5YRX
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![BU of 5yrx by Molmil](/molmil-images/mine/5yrx) | Crystal structure of a hypothetical protein Rv3716c from Mycobacterium tuberculosis | Descriptor: | 1,2-ETHANEDIOL, CADMIUM ION, Nucleoid-associated protein Rv3716c | Authors: | Deka, G, Gopalan, A, Prabhavathi, M, Savithri, H.S, Raja, A, Murthy, M.R.N. | Deposit date: | 2017-11-10 | Release date: | 2018-05-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and biophysical characterization of Rv3716c, a hypothetical protein from Mycobacterium tuberculosis Biochem. Biophys. Res. Commun., 495, 2018
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7A5I
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![BU of 7a5i by Molmil](/molmil-images/mine/7a5i) | Structure of the human mitoribosome with A- P-and E-site mt-tRNAs | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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6Z8X
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![BU of 6z8x by Molmil](/molmil-images/mine/6z8x) | X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3Leu), which contains leucyl amide in the side chain of Thy3 at N3. | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, Prothrombin, ... | Authors: | Troisi, R, Timofeev, E.N, Sica, F. | Deposit date: | 2020-06-02 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12. Mol Ther Nucleic Acids, 23, 2021
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5ZB8
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![BU of 5zb8 by Molmil](/molmil-images/mine/5zb8) | |
8OOK
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![BU of 8ook by Molmil](/molmil-images/mine/8ook) | |
8OOF
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![BU of 8oof by Molmil](/molmil-images/mine/8oof) | CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ... | Authors: | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | Deposit date: | 2023-04-05 | Release date: | 2023-07-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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8OOT
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![BU of 8oot by Molmil](/molmil-images/mine/8oot) | CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state2 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ... | Authors: | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | Deposit date: | 2023-04-05 | Release date: | 2023-07-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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1BL3
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![BU of 1bl3 by Molmil](/molmil-images/mine/1bl3) | CATALYTIC DOMAIN OF HIV-1 INTEGRASE | Descriptor: | INTEGRASE, MAGNESIUM ION | Authors: | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | Deposit date: | 1998-07-23 | Release date: | 1998-09-30 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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4IGK
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6W62
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![BU of 6w62 by Molmil](/molmil-images/mine/6w62) | Cryo-EM structure of Cas12i-crRNA complex | Descriptor: | Cas12i, crRNA | Authors: | Chang, L, Li, Z, Zhang, H. | Deposit date: | 2020-03-16 | Release date: | 2020-09-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Mechanisms for target recognition and cleavage by the Cas12i RNA-guided endonuclease. Nat.Struct.Mol.Biol., 27, 2020
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6XXC
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![BU of 6xxc by Molmil](/molmil-images/mine/6xxc) | Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 4 | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, Estrogen Related Receptor gamma phosphopeptide, ... | Authors: | Somsen, B.A, Ottmann, C. | Deposit date: | 2020-01-27 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
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4IFI
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6Z8V
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![BU of 6z8v by Molmil](/molmil-images/mine/6z8v) | X-ray structure of the complex between human alpha thrombin and a thrombin binding aptamer variant (TBA-3L), which contains 1-beta-D-lactopyranosyl residue in the side chain of Thy3 at N3. | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, POTASSIUM ION, Prothrombin, ... | Authors: | Troisi, R, Timofeev, E.N, Sica, F. | Deposit date: | 2020-06-02 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Expanding the recognition interface of the thrombin-binding aptamer HD1 through modification of residues T3 and T12. Mol Ther Nucleic Acids, 23, 2021
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1BQN
