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6PZY
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BU of 6pzy by Molmil
CryoEM derived model of NA-73 Fab in complex with N9 Shanghai2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, NA-73 fragment antibody heavy chain, ...
Authors:Ward, A.B, Turner, H.L, Zhu, X.
Deposit date:2019-08-01
Release date:2019-12-04
Last modified:2023-04-05
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies.
Cell Host Microbe, 26, 2019
6XKP
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BU of 6xkp by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-270
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV07-270 Heavy Chain, CV07-270 Light Chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A.
Deposit date:2020-06-26
Release date:2020-10-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model.
Cell, 183, 2020
3HI6
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BU of 3hi6 by Molmil
Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57
Descriptor: Heavy chain of Fab fragment of AL-57 against alpha L I domain, Integrin alpha-L, MANGANESE (II) ION, ...
Authors:Zhang, H, Wang, J.
Deposit date:2009-05-19
Release date:2009-09-22
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1.
Proc.Natl.Acad.Sci.USA, 106, 2009
4Z8F
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BU of 4z8f by Molmil
Fab structure of antibody S1-15 in complex with ssDNA DNA, 5'-p5(dT)p-3'
Descriptor: 5'-D(P*TP*TP*TP*TP*T)-3', S1-15 Fab (IgG2b kappa) light chain, S1-15 Fab (IgG2b) heavy chain
Authors:Haji-Ghassemi, O, Evans, S.V.
Deposit date:2015-04-08
Release date:2015-06-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA.
J.Biol.Chem., 290, 2015
7F62
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BU of 7f62 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody chAb-25 (Focused refinement of S-RBD and chAb-25 region)
Descriptor: RBD-chAb-25, Heavy chain, Light chain, ...
Authors:Yang, T.J, Yu, P.Y, Wu, H.C, Hsu, S.T.D.
Deposit date:2021-06-24
Release date:2021-08-04
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure-guided antibody cocktail for prevention and treatment of COVID-19.
Plos Pathog., 17, 2021
5WB9
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BU of 5wb9 by Molmil
Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
Authors:Gohain, N, Tolbert, W, Pazgier, M.
Deposit date:2017-06-28
Release date:2018-05-23
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of Near-Pan-neutralizing Antibodies against HIV-1 by Deconvolution of Plasma Humoral Responses.
Cell, 173, 2018
7MDU
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BU of 7mdu by Molmil
BG505 SOSIP MD39 in complex with the monoclonal antibodies Rh.33104 mAb.1 and RM20A3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RM20A3 mAb Heavy Chain, ...
Authors:Antanasijevic, A, Ward, A.B.
Deposit date:2021-04-06
Release date:2022-01-26
Last modified:2022-02-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:From structure to sequence: Antibody discovery using cryoEM.
Sci Adv, 8, 2022
5I1C
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BU of 5i1c by Molmil
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FAB HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
7ZWF
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BU of 7zwf by Molmil
Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3
Descriptor: 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.132 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
6EHY
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BU of 6ehy by Molmil
scFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery
Descriptor: scFv antibody fragment
Authors:Hargreaves, D.
Deposit date:2017-09-15
Release date:2017-11-08
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:scFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery
To Be Published
3NTC
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BU of 3ntc by Molmil
Crystal structure of KD-247 Fab, an anti-V3 antibody that inhibits HIV-1 Entry
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Fab heavy chain, ...
Authors:Sarafianos, S.G, Kirby, K.A.
Deposit date:2010-07-03
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of clade-specific HIV-1 neutralization by humanized anti-V3 monoclonal antibody KD-247.
Faseb J., 29, 2015
8IPC
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BU of 8ipc by Molmil
The recombinant NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA14 tag inserted between the residues 181 and 184
Descriptor: Putative zinc metalloprotease aq_1964, The recombinantly-expressed heavy chain of the monoclonal antibody NZ-1, The recombinantly-expressed light chain of the monoclonal antibody NZ-1
