5ZQH
 
 | | Crystal structure of Streptococcus transcriptional regulator | | Descriptor: | PadR family transcriptional regulator | | Authors: | Kim, M, Hong, M. | | Deposit date: | 2018-04-19 | | Release date: | 2019-05-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure-based functional analysis of a PadR transcription factor from Streptococcus pneumoniae and characteristic features in the PadR subfamily-2.
Biochem.Biophys.Res.Commun., 532, 2020
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3TOC
 | | Crystal structure of Streptococcus pyogenes Csn2 | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Putative uncharacterized protein | | Authors: | Bae, E, Jung, D.K, Koo, Y. | | Deposit date: | 2011-09-05 | | Release date: | 2012-05-30 | | Method: | X-RAY DIFFRACTION (2.201 Å) | | Cite: | Crystal Structure of Streptococcus pyogenes Csn2 Reveals Calcium-Dependent Conformational Changes in Its Tertiary and Quaternary Structure
Plos One, 7, 2012
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1PM6
 | | Solution Structure of Full-Length Excisionase (Xis) from Bacteriophage HK022 | | Descriptor: | Excisionase | | Authors: | Rogov, V.V, Luecke, C, Muresanu, L, Wienk, H, Kleinhaus, I, Werner, K, Loehr, F, Pristovsek, P, Rueterjans, H. | | Deposit date: | 2003-06-10 | | Release date: | 2003-12-30 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure and stability of the full-length excisionase from bacteriophage HK022.
Eur.J.Biochem., 270, 2003
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1TBA
 | | SOLUTION STRUCTURE OF A TBP-TAFII230 COMPLEX: PROTEIN MIMICRY OF THE MINOR GROOVE SURFACE OF THE TATA BOX UNWOUND BY TBP, NMR, 25 STRUCTURES | | Descriptor: | TRANSCRIPTION INITIATION FACTOR IID 230K CHAIN, TRANSCRIPTION INITIATION FACTOR TFIID | | Authors: | Liu, D, Ishima, R, Tong, K.I, Bagby, S, Kokubo, T, Muhandiram, D.R, Kay, L.E, Nakatani, Y, Ikura, M. | | Deposit date: | 1998-08-16 | | Release date: | 1999-08-16 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP.
Cell(Cambridge,Mass.), 94, 1998
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7DG2
 | | Nse1-Nse3-Nse4 complex | | Descriptor: | ACETATE ION, GLYCEROL, MAGE domain-containing protein, ... | | Authors: | Cho, Y, Jo, A. | | Deposit date: | 2020-11-10 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure Basis for Shaping the Nse4 Protein by the Nse1 and Nse3 Dimer within the Smc5/6 Complex.
J.Mol.Biol., 433, 2021
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1N0O
 | | NMR Structure of d(CCAAGGXCTTGGG), X is a 3'-phosphoglycolate, 5'-phosphate gapped lesion, 10 structures | | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, 5'-D(*CP*CP*AP*AP*GP*G)-3', 5'-D(*CP*CP*CP*AP*AP*GP*GP*CP*CP*TP*TP*GP*G)-3', ... | | Authors: | Junker, H.-D, Hoehn, S.T, Bunt, R.C, Marathius, V, Chen, J, Turner, C.J, Stubbe, J. | | Deposit date: | 2002-10-14 | | Release date: | 2003-01-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Synthesis, Characterization, and Solution Structure of Tethered Oligonucleotides Containing an Internal 3'-Phosphoglycolate, 5'-Phosphate Gapped Lesion
Nucleic Acids Res., 30, 2002
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2F1N
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4QKQ
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3P56
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2CSB
 | | Crystal structure of Topoisomerase V from Methanopyrus kandleri (61 kDa fragment) | | Descriptor: | MAGNESIUM ION, Topoisomerase V | | Authors: | Taneja, B, Patel, A, Slesarev, A, Mondragon, A. | | Deposit date: | 2005-05-21 | | Release date: | 2006-01-31 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases
Embo J., 25, 2006
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1I1S
 | | SOLUTION STRUCTURE OF THE TRANSCRIPTIONAL ACTIVATION DOMAIN OF THE BACTERIOPHAGE T4 PROTEIN MOTA | | Descriptor: | MOTA | | Authors: | Li, N, Zhang, W, White, S.W, Kriwacki, R.W. | | Deposit date: | 2001-02-02 | | Release date: | 2001-02-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the transcriptional activation domain of the bacteriophage T4 protein, MotA.
Biochemistry, 40, 2001
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2YDI
 | | Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas | | Descriptor: | 5-[4-(2-DIMETHYLAMINOETHYLOXY)PHENYL]-2-UREIDO-THIOPHENE-3-CARBOXAMIDE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION | | Authors: | Read, J.A, Breed, J, Haye, H, McCall, E, Rowsell, S, Vallentine, A, White, A. | | Deposit date: | 2011-03-21 | | Release date: | 2012-04-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(Piperidin-3-Yl)-3-Ureidothiophene-2-Carboxamide (Azd7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas.
