5FGB
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![BU of 5fgb by Molmil](/molmil-images/mine/5fgb) | Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC33.4 | Descriptor: | Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, GLYCEROL, ... | Authors: | Girard-Blanc, C, Rey, F.A, Krey, T. | Deposit date: | 2015-12-20 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Antibody Response to Hypervariable Region 1 Interferes with Broadly Neutralizing Antibodies to Hepatitis C Virus. J.Virol., 90, 2016
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6ENR
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![BU of 6enr by Molmil](/molmil-images/mine/6enr) | |
5JPH
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![BU of 5jph by Molmil](/molmil-images/mine/5jph) | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus in complex with CoA | Descriptor: | Acetyltransferase SACOL1063, CHLORIDE ION, COENZYME A | Authors: | Majorek, K.A, Osinski, T, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-05-03 | Release date: | 2016-06-29 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria. Biochim.Biophys.Acta, 1865, 2016
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5JQ4
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![BU of 5jq4 by Molmil](/molmil-images/mine/5jq4) | Structure of a GNAT acetyltransferase SACOL1063 from Staphylococcus aureus | Descriptor: | 1,2-ETHANEDIOL, Acetyltransferase SACOL1063, CHLORIDE ION, ... | Authors: | Majorek, K.A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-05-04 | Release date: | 2016-06-29 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria. Biochim.Biophys.Acta, 1865, 2016
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4AGD
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![BU of 4agd by Molmil](/molmil-images/mine/4agd) | CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH SUNITINIB (SU11248) (N-2-diethylaminoethyl)-5-((Z)-(5- fluoro-2-oxo-1H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3- carboxamide) | Descriptor: | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 | Authors: | McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A. | Deposit date: | 2012-01-26 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
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6GSD
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![BU of 6gsd by Molmil](/molmil-images/mine/6gsd) | Plantago Major multifunctional oxidoreductase in complex with progesterone and NADP+ | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROGESTERONE, Progesterone 5-beta-reductase | Authors: | Fellows, R, Silva, C, Russo, C.M, Lee, S.G, Jez, J.M, Chisholm, J.D, Zubieta, C, Nanao, M. | Deposit date: | 2018-06-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A multisubstrate reductase from Plantago major: structure-function in the short chain reductase superfamily. Sci Rep, 8, 2018
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3KW0
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2VNG
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![BU of 2vng by Molmil](/molmil-images/mine/2vng) | Family 51 carbohydrate binding module from a family 98 glycoside hydrolase produced by Clostridium perfringens in complex with blood group A-trisaccharide ligand. | Descriptor: | CALCIUM ION, CPE0329, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose | Authors: | Gregg, K.J, Finn, R, Abbott, D.W, Boraston, A.B. | Deposit date: | 2008-02-04 | Release date: | 2008-02-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Divergent Modes of Glycan Recognition by a New Family of Carbohydrate-Binding Modules J.Biol.Chem., 283, 2008
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4AG8
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![BU of 4ag8 by Molmil](/molmil-images/mine/4ag8) | CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH AXITINIB (AG-013736) (N-Methyl-2-(3-((E)-2-pyridin-2-yl-vinyl)-1H- indazol-6-ylsulfanyl)-benzamide) | Descriptor: | AXITINIB, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 | Authors: | McTigue, M, Wickersham, J, Pinko, C, Kania, R.S, Bender, S. | Deposit date: | 2012-01-24 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
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4AGC
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![BU of 4agc by Molmil](/molmil-images/mine/4agc) | CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH AXITINIB (AG-013736) (N-Methyl-2-(3-((E)-2-pyridin-2-yl- vinyl)-1H-indazol-6-ylsulfanyl)-benzamide) | Descriptor: | AXITINIB, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 | Authors: | Mctigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Kania, R.S. | Deposit date: | 2012-01-26 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
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4ASD
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![BU of 4asd by Molmil](/molmil-images/mine/4asd) | Crystal Structure of VEGFR2 (Juxtamembrane and Kinase Domains) in Complex with SORAFENIB (BAY 43-9006) | Descriptor: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 | Authors: | McTigue, M, Deng, Y, Ryan, K, Brooun, A, Diehl, W, Stewart, A. | Deposit date: | 2012-04-30 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Molecular Conformations, Interactions, and Properties Associated with Drug Efficiency and Clinical Performance Among Vegfr Tk Inhibitors. Proc.Natl.Acad.Sci.USA, 109, 2012
