3EKS
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![BU of 3eks by Molmil](/molmil-images/mine/3eks) | Crystal Structure of Monomeric Actin bound to Cytochalasin D | Descriptor: | (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylidene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, ... | Authors: | Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M. | Deposit date: | 2008-09-19 | Release date: | 2008-10-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of monomeric actin bound to cytochalasin D. J.Mol.Biol., 384, 2008
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4CJ7
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![BU of 4cj7 by Molmil](/molmil-images/mine/4cj7) | Structure of Crenactin, an archeal actin-like protein | Descriptor: | ACTIN/ACTIN FAMILY PROTEIN, ADENOSINE-5'-DIPHOSPHATE | Authors: | Izore, T, Duman, R.E, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2013-12-19 | Release date: | 2014-01-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crenactin from Pyrobaculum Calidifontis is Closely Related to Actin in Structure and Forms Steep Helical Filaments. FEBS Lett., 588, 2014
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2OAN
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![BU of 2oan by Molmil](/molmil-images/mine/2oan) | Structure of oxidized beta-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Schmitzberger, F, Lassing, I, Nordlund, P, Lindberg, U. | Deposit date: | 2006-12-16 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.606 Å) | Cite: | Molecular and Structural Basis for Redox Regulation of beta-Actin. J.Mol.Biol., 370, 2007
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3QB0
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![BU of 3qb0 by Molmil](/molmil-images/mine/3qb0) | Crystal structure of Actin-related protein Arp4 from S. cerevisiae complexed with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 4, CALCIUM ION | Authors: | Fenn, S, Breitsprecher, D, Gerhold, C.B, Witte, G, Faix, J, Hopfner, K.P. | Deposit date: | 2011-01-12 | Release date: | 2011-05-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.404 Å) | Cite: | Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin. Embo J., 30, 2011
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6QRI
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![BU of 6qri by Molmil](/molmil-images/mine/6qri) | Structure of rabbit G-actin in complex with chivosazole A | Descriptor: | (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Schneider, S, Wang, S, Zahler, S. | Deposit date: | 2019-02-19 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Chivosazole A Modulates Protein-Protein Interactions of Actin. J.Nat.Prod., 82, 2019
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2VYP
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![BU of 2vyp by Molmil](/molmil-images/mine/2vyp) | Rabbit-muscle G-actin in complex with myxobacterial rhizopodin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Hagelueken, G, Albrecht, S.C, Steinmetz, H, Jansen, R, Heinz, D.W, Kalesse, M, Schubert, W.-D. | Deposit date: | 2008-07-25 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Absolute Configuration of Rhizopodin and its Inhibition of Actin Polymerization by Dimerization. Angew.Chem.Int.Ed.Engl., 48, 2009
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1WUA
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![BU of 1wua by Molmil](/molmil-images/mine/1wua) | The structure of Aplyronine A-actin complex | Descriptor: | (8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(MET HYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTE TRACOSA-3,5,15,21-TETRAEN-8-YL N,N,O-TRIMETHYLSERINATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Hirata, K, Muraoka, S, Suenaga, K, Kuroda, T, Kato, K, Tanaka, H, Yamamoto, M, Takata, M, Yamada, K, Kigoshi, H. | Deposit date: | 2004-12-03 | Release date: | 2006-02-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure basis for antitumor effect of aplyronine a J.Mol.Biol., 356, 2006
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6T24
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![BU of 6t24 by Molmil](/molmil-images/mine/6t24) | Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Pospich, S, Merino, F, Raunser, S. | Deposit date: | 2019-10-07 | Release date: | 2020-03-04 | Last modified: | 2020-04-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure, 28, 2020
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9C4B
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![BU of 9c4b by Molmil](/molmil-images/mine/9c4b) | Second BAF53a of the human TIP60 complex | Descriptor: | Actin-like protein 6A | Authors: | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | Deposit date: | 2024-06-03 | Release date: | 2024-08-14 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex. Science, 385, 2024
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3G37
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![BU of 3g37 by Molmil](/molmil-images/mine/3g37) | Cryo-EM structure of actin filament in the presence of phosphate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Wakabayshi, T, Murakami, K, Yasunaga, T, Noguchi, T.Q, Uyeda, T.Q. | Deposit date: | 2009-02-02 | Release date: | 2010-11-03 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structural basis for actin assembly, activation of ATP hydrolysis, and delayed phosphate release Cell(Cambridge,Mass.), 143, 2010
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3HBT
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![BU of 3hbt by Molmil](/molmil-images/mine/3hbt) | The structure of native G-actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, CALCIUM ION, ... | Authors: | Wang, H, Robinson, R.C, Burtnick, L.D. | Deposit date: | 2009-05-05 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structure of native G-actin Cytoskeleton (Hoboken), 67, 2010
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1IJJ
