Domain of Arabidopsis thaliana Hypothetical Protein
To be Published
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1R21
 | | Solution Structure of human Ki67 FHA Domain | | Descriptor: | Antigen Ki-67 | | Authors: | Byeon, I.J, Li, H, Tsai, M.D. | | Deposit date: | 2003-09-25 | | Release date: | 2003-12-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of Human Ki67 FHA Domain and its Binding to a Phosphoprotein Fragment from hNIFK Reveal Unique Recognition Sites and New Views to the Structural Basis of FHA Domain Functions
J.Mol.Biol., 335, 2004
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1WLN
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5T2F
 | | Structure of the FHA1 domain of Rad53 bound to the BRCT domain of Dbf4 | | Descriptor: | 1,2-ETHANEDIOL, DDK kinase regulatory subunit DBF4,Serine/threonine-protein kinase RAD53 chimeric protein | | Authors: | Guarne, A, Almawi, A.W, Matthews, L.A. | | Deposit date: | 2016-08-23 | | Release date: | 2017-03-15 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.66 Å) | | Cite: | 'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.
Sci Rep, 6, 2016
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5T2S
 | | Structure of the FHA1 domain of Rad53 bound simultaneously to the BRCT domain of Dbf4 and a phosphopeptide. | | Descriptor: | ASP-GLY-GLU-SER-TPO-ASP-GLU-ASP-ASP, DDK kinase regulatory subunit DBF4,Serine/threonine-protein kinase RAD53, GLYCEROL | | Authors: | Guarne, A, Almawi, A, Matthews, L. | | Deposit date: | 2016-08-24 | | Release date: | 2016-10-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | 'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.
Sci Rep, 6, 2016
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6CCD
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3ELS
 | | Crystal Structure of Yeast Pml1p, Residues 51-204 | | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Trowitzsch, S, Weber, G, Luehrmann, R, Wahl, M.C. | | Deposit date: | 2008-09-23 | | Release date: | 2009-02-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
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3ELV
 | | Crystal Structure of Full-Length Yeast Pml1p | | Descriptor: | Pre-mRNA leakage protein 1, SULFATE ION | | Authors: | Trowitzsch, S, Weber, G, L hrmann, R, Wahl, M.C. | | Deposit date: | 2008-09-23 | | Release date: | 2009-02-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex.
J.Mol.Biol., 385, 2009
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2A0T
 | | NMR structure of the FHA1 domain of Rad53 in complex with a biological relevant phosphopeptide derived from Madt1 | | Descriptor: | Hypothetical 73.8 kDa protein in SAS3-SEC17 intergenic region, residues 301-310, Serine/threonine-protein kinase RAD53 | | Authors: | Mahajan, A, Yuan, C, Pike, B.L, Heierhorst, J, Chang, C.-F, Tsai, M.-D. | | Deposit date: | 2005-06-16 | | Release date: | 2005-11-08 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches
J.Am.Chem.Soc., 127, 2005
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1MZK
 | | NMR structure of kinase-interacting FHA domain of kinase associated protein phosphatase, KAPP in Arabidopsis | | Descriptor: | KINASE ASSOCIATED PROTEIN PHOSPHATASE | | Authors: | Lee, G, Ding, Z, Walker, J.C, Van Doren, S.R. | | Deposit date: | 2002-10-08 | | Release date: | 2003-09-09 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the forkhead-associated domain from the Arabidopsis receptor kinase-associated protein phosphatase.
Proc.Natl.Acad.Sci.USA, 100, 2003
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4ZGI
 | | Structure of Truncated Human TIFA | | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | | Authors: | Weng, J.H, Wei, T.Y.W, Hsieh, Y.C, Huang, C.C.F, Wu, P.Y.G, Chen, E.S.W, Huang, K.F, Chen, C.J, Tsai, M.D. | | Deposit date: | 2015-04-23 | | Release date: | 2015-10-14 | | Last modified: | 2015-10-28 | | Method: | X-RAY DIFFRACTION (2.701 Å) | | Cite: | Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.
Biochemistry, 54, 2015
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6L9W
 | | Crystal structure of mouse TIFA (T9E/C36S mutant) | | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | | Authors: | Nakamura, T, Yamagata, Y. | | Deposit date: | 2019-11-11 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
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1LGP
 | | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein complexed with tungstate | | Descriptor: | TUNGSTATE(VI)ION, cell cycle checkpoint protein CHFR | | Authors: | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | | Deposit date: | 2002-04-16 | | Release date: | 2002-05-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
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6L9V
 | | Crystal structure of mouse TIFA (T9D/C36S mutant) | | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | | Authors: | Nakamura, T, Yamagata, Y. | | Deposit date: | 2019-11-11 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
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1LGQ
 | | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein | | Descriptor: | cell cycle checkpoint protein CHFR | | Authors: | Stavridi, E.S, Huyen, Y, Loreto, I.R, Scolnick, D.M, Halazonetis, T.D, Pavletich, N.P, Jeffrey, P.D. | | Deposit date: | 2002-04-16 | | Release date: | 2002-05-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
Structure, 10, 2002
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6L9U
 | | Crystal structure of mouse TIFA | | Descriptor: | TRAF-interacting protein with FHA domain-containing protein A | | Authors: | Nakamura, T, Yamagata, Y. | | Deposit date: | 2019-11-11 | | Release date: | 2020-04-01 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
Sci Rep, 10, 2020
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