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3VNE
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![BU of 3vne by Molmil](/molmil-images/mine/3vne) | Structure of the ebolavirus protein VP24 from Sudan | Descriptor: | Membrane-associated protein VP24 | Authors: | Zhang, A.P.P. | Deposit date: | 2012-01-12 | Release date: | 2012-04-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold Plos Pathog., 8, 2012
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6EEJ
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![BU of 6eej by Molmil](/molmil-images/mine/6eej) | Streptomyces bingchenggensis Aldolase-Dehydratase in covalent complex with dienone product. | Descriptor: | (3E,5E)-6-(4-nitrophenyl)-2-oxohexa-3,5-dienoic acid, Acetoacetate decarboxylase, FORMIC ACID, ... | Authors: | Mydy, L.S, Silvaggi, N.R. | Deposit date: | 2018-08-14 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Mechanistic Studies of theStreptomyces bingchenggensisAldolase-Dehydratase: Implications for Substrate and Reaction Specificity in the Acetoacetate Decarboxylase-like Superfamily. Biochemistry, 58, 2019
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5EL1
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![BU of 5el1 by Molmil](/molmil-images/mine/5el1) | |
5EMU
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![BU of 5emu by Molmil](/molmil-images/mine/5emu) | |
6EP9
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1AUP
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![BU of 1aup by Molmil](/molmil-images/mine/1aup) | GLUTAMATE DEHYDROGENASE | Descriptor: | NAD-SPECIFIC GLUTAMATE DEHYDROGENASE | Authors: | Baker, P.J, Waugh, M.L, Stillman, T.J, Turnbull, A.P, Rice, D.W. | Deposit date: | 1997-09-01 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Determinants of substrate specificity in the superfamily of amino acid dehydrogenases. Biochemistry, 36, 1997
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5NRA
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![BU of 5nra by Molmil](/molmil-images/mine/5nra) | Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 7g | Descriptor: | 1-(5-azanyl-4~{H}-1,2,4-triazol-3-yl)-~{N}-[2-(4-bromophenyl)ethyl]-~{N}-(2-methylpropyl)piperidin-4-amine, Chitotriosidase-1, GLYCEROL | Authors: | Mazur, M, Olczak, J, Olejniczak, S, Koralewski, R, Czestkowski, W, Jedrzejczak, A, Golab, J, Dzwonek, K, Dymek, B, Sklepkiewicz, P, Zagozdzon, A, Noonan, T, Mahboubi, K, Conway, B, Sheeler, R, Beckett, P, Hungerford, W.M, Podjarny, A, Mitschler, A, Cousido-Siah, A, Fadel, F, Golebiowski, A. | Deposit date: | 2017-04-22 | Release date: | 2018-03-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.267 Å) | Cite: | Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma. J. Med. Chem., 61, 2018
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6IFY
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![BU of 6ify by Molmil](/molmil-images/mine/6ify) | Type III-A Csm complex, Cryo-EM structure of Csm-CTR1 | Descriptor: | CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-21 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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6IFL
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![BU of 6ifl by Molmil](/molmil-images/mine/6ifl) | Cryo-EM structure of type III-A Csm-NTR complex | Descriptor: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | Authors: | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | Deposit date: | 2018-09-20 | Release date: | 2018-12-12 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
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1JPM
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![BU of 1jpm by Molmil](/molmil-images/mine/1jpm) | L-Ala-D/L-Glu Epimerase | Descriptor: | GLYCEROL, L-Ala-D/L-Glu Epimerase, MAGNESIUM ION | Authors: | Gulick, A.M, Schmidt, D.M.Z, Gerlt, J.A, Rayment, I. | Deposit date: | 2001-08-02 | Release date: | 2001-12-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry, 40, 2001
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3VNF
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![BU of 3vnf by Molmil](/molmil-images/mine/3vnf) | Structure of the ebolavirus protein VP24 from Sudan | Descriptor: | Membrane-associated protein VP24 | Authors: | Zhang, A.P.P. | Deposit date: | 2012-01-12 | Release date: | 2012-04-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold Plos Pathog., 8, 2012
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5NLV
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![BU of 5nlv by Molmil](/molmil-images/mine/5nlv) | Brag2 Sec7-PH (390-763) | Descriptor: | IQ motif and SEC7 domain-containing protein 1 | Authors: | Nawrotek, A, Cherfils, J. | Deposit date: | 2017-04-05 | Release date: | 2017-09-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5MG8
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![BU of 5mg8 by Molmil](/molmil-images/mine/5mg8) | Crystal structure of the S.pombe Smc5/6 hinge domain | Descriptor: | GLYCEROL, SULFATE ION, Structural maintenance of chromosomes protein 5, ... | Authors: | Alt, A, Pearl, L.H, Oliver, A.W. | Deposit date: | 2016-11-21 | Release date: | 2017-02-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nat Commun, 8, 2017
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5MAL
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![BU of 5mal by Molmil](/molmil-images/mine/5mal) | |