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![BU of 1ijj by Molmil](/molmil-images/mine/1ijj) | THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Vorobiev, S.M, Bubb, M.R, Almo, S.C. | Deposit date: | 2001-04-26 | Release date: | 2002-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution J.Biol.Chem., 277, 2002
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1J6Z
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![BU of 1j6z by Molmil](/molmil-images/mine/1j6z) | UNCOMPLEXED ACTIN | Descriptor: | ACTIN ALPHA 1, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Otterbein, L.R, Graceffa, P, Dominguez, R. | Deposit date: | 2001-05-15 | Release date: | 2001-08-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The crystal structure of uncomplexed actin in the ADP state. Science, 293, 2001
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5JLF
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![BU of 5jlf by Molmil](/molmil-images/mine/5jlf) | |
6DJO
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![BU of 6djo by Molmil](/molmil-images/mine/6djo) | Cryo-EM structure of ADP-actin filaments | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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6DJM
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![BU of 6djm by Molmil](/molmil-images/mine/6djm) | Cryo-EM structure of AMPPNP-actin filaments | Descriptor: | Actin, alpha skeletal muscle, MAGNESIUM ION, ... | Authors: | Chou, S.Z, Pollard, T.D. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
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6WVT
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![BU of 6wvt by Molmil](/molmil-images/mine/6wvt) | Structural basis of alphaE-catenin - F-actin catch bond behavior | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Xu, X.P, Pokutta, S, Torres, M, Swift, M.F, Hanein, D, Volkmann, N, Weis, W.I. | Deposit date: | 2020-05-06 | Release date: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Structural basis of alpha E-catenin-F-actin catch bond behavior. Elife, 9, 2020
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4WYB
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![BU of 4wyb by Molmil](/molmil-images/mine/4wyb) | Structure of the Bud6 flank domain in complex with actin | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Eck, M.J, Park, E, Zheng, W. | Deposit date: | 2014-11-17 | Release date: | 2015-08-19 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.493 Å) | Cite: | Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif. Structure, 23, 2015
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2Y83
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![BU of 2y83 by Molmil](/molmil-images/mine/2y83) | Actin filament pointed end | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Narita, A, Oda, T, Maeda, Y. | Deposit date: | 2011-02-02 | Release date: | 2011-03-30 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (22.9 Å) | Cite: | Structural Basis for the Slow Dynamics of the Actin Filament Pointed End. Embo J., 30, 2011
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4K41
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![BU of 4k41 by Molmil](/molmil-images/mine/4k41) | Crystal structure of actin in complex with marine macrolide kabiramide C | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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4K42
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![BU of 4k42 by Molmil](/molmil-images/mine/4k42) | Crystal structure of actin in complex with synthetic AplC tail analogue SF01 [(3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate] | Descriptor: | (3R,4S,5R,6S,10R,11R,12R)-11-(acetyloxy)-1-(benzyloxy)-14-[formyl(methyl)amino]-5-hydroxy-4,6,10,12-tetramethyl-9-oxotetradecan-3-yl propanoate, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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2ZWH
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![BU of 2zwh by Molmil](/molmil-images/mine/2zwh) | Model for the F-actin structure | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Oda, T, Iwasa, M, Aihara, T, Maeda, Y, Narita, A. | Deposit date: | 2008-12-05 | Release date: | 2009-01-20 | Last modified: | 2017-10-11 | Method: | FIBER DIFFRACTION (3.3 Å) | Cite: | The nature of the globular- to fibrous-actin transition. Nature, 457, 2009
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4K43
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![BU of 4k43 by Molmil](/molmil-images/mine/4k43) | Crystal structure of actin in complex with synthetic AplC tail analogue GC04 [N-{(1E,4R,5R,7E,9S,10S,11S)-4,10-dimethoxy-11-[(2S,4S,5S)-2-(4-methoxyphenyl)-5-methyl-1,3-dioxan-4-yl]-5,9-dimethyl-6-oxododeca-1,7-dien-1-yl}-N-methylformamide] | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Pereira, J.H, Petchprayoon, C, Moriarty, N.W, Fink, S.J, Cecere, G, Paterson, I, Adams, P.D, Marriott, G. | Deposit date: | 2013-04-11 | Release date: | 2014-10-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural and biochemical studies of actin in complex with synthetic macrolide tail analogues. Chemmedchem, 9, 2014
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4M63
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![BU of 4m63 by Molmil](/molmil-images/mine/4m63) | Crystal Structure of a Filament-Like Actin Trimer Bound to the Bacterial Effector VopL | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION, ... | Authors: | Tomchick, D.R, Zahm, J.A, Rosen, M.K. | Deposit date: | 2013-08-08 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.748 Å) | Cite: | The Bacterial Effector VopL Organizes Actin into Filament-like Structures. Cell(Cambridge,Mass.), 155, 2013
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6T20
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![BU of 6t20 by Molmil](/molmil-images/mine/6t20) | Cryo-EM structure of phalloidin-stabilized F-actin (aged) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Pospich, S, Merino, F, Raunser, S. | Deposit date: | 2019-10-07 | Release date: | 2020-03-04 | Last modified: | 2020-04-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure, 28, 2020
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