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![BU of 1bqn by Molmil](/molmil-images/mine/1bqn) | TYR 188 LEU HIV-1 RT/HBY 097 | Descriptor: | (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE | Authors: | Hsiou, Y, Das, K, Ding, J, Arnold, E. | Deposit date: | 1998-08-17 | Release date: | 1999-01-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance. J.Mol.Biol., 284, 1998
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1BQM
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![BU of 1bqm by Molmil](/molmil-images/mine/1bqm) | HIV-1 RT/HBY 097 | Descriptor: | (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE, REVERSE TRANSCRIPTASE | Authors: | Hsiou, Y, Das, K, Ding, J, Arnold, E. | Deposit date: | 1998-08-17 | Release date: | 1999-01-06 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of Tyr188Leu mutant and wild-type HIV-1 reverse transcriptase complexed with the non-nucleoside inhibitor HBY 097: inhibitor flexibility is a useful design feature for reducing drug resistance. J.Mol.Biol., 284, 1998
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3E5Q
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![BU of 3e5q by Molmil](/molmil-images/mine/3e5q) | Unbound Oxidised CprK | Descriptor: | Cyclic nucleotide-binding protein | Authors: | Levy, C. | Deposit date: | 2008-08-14 | Release date: | 2008-09-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
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5HXY
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![BU of 5hxy by Molmil](/molmil-images/mine/5hxy) | Crystal structure of XerA recombinase | Descriptor: | PHOSPHATE ION, Tyrosine recombinase XerA | Authors: | Hwang, K.Y, Nam, K.H. | Deposit date: | 2016-01-31 | Release date: | 2017-02-01 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Thermoplasma acidophilum XerA recombinase shows large C-shape clamp conformation and cis-cleavage mode for nucleophilic tyrosine FEBS Lett., 590, 2016
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1H7U
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![BU of 1h7u by Molmil](/molmil-images/mine/1h7u) | hPMS2-ATPgS | Descriptor: | MAGNESIUM ION, MISMATCH REPAIR ENDONUCLEASE PMS2, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Guarne, A, Junop, M.S, Yang, W. | Deposit date: | 2001-07-10 | Release date: | 2001-11-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and Function of the N-Terminal 40 kDa Fragment of Human Pms2: A Monomeric Ghl ATPase Embo J., 20, 2001
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3E9W
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1BHL
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![BU of 1bhl by Molmil](/molmil-images/mine/1bhl) | CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE | Descriptor: | HIV-1 INTEGRASE | Authors: | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | Deposit date: | 1998-06-10 | Release date: | 1998-10-14 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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1BI4
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![BU of 1bi4 by Molmil](/molmil-images/mine/1bi4) | CATALYTIC DOMAIN OF HIV-1 INTEGRASE | Descriptor: | INTEGRASE | Authors: | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | Deposit date: | 1998-06-22 | Release date: | 1998-11-04 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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1MM3
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![BU of 1mm3 by Molmil](/molmil-images/mine/1mm3) | Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding loop from WSTF | Descriptor: | Mi2-beta(Chromodomain helicase-DNA-binding protein 4) and transcription factor WSTF, ZINC ION | Authors: | Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. | Deposit date: | 2002-09-02 | Release date: | 2003-07-22 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
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2OUG
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![BU of 2oug by Molmil](/molmil-images/mine/2oug) | |
3E5X
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![BU of 3e5x by Molmil](/molmil-images/mine/3e5x) | OCPA complexed CprK | Descriptor: | (3-CHLORO-4-HYDROXYPHENYL)ACETIC ACID, Cyclic nucleotide-binding protein | Authors: | Levy, C. | Deposit date: | 2008-08-14 | Release date: | 2008-12-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator Mol.Microbiol., 70, 2008
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1NFI
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![BU of 1nfi by Molmil](/molmil-images/mine/1nfi) | I-KAPPA-B-ALPHA/NF-KAPPA-B COMPLEX | Descriptor: | I-KAPPA-B-ALPHA, NF-KAPPA-B P50, NF-KAPPA-B P65 | Authors: | Jacobs, M.D, Harrison, S.C. | Deposit date: | 1998-08-25 | Release date: | 1998-11-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of an IkappaBalpha/NF-kappaB complex. Cell(Cambridge,Mass.), 95, 1998
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