J.Med.Chem., 55, 2012
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5IP8
 | | Lambda-Ru(TAP)2dppz bound to d(CCGGCTCCGG) | | Descriptor: | BARIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*GP*CP*CP*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*CP*TP*CP*CP*GP*G)-3'), ... | | Authors: | Souter, J.E, Hall, J.P, Cardin, C.J. | | Deposit date: | 2016-03-09 | | Release date: | 2017-03-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Sequence specific binding of light activated Ru-polypyridyls
To Be Published
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2LSN
 | | Solution structure of PFV RNase H domain | | Descriptor: | RNase H | | Authors: | Leo, B, Schweimer, K, Woehrl, B. | | Deposit date: | 2012-05-03 | | Release date: | 2012-10-17 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding.
Retrovirology, 9, 2012
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1S2R
 | | A High Resolution Crystal Structure of [d(CGCAAATTTGCG)]2 | | Descriptor: | 5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*TP*GP*CP*G)-3', SPERMINE | | Authors: | Woods, K.K, Maehigashi, T, Howerton, S.B, Tannenbaum, S, Williams, L.D. | | Deposit date: | 2004-01-09 | | Release date: | 2005-01-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | High-resolution structure of an extended A-tract: [d(CGCAAATTTGCG)]2.
J.Am.Chem.Soc., 126, 2004
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4BUL
 | | Novel hydroxyl tricyclics (e.g. GSK966587) as potent inhibitors of bacterial type IIA topoisomerases | | Descriptor: | (S)-4-((4-(((2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methyl)amino)piperidin-1-yl)methyl)-3-fluoro-4-hydroxy-4H-pyrrolo[3,2,1-de][1,5]naphthyridin-7(5H)-one, 5'-D(*AP*GP*CP*CP*GP*TP*AP*GP*GP*TP*AP*CP*AP*CP *CP*GP*CP*AP*C)-3', 5'-D(*TP*GP*TP*GP*CP*GP*GP*TP*GP*TP*AP*CP*CP*TP *AP*CP*GP*GP*CP*T)-3', ... | | Authors: | Miles, T.J, Hennessy, A.J, Bax, B, Brooks, G, Brown, B.S, Brown, P, Cailleau, N, Chen, D, Dabbs, S, Davies, D.T, Esken, J.M, Giordano, I, Hoover, J.L, Huang, J, Jones, G.E, Sukmar, S.K.K, Spitzfaden, C, Markwell, R.E, Minthorn, E.A, Rittenhouse, S, Gwynn, M.N, Pearson, N.D. | | Deposit date: | 2013-06-20 | | Release date: | 2013-08-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Novel Hydroxyl Tricyclics (E.G., Gsk966587) as Potent Inhibitors of Bacterial Type Iia Topoisomerases.
Bioorg.Med.Chem.Lett., 23, 2013
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5VAC
 | | Crystal Structure of ATXR5 SET domain in complex with K36me3 histone H3 peptide | | Descriptor: | DIMETHYL SULFOXIDE, Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, ... | | Authors: | Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.F. | | Deposit date: | 2017-03-24 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.949 Å) | | Cite: | Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
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2IO5
 | | Crystal structure of the CIA- histone H3-H4 complex | | Descriptor: | ASF1A protein, Histone H3.1, Histone H4 | | Authors: | Natsume, R, Akai, Y, Horikoshi, M, Senda, T. | | Deposit date: | 2006-10-10 | | Release date: | 2007-02-27 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4.
Nature, 446, 2007
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3IBP
 | | The Crystal Structure of the Dimerization Domain of Escherichia coli Structural Maintenance of Chromosomes Protein MukB | | Descriptor: | AMMONIUM ION, Chromosome partition protein mukB | | Authors: | Li, Y, Schoeffler, A.J, Berger, J.M, Oakley, M.G. | | Deposit date: | 2009-07-16 | | Release date: | 2010-01-26 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.099 Å) | | Cite: | The crystal structure of the hinge domain of the Escherichia coli structural maintenance of chromosomes protein MukB.
J.Mol.Biol., 395, 2010
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2N26
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5KDM
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5VAH
 | | Crystal structure of ATXR5 SET domain in complex with histone H3 di-methylated on R26 | | Descriptor: | Histone H3.2, Probable Histone-lysine N-methyltransferase ATXR5, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Bergamin, E, Sarvan, S, Malette, J, Eram, M, Yeung, S, Mongeon, V, Joshi, M, Brunzelle, J.S, Michaels, S.D, Blais, A, Vedadi, M, Couture, J.-F. | | Deposit date: | 2017-03-26 | | Release date: | 2017-04-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
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8I4U
 | | Cryo-EM structure of 5-subunit Smc5/6 hinge region | | Descriptor: | E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6 | | Authors: | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | | Deposit date: | 2023-01-21 | | Release date: | 2024-06-26 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (6.73 Å) | | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms.
Nat.Struct.Mol.Biol., 2024
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8X5I
 | | tetramer Gabija with ATP (local refinement) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, MAGNESIUM ION | | Authors: | Li, J, Wang, Z, Wang, L. | | Deposit date: | 2023-11-17 | | Release date: | 2024-02-28 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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5VBC
 | | Crystal structure of ATXR5 in complex with histone H3.1 | | Descriptor: | DIMETHYL SULFOXIDE, Histone H3.1 peptide, Probable Histone-lysine N-methyltransferase ATXR5, ... | | Authors: | Couture, J.-F, Bergamin, E. | | Deposit date: | 2017-03-29 | | Release date: | 2017-04-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular basis for the methylation specificity of ATXR5 for histone H3.
Nucleic Acids Res., 45, 2017
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