3KSA
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![BU of 3ksa by Molmil](/molmil-images/mine/3ksa) | Detailed structural insight into the DNA cleavage complex of type IIA topoisomerases (cleaved form) | Descriptor: | 5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3', 5'-D(*CP*TP*GP*TP*TP*TP*TP*A*CP*GP*TP*GP*CP*AP*T)-3', 5'-D(P*AP*GP*TP*CP*AP*TP*TP*CP*AP*TP*GP*AP*CP*CP*TP*TP*GP*GP*T)-3', ... | Authors: | Laponogov, I, Pan, X.-S, Veselkov, D.A, McAuley, K.E, Fisher, L.M, Sanderson, M.R. | Deposit date: | 2009-11-21 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Plos One, 5, 2010
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7NG9
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![BU of 7ng9 by Molmil](/molmil-images/mine/7ng9) | |
5GVB
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![BU of 5gvb by Molmil](/molmil-images/mine/5gvb) | SepB domain of human AND-1 | Descriptor: | WD repeat and HMG-box DNA-binding protein 1 | Authors: | Guan, C.C, Li, J. | Deposit date: | 2016-09-05 | Release date: | 2017-04-19 | Last modified: | 2017-06-21 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structure and polymerase-recognition mechanism of the crucial adaptor protein AND-1 in the human replisome. J. Biol. Chem., 292, 2017
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3KWM
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![BU of 3kwm by Molmil](/molmil-images/mine/3kwm) | Crystal structure of ribose-5-isomerase A | Descriptor: | D-Glyceraldehyde, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | Authors: | Orlikowska, M, Rostankowski, R, Nakka, C, Hattne, J, Grimshaw, S, Borek, D, Otwinowski, Z, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-12-01 | Release date: | 2010-01-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: |
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5GJE
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![BU of 5gje by Molmil](/molmil-images/mine/5gje) | Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J. | Deposit date: | 2016-06-29 | Release date: | 2017-01-18 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (21 Å) | Cite: | Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1 Cell Rep, 18, 2017
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5GVL
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![BU of 5gvl by Molmil](/molmil-images/mine/5gvl) | Plasmodium vivax SHMT bound with PLP-glycine and GS182 | Descriptor: | (4~{S})-6-azanyl-4-[3-cyano-5-[5-(methoxymethyl)thiophen-2-yl]phenyl]-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazole-5-carbonitrile, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | Authors: | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G. | Deposit date: | 2016-09-06 | Release date: | 2017-07-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures J. Med. Chem., 60, 2017
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5GK7
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![BU of 5gk7 by Molmil](/molmil-images/mine/5gk7) | Structure of E.Coli fructose 1,6-bisphosphate aldolase bound to Tris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Fructose-bisphosphate aldolase class 2, ... | Authors: | Tran, T.H, Huynh, K.H, Ho, T.H, Kang, L.W. | Deposit date: | 2016-07-03 | Release date: | 2017-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of E.Coli fructose 1,6-bisphosphate aldolase, Tris bound form To Be Published
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3KX8
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![BU of 3kx8 by Molmil](/molmil-images/mine/3kx8) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK | Descriptor: | fluoroacetyl-CoA thioesterase | Authors: | Chirgadze, D.Y, Dias, M.V.B, Huang, F, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | Deposit date: | 2009-12-02 | Release date: | 2010-04-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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5GW4
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![BU of 5gw4 by Molmil](/molmil-images/mine/5gw4) | Structure of Yeast NPP-TRiC | Descriptor: | T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ... | Authors: | Zang, Y, Jin, M, Wang, H, Cong, Y. | Deposit date: | 2016-09-08 | Release date: | 2016-10-26 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM. Nat. Struct. Mol. Biol., 23, 2016
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3KTT
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![BU of 3ktt by Molmil](/molmil-images/mine/3ktt) | Atomic model of bovine TRiC CCT2(beta) subunit derived from a 4.0 Angstrom cryo-EM map | Descriptor: | T-complex protein 1 subunit beta | Authors: | Cong, Y, Baker, M.L, Ludtke, S.J, Frydman, J, Chiu, W. | Deposit date: | 2009-11-25 | Release date: | 2010-03-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc.Natl.Acad.Sci.USA, 107, 2010
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5GKE
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![BU of 5gke by Molmil](/molmil-images/mine/5gke) | Structure of EndoMS-dsDNA1 complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*CP*GP*CP*TP*AP*CP*AP*TP*GP*TP*CP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*GP*AP*CP*GP*TP*GP*TP*AP*GP*CP*G)-3'), ... | Authors: | Nakae, S, Hijikata, A, Tsuji, T, Yonezawa, K, Kouyama, K, Mayanagi, K, Ishino, S, Ishino, Y, Shirai, T. | Deposit date: | 2016-07-04 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the EndoMS-DNA Complex as Mismatch Restriction Endonuclease Structure, 24, 2016
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3KXR
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![BU of 3kxr by Molmil](/molmil-images/mine/3kxr) | Structure of the cystathionine beta-synthase pair domain of the putative Mg2+ transporter SO5017 from Shewanella oneidensis MR-1. | Descriptor: | CHLORIDE ION, Magnesium transporter, putative | Authors: | Fratczak, Z, Zimmerman, M.D, Chruszcz, M, Cymborowski, M, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-12-03 | Release date: | 2009-12-15 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structure of the cystathionine beta-synthase pair domain of the putative Mg2+ transporter SO5017 from Shewanella oneidensis MR-1. To be Published
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5GZD
