2BFX
| Mechanism of Aurora-B activation by INCENP and inhibition by Hesperadin. | Descriptor: | AURORA KINASE B-A, INNER CENTROMERE PROTEIN A | Authors: | Sessa, F, Mapelli, M, Ciferri, C, Tarricone, C, Areces, L.B, Schneider, T.R, Stukenberg, P.T, Musacchio, A. | Deposit date: | 2004-12-15 | Release date: | 2005-05-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanism of Aurora B Activation by Incenp and Inhibition by Hesperadin Mol.Cell, 18, 2005
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2BRS
| EMBP Heparin complex | Descriptor: | 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, EOSINOPHIL-GRANULE MAJOR BASIC PROTEIN, SULFATE ION | Authors: | Swaminathan, G.J, Myszka, D.G, Katsamba, P.S, Ohnuki, L.E, Gleich, G.J, Acharya, K.R. | Deposit date: | 2005-05-11 | Release date: | 2005-10-26 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Eosinophil-Granule Major Basic Protein, a C-Type Lectin, Binds Heparin Biochemistry, 44, 2005
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1C4D
| GRAMICIDIN CSCL COMPLEX | Descriptor: | CESIUM ION, CHLORIDE ION, GRAMICIDIN A, ... | Authors: | Wallace, B.A. | Deposit date: | 1999-06-04 | Release date: | 2000-01-03 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Gramicidin Pore: Crystal Structure of a Cesium Complex. Science, 241, 1988
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2BZY
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1Z9J
| Photosynthetic Reaction Center from Rhodobacter sphaeroides | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... | Authors: | Thielges, M, Uyeda, G, Camara-Artigas, A, Kalman, L, Williams, J.C, Allen, J.P. | Deposit date: | 2005-04-02 | Release date: | 2005-06-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Design of a Redox-Linked Active Metal Site: Manganese Bound to Bacterial Reaction Centers at a Site Resembling That of Photosystem II Biochemistry, 44, 2005
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1C4Z
| STRUCTURE OF AN E6AP-UBCH7 COMPLEX: INSIGHTS INTO THE UBIQUITINATION PATHWAY | Descriptor: | UBIQUITIN CONJUGATING ENZYME E2, UBIQUITIN-PROTEIN LIGASE E3A | Authors: | Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P. | Deposit date: | 1999-10-14 | Release date: | 1999-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science, 286, 1999
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2BU8
| crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DICHLORO-ACETIC ACID, MAGNESIUM ION, ... | Authors: | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | Deposit date: | 2005-06-08 | Release date: | 2006-02-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands. Biochemistry, 45, 2006
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2BV6
| Crystal structure of MgrA, a global regulator and major virulence determinant in Staphylococcus aureus | Descriptor: | HTH-TYPE TRANSCRIPTIONAL REGULATOR MGRA, SULFATE ION | Authors: | Chen, P.R, Bae, T, Williams, W.A, Duguid, E.M, Rice, P.A, Schneewind, O, He, C. | Deposit date: | 2005-06-22 | Release date: | 2006-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | An Oxidation-Sensing Mechanism is Used by the Global Regulator Mgra in Staphylococcus Aureus. Nat.Chem.Biol., 2, 2006
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1RDY
| T-STATE STRUCTURE OF THE ARG 243 TO ALA MUTANT OF PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE | Authors: | Stec, B, Abraham, R, Giroux, E, Kantrowitz, E.R. | Deposit date: | 1996-05-17 | Release date: | 1997-01-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the active site mutant (Arg-243-->Ala) in the T and R allosteric states of pig kidney fructose-1,6-bisphosphatase expressed in Escherichia coli. Protein Sci., 5, 1996
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1REE
| ENDO-1,4-BETA-XYLANASE II COMPLEX WITH 3,4-EPOXYBUTYL-BETA-D-XYLOSIDE | Descriptor: | (3S)-3-hydroxybutyl beta-D-xylopyranoside, BENZOIC ACID, ENDO-1,4-BETA-XYLANASE II | Authors: | Rouvinen, J, Havukainen, R, Torronen, A. | Deposit date: | 1995-12-21 | Release date: | 1997-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Covalent binding of three epoxyalkyl xylosides to the active site of endo-1,4-xylanase II from Trichoderma reesei. Biochemistry, 35, 1996
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2BUX
| Crystal Structure of Protocatechuate 3,4-Dioxygenase from Acinetobacter Sp. ADP1 Mutant R133H | Descriptor: | FE (III) ION, HYDROXIDE ION, PROTOCATECHUATE 3,4-DIOXYGENASE ALPHA CHAIN, ... | Authors: | Vetting, M.W, Valley, M.P, D'Argenio, D.A, Ornston, L.N, Lipscomb, J.D, Ohlendorf, D.H. | Deposit date: | 2005-06-20 | Release date: | 2006-10-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic Studies of Intradiol Dioxygenases. Phd Thesis, 2001
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1Y6O
| Crystal structure of disulfide engineered porcine pancreatic phospholipase A2 to group-X isozyme in complex with inhibitor MJ33 and phosphate ions | Descriptor: | 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Yu, B.Z, Pan, Y.H, Jassen, M.J.W, Bahnson, B.J, Jain, M.K. | Deposit date: | 2004-12-06 | Release date: | 2005-03-22 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns. Biochemistry, 44, 2005
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2E7T
