3E9W

X-Ray Crystal Structure of the hexamer DCACACG:Crystal grown in the presence of cobalt(III)hexammine Chloride.

Summary for 3E9W

• Entry DOI: 10.2210/pdb3e9w/pdb
• Descriptor: 5'-D(*CP*AP*CP*AP*CP*G)-3', 5'-D(*CP*GP*TP*GP*TP*G)-3' (3 entities in total)
• Functional Keywords: z double helix, dna
• Total number of polymer chains: 2
• Total formula weight: 3618.43

Authors

Venkadesh, S.,Mandal, P.K.,Gautham, N. (deposition date: 2008-08-24, release date: 2008-09-30, Last modification date: 2024-04-03)

Primary citation

Venkadesh, S.,Mandal, P.K.,Gautham, N.
The structure of d(CACACG).d(CGTGTG).
Acta Crystallogr.,Sect.F, 65:8-13, 2009

PubMed Abstract: The crystal structure of d(CACACG).d(CGTGTG) was solved to a resolution of 2.05 A in space group P2(1). The duplex assumes the left-handed Z-DNA structure. The presence of two A.T base pairs in the hexamer does not greatly affect the conformation. The most significant changes compared with the regular structure of Z-DNA are in the values of twist in the central portion of the helix. This variation, as well as others in the values of roll, inclination etc., follow the pattern observed previously in the structure of d(CGCACG).d(CGTGCG).

PubMed: 19153446
DOI: 10.1107/S1744309108037706

Experimental method

X-RAY DIFFRACTION (2.05 Å)