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![BU of 5gzd by Molmil](/molmil-images/mine/5gzd) | Galectin-8 N-terminal domain carbohydrate recognition domain | Descriptor: | Galectin-8, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J.Y, Si, Y.L. | Deposit date: | 2016-09-28 | Release date: | 2016-12-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Crystallization of Galectin-8 Linker Reveals Intricate Relationship between the N-terminal Tail and the Linker. Int J Mol Sci, 17, 2016
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5GZK
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![BU of 5gzk by Molmil](/molmil-images/mine/5gzk) | Endo-beta-1,2-glucanase from Chitinophaga pinensis - sophorotriose and glucose complex | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | Authors: | Abe, K, Nakajima, M, Arakawa, T, Fushinobu, S, Taguchi, H. | Deposit date: | 2016-09-28 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Biochemical and structural analyses of a bacterial endo-beta-1,2-glucanase reveal a new glycoside hydrolase family J. Biol. Chem., 292, 2017
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5GKK
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3KXV
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![BU of 3kxv by Molmil](/molmil-images/mine/3kxv) | Structure of complement Factor H variant Q1139A | Descriptor: | Complement factor H, SULFATE ION | Authors: | Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. | Deposit date: | 2009-12-04 | Release date: | 2010-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.004 Å) | Cite: | Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010
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3KV6
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![BU of 3kv6 by Molmil](/molmil-images/mine/3kv6) | Structure of KIAA1718, human Jumonji demethylase, in complex with alpha-ketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1D, ... | Authors: | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | Deposit date: | 2009-11-29 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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5H04
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![BU of 5h04 by Molmil](/molmil-images/mine/5h04) | Crystal structure of an ADP-ribosylating toxin BECa of a novel binary enterotoxin of C. perfringens with NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Binary enterotoxin of Clostridium perfringens component a | Authors: | Kawahara, K, Yonogi, S, Munetomo, R, Oki, H, Yoshida, T, Ohkubo, T, Kumeda, Y, Matsuda, S, Kodama, T, Iida, T, Nakamura, S. | Deposit date: | 2016-10-03 | Release date: | 2016-11-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.825 Å) | Cite: | Crystal structure of the ADP-ribosylating component of BEC, the binary enterotoxin of Clostridium perfringens. Biochem.Biophys.Res.Commun., 480, 2016
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5GKX
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![BU of 5gkx by Molmil](/molmil-images/mine/5gkx) | Crystal structure of TON_0340, apo form | Descriptor: | PHOSPHATE ION, Uncharacterized protein | Authors: | Lee, S.G, Sohn, Y.S, Oh, B.H. | Deposit date: | 2016-07-07 | Release date: | 2016-12-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Identification of a Highly Conserved Hypothetical Protein TON_0340 as a Probable Manganese-Dependent Phosphatase. PLoS ONE, 11, 2016
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5H0G
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![BU of 5h0g by Molmil](/molmil-images/mine/5h0g) | Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-N,4-dimethylpentanamide | Descriptor: | (2~{S})-2-[[4-[4-azanyl-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]amino]-~{N},4-dimethyl-pentanamide, Tyrosine-protein kinase HCK | Authors: | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | Deposit date: | 2016-10-04 | Release date: | 2017-10-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen. Bioorg. Med. Chem., 25, 2017
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5GLB
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![BU of 5glb by Molmil](/molmil-images/mine/5glb) | Crystal structure of the class A beta-lactamase PenL-tTR10 in complex with CBA | Descriptor: | Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | Authors: | Choi, J.M, Yi, H, Kim, H.S, Lee, S.H. | Deposit date: | 2016-07-10 | Release date: | 2017-02-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | High adaptability of the omega loop underlies the substrate-spectrum-extension evolution of a class A beta-lactamase, PenL Sci Rep, 6, 2016
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3KYL
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![BU of 3kyl by Molmil](/molmil-images/mine/3kyl) | |
6XQF
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![BU of 6xqf by Molmil](/molmil-images/mine/6xqf) | Crystal structure of SCLam E144S mutant, a non-specific endo-beta-1,3(4)-glucanase from family GH16, co-crystallized with 1,3-beta-D-cellotriosyl-glucose, presenting a 1,3-beta-D-cellobiosyl-glucose at active site | Descriptor: | CALCIUM ION, GH16 family protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose | Authors: | Liberato, M.V, Squina, F. | Deposit date: | 2020-07-09 | Release date: | 2021-02-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Insights into the dual cleavage activity of the GH16 laminarinase enzyme class on beta-1,3 and beta-1,4 glycosidic bonds. J.Biol.Chem., 296, 2021
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5H0T
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![BU of 5h0t by Molmil](/molmil-images/mine/5h0t) | Crystal structure of proliferating cell nuclear antigen from Leishmania donovani at 2.73 Angstrom resolution | Descriptor: | DI(HYDROXYETHYL)ETHER, Proliferating cell nuclear antigen | Authors: | Singh, P.K, Yadav, S.P, Sharma, P.S, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2016-10-06 | Release date: | 2016-11-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structure and binding studies of proliferating cell nuclear antigen from Leishmania donovani. Biochim. Biophys. Acta, 1865, 2017
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7NMN
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![BU of 7nmn by Molmil](/molmil-images/mine/7nmn) | Rabbit HCN4 stabilised in amphipol A8-35 | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Rabbit HCN4 | Authors: | Chaves-Sanjuan, A. | Deposit date: | 2021-02-23 | Release date: | 2021-06-30 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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