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8WUS
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BU of 8wus by Molmil
SpCas9-MMLV RT-pegRNA-target DNA complex (termination)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
7NKG
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BU of 7nkg by Molmil
Methyl-coenzyme M reductase from Methermicoccus shengliensis at 1.6-A resolution
Descriptor: 1-THIOETHANESULFONIC ACID, Coenzyme B, FACTOR 430, ...
Authors:Mueller, M, Wagner, T.
Deposit date:2021-02-18
Release date:2021-05-19
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights into the Methane-Generating Enzyme from a Methoxydotrophic Methanogen Reveal a Restrained Gallery of Post-Translational Modifications.
Microorganisms, 9, 2021
8WUU
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BU of 8wuu by Molmil
SpCas9-pegRNA-target DNA complex (pre-initiation)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (34-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
8WI2
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BU of 8wi2 by Molmil
RD-hMRP5-inward open
Descriptor: ATP-binding cassette sub-family C member 5, CYS-GLN-ASP-ALA-LEU-GLU-THR-ALA-ALA-ARG-ALA-GLU-GLY-LEU-SER-LEU-ASP-ALA-SER
Authors:Liu, Z.M, Huang, Y.
Deposit date:2023-09-24
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (4.06 Å)
Cite:Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
8XRT
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BU of 8xrt by Molmil
The crystal structure of a GH3 enzyme CcBgl3B
Descriptor: CALCIUM ION, GH3 enzyme CcBgl3B
Authors:Su, J.Y.
Deposit date:2024-01-08
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A trapped covalent intermediate as a key catalytic element in the hydrolysis of a GH3 beta-glucosidase: An X-ray crystallographic and biochemical study.
Int.J.Biol.Macromol., 265, 2024
8X5D
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BU of 8x5d by Molmil
The cryo-EM structure of the Mycobacterium tuberculosis CRISPR-Csm complex
Descriptor: CRISPR system Cms endoribonuclease Csm3, CRISPR system Cms protein Csm5, Csm2, ...
Authors:Liu, M.X, Li, Z.K.
Deposit date:2023-11-17
Release date:2024-03-06
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type-III-A structure of mycobacteria CRISPR-Csm complexes involving atypical crRNAs.
Int.J.Biol.Macromol., 260, 2024
9FZD
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BU of 9fzd by Molmil
Structure of OmpA-long in complex with nanobody Nb39
Descriptor: Nanobody 39, Outer membrane protein A
Authors:Ackle, F, Sorgenfrei, M, Seeger, M.A.
Deposit date:2024-07-05
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
To Be Published
8Z9Q
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BU of 8z9q by Molmil
Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-23
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.33 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
8Z9R
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BU of 8z9r by Molmil
Cryo-EM structure of Thogoto virus polymerase in a replication elongation-reception conformation
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-23
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
8YTO
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BU of 8yto by Molmil
Single-chain Fv antibody of E11 complex with NP-glycine
Descriptor: 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M.
Deposit date:2024-03-26
Release date:2024-07-03
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
8XP9
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BU of 8xp9 by Molmil
Crystal structure of d(ACGCCGT/ACGGCGT)
Descriptor: DNA (5'-D(P*AP*CP*GP*CP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*GP*CP*GP*T)-3')
Authors:Hou, M.H, Lin, S.M, Lin, Y.J, Neidle, S.
Deposit date:2024-01-03
Release date:2024-05-29
Last modified:2024-08-14
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation.
Nucleic Acids Res., 2024
8WUV
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BU of 8wuv by Molmil
SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ...
Authors:Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O.
Deposit date:2023-10-21
Release date:2024-06-05
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for pegRNA-guided reverse transcription by a prime editor.
Nature, 631, 2024
9CK0
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BU of 9ck0 by Molmil
Cocrystal of PPARg LBD and NFKBIB / IKBB peptide with agonist GW1929
Descriptor: (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, NF-kappa-B inhibitor beta, Peroxisome proliferator-activated receptor gamma
Authors:Nemetchek, M.D, McClelland, L.J, Hughes, T.S.
Deposit date:2024-07-08
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Cocrystal of PPARg LBD with NFKBIB / IKBB peptide containing N-anchor motif LxxLL and agonist GW1929
To Be Published
8XOO
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BU of 8xoo by Molmil
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Xu, X, Long, F.