Authors:Adachi, Y, Nogi, T.
Deposit date:2023-03-14
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recombinant production of antibody antigen-binding fragments with an N-terminal human growth hormone tag in mammalian cells.
Protein Expr.Purif., 208-209, 2023
4JO3
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BU of 4jo3 by Molmil
Crystal structure of rabbit mAb R20 Fab in complex with V3 C-terminus of HIV-1 Consensus B gp120
Descriptor: SULFATE ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
Authors:Pan, R.M, Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
6Z7Z
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BU of 6z7z by Molmil
Porcine insulin in complex with the analytical antibody OXI-005 Fab
Descriptor: Insulin, MAGNESIUM ION, OXI-005 Fab Heavy chain, ...
Authors:Johansson, E.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
4JO4
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BU of 4jo4 by Molmil
Crystal structure of rabbit mAb R20 Fab
Descriptor: PENTAETHYLENE GLYCOL, SULFATE ION, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
Authors:Pan, R.M, Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
6Z7W
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BU of 6z7w by Molmil
Human insulin in complex with the analytical antibody HUI-018 Fab
Descriptor: HUI-018 Fab Heavy Chain, Insulin, MAb 6H10 light chain
Authors:Johansson, E.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
1AJ7
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BU of 1aj7 by Molmil
IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Descriptor: 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN)
Authors:Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C.
Deposit date:1997-05-15
Release date:1997-11-12
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
6Z7X
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BU of 6z7x by Molmil
Insulin analytical antibody OXI-005 Fab
Descriptor: OXI-005 Fab Heavy chain, OXI-005 Fab Light chain
Authors:Johansson, E.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
6Z7Y
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BU of 6z7y by Molmil
Human insulin in complex with the analytical antibody OXI-005 Fab
Descriptor: Insulin, OXI-005 Fab Heavy chain, OXI-005 Fab Light chain
Authors:Johansson, E.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
4JO2
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BU of 4jo2 by Molmil
Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120
Descriptor: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ...
Authors:Pan, R.M, Kong, X.P.
Deposit date:2013-03-16
Release date:2013-07-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
1L7I
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BU of 1l7i by Molmil
Crystal Structure of the anti-ErbB2 Fab2C4
Descriptor: SULFATE ION, chimera of Fab2C4: "humanized" murine monoclonal antibody
Authors:Vajdos, F.F, Adams, C.W, Breece, T.N, Presta, L.G, de Vos, A.M, Sidhu, S.S.
Deposit date:2002-03-15
Release date:2002-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.
J.Mol.Biol., 320, 2002
6I9I
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BU of 6i9i by Molmil
Rift valley fever virus Gn in complex with a neutralizing antibody fragment
Descriptor: Glycoprotein, RV-Gn1 Heavy chain, RV-Gn1 Light chain
Authors:Allen, E.R, Bowden, T.A.
Deposit date:2018-11-23
Release date:2018-12-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:A Protective Monoclonal Antibody Targets a Site of Vulnerability on the Surface of Rift Valley Fever Virus.
Cell Rep, 25, 2018
1OCW
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BU of 1ocw by Molmil
Free conformation Ab2 of the IgE SPE-7
Descriptor: IMMUNOGLOBULIN E
Authors:James, L.C, Roversi, P, Tawfik, D.
Deposit date:2003-02-11
Release date:2004-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
3OJD
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BU of 3ojd by Molmil
Anti-Indolicidin monoclonal antibody V2D2 (Fab fragment)
Descriptor: Fab V2D2
Authors:Lomash, S, Salunke, D.M.
Deposit date:2010-08-22
Release date:2010-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:An antibody as surrogate receptor reveals determinants of activity of an innate immune peptide antibiotic
J.Biol.Chem., 285, 2010
4K23
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BU of 4k23 by Molmil
Structure of anti-uPAR Fab ATN-658
Descriptor: anti-uPAR antibody, heavy chain, light chain
Authors:Yuan, C, Huang, M, Chen, L.
Deposit date:2013-04-08
Release date:2014-02-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M)
Plos One, 9, 2014

224201

数据于2024-08-28公开中

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