| Crystal structure of basic winged bean lectin in complex with a blood group trisaccharide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Basic agglutinin, ... | Authors: | Kulkarni, K.A, Katiyar, S, Surolia, A, Vijayan, M, Suguna, K. | Deposit date: | 2007-01-13 | Release date: | 2007-06-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Generation of blood group specificity: New insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin Proteins, 68, 2007
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1RE2
| HUMAN LYSOZYME LABELLED WITH TWO 2',3'-EPOXYPROPYL BETA-GLYCOSIDE OF N-ACETYLLACTOSAMINE | Descriptor: | GLYCEROL, PROTEIN (LYSOZYME), beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Muraki, M, Harata, K, Sugita, N, Sato, K. | Deposit date: | 1998-11-05 | Release date: | 1999-05-05 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Dual affinity labeling of the active site of human lysozyme with an N-acetyllactosamine derivative: first ligand assisted recognition of the second ligand. Biochemistry, 38, 1999
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1YFW
| Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and O2 | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate-3,4-dioxygenase, 4-CHLORO-3-HYDROXYANTHRANILIC ACID, ... | Authors: | Zhang, Y, Colabroy, K.L, Begley, T.P, Ealick, S.E. | Deposit date: | 2005-01-04 | Release date: | 2005-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Studies on 3-Hydroxyanthranilate-3,4-dioxygenase: The Catalytic Mechanism of a Complex Oxidation Involved in NAD Biosynthesis. Biochemistry, 44, 2005
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1REF
| ENDO-1,4-BETA-XYLANASE II COMPLEX WITH 2,3-EPOXYPROPYL-BETA-D-XYLOSIDE | Descriptor: | (2R)-oxiran-2-ylmethyl beta-D-xylopyranoside, BENZOIC ACID, ENDO-1,4-BETA-XYLANASE II | Authors: | Rouvinen, J, Havukainen, R, Torronen, A. | Deposit date: | 1995-12-21 | Release date: | 1997-01-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Covalent binding of three epoxyalkyl xylosides to the active site of endo-1,4-xylanase II from Trichoderma reesei. Biochemistry, 35, 1996
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1REX
| NATIVE HUMAN LYSOZYME | Descriptor: | LYSOZYME | Authors: | Muraki, M, Harata, K. | Deposit date: | 1996-08-21 | Release date: | 1997-02-12 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Origin of carbohydrate recognition specificity of human lysozyme revealed by affinity labeling. Biochemistry, 35, 1996
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1YGH
| HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE | Descriptor: | GLYCEROL, PROTEIN (TRANSCRIPTIONAL ACTIVATOR GCN5) | Authors: | Trievel, R.C, Rojas, J.R, Sterner, D.E, Venkataramani, R, Wang, L, Zhou, J, Allis, C.D, Berger, S.L, Marmorstein, R. | Deposit date: | 1999-05-27 | Release date: | 1999-08-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. Proc.Natl.Acad.Sci.USA, 96, 1999
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2EKY
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1C4K
| ORNITHINE DECARBOXYLASE MUTANT (GLY121TYR) | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, PROTEIN (ORNITHINE DECARBOXYLASE), PYRIDOXAL-5'-PHOSPHATE | Authors: | Vitali, J, Hackert, M.L. | Deposit date: | 1999-08-26 | Release date: | 2000-02-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional structure of the Gly121Tyr dimeric form of ornithine decarboxylase from Lactobacillus 30a. Acta Crystallogr.,Sect.D, 55, 1999
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2EA7
| Crystal Structure of Adzuki Bean 7S Globulin-1 | Descriptor: | 7S globulin-1, ACETIC ACID, CALCIUM ION | Authors: | Fukuda, T, Mikami, B, Utsumi, S. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Characterization and crystallography of recombinant 7S globulins of Adzuki bean and structure-function relationships with 7S globulins of various crops. J.Agric.Food Chem., 56, 2008
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1RN1
| THREE-DIMENSIONAL STRUCTURE OF GLN 25-RIBONUCLEASE T1 AT 1.84 ANGSTROMS RESOLUTION: STRUCTURAL VARIATIONS AT THE BASE RECOGNITION AND CATALYTIC SITES | Descriptor: | RIBONUCLEASE T1 ISOZYME, SULFATE ION | Authors: | Arni, R.K, Pal, G.P, Ravichandran, K.G, Tulinsky, A, Walz Junior, F.G, Metcalf, P. | Deposit date: | 1991-11-22 | Release date: | 1994-01-31 | Last modified: | 2024-10-23 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Three-dimensional structure of Gln25-ribonuclease T1 at 1.84-A resolution: structural variations at the base recognition and catalytic sites. Biochemistry, 31, 1992
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1YAG
| STRUCTURE OF THE YEAST ACTIN-HUMAN GELSOLIN SEGMENT 1 COMPLEX | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Vorobiev, S, Strokopytov, B, Frieden, C, Almo, S.C. | Deposit date: | 1998-10-09 | Release date: | 1999-10-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure of nonvertebrate actin: Implications for the ATP
hydrolytic mechanism Proc.Natl.Acad.Sci.USA, 100, 2003
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1YAK
| Complex of Bacillus subtilis TenA with 4-amino-2-methyl-5-hydroxymethylpyrimidine | Descriptor: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, Transcriptional activator tenA | Authors: | Toms, A.V, Haas, A.L, Park, J.-H, Begley, T.P, Ealick, S.E. | Deposit date: | 2004-12-17 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II. Biochemistry, 44, 2005
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2EO5
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