Deposit date:2024-01-01
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (1.84 Å)
Cite:Structural insights into the Clp protein degradation machinery.
Mbio, 15, 2024
8YZ7
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BU of 8yz7 by Molmil
Crystal structure of DdrI, a CRP family protein from Deinococcus radiodurans
Descriptor: POTASSIUM ION, Transcriptional regulator, FNR/CRP family
Authors:Zhao, Y, Wang, Y.
Deposit date:2024-04-06
Release date:2024-07-03
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:cAMP-independent DNA binding of the CRP family protein DdrI from Deinococcus radiodurans .
Mbio, 15, 2024
7N02
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BU of 7n02 by Molmil
X-ray crystallographic structure model of Lactococcus lactis prolidase mutant D36S
Descriptor: Aminopeptidase P family protein, MANGANESE (II) ION
Authors:Xu, S, Grochulski, P, Tanaka, T.
Deposit date:2021-05-24
Release date:2021-06-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystallographic structure of recombinant Lactococcus lactis prolidase to support proposed structure-function relationships.
Biochim Biophys Acta Proteins Proteom, 1865, 2017
9FZC
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BU of 9fzc by Molmil
Structure of OmpA-short in complex with nanobody Nb01
Descriptor: CALCIUM ION, N-OCTANE, Nanobody 01, ...
Authors:Ackle, F, Sorgenfrei, M, Seeger, M.A.
Deposit date:2024-07-05
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Rapid detection and capture of clinical Escherichia coli strains mediated by OmpA-targeting nanobodies
To Be Published
8VYL
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BU of 8vyl by Molmil
The structure of Human Hemoglobin in Complex with Nanobody BtNbE11
Descriptor: ACETYL GROUP, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Grinter, R, Binks, S, Fox, D.
Deposit date:2024-02-08
Release date:2024-07-17
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The structure of a haemoglobin-nanobody complex reveals human beta-subunit-specific interactions.
Febs Lett., 2024
8VAE
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BU of 8vae by Molmil
Cryogenic electron microscopy structure of human serum albumin in complex with salicylic acid
Descriptor: 2-HYDROXYBENZOIC ACID, Serum albumin
Authors:Catalano, C, Lucier, K.W, To, D, Senko, S, Tran, N.L, Farwell, A.C, Silva, S.M, Dip, P.V, Poweleit, N, Scapin, G.
Deposit date:2023-12-11
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The CryoEM structure of human serum albumin in complex with ligands.
J.Struct.Biol., 216, 2024
8Z8J
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BU of 8z8j by Molmil
Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-22
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
9CA0
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BU of 9ca0 by Molmil
Human TOP3B-TDRD3 core complex in DNA pre-cleavage state
Descriptor: DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ...
Authors:Yang, X, Chen, X, Yang, W, Pommier, Y.
Deposit date:2024-06-16
Release date:2024-07-17
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
To Be Published
8YTP
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BU of 8ytp by Molmil
Single-chain Fv antibody of E11 complex with NP-glycine under reducing conditions
Descriptor: 2-[2-(3-nitro-4-oxidanyl-phenyl)ethanoylamino]ethanoic acid, Single-chain Fv antibody of E11
Authors:Yoshida, M, Hanazono, Y, Numoto, N, Ito, N, Oda, M.
Deposit date:2024-03-26
Release date:2024-07-03
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Affinity-matured antibody with a disulfide bond in H-CDR3 loop.
Arch.Biochem.Biophys., 758, 2024
8WQL
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BU of 8wql by Molmil
In situ PBS-PSII supercomplex from cyanobacterial Spirulina platensis
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:You, X, Zhang, X, Xiao, Y.N, Sun, S, Sui, S.F.
Deposit date:2023-10-11
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of in situ PBS-PSII supercomplex at 3.5 Angstroms resolution.
To Be Published
8VAF
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BU of 8vaf by Molmil
Cryogenic electron microscopy structure of apo human serum albumin
Descriptor: Serum albumin
Authors:Catalano, C, Lucier, K.W, To, D, Senko, S, Tran, N.L, Farwell, A.C, Silva, S.M, Dip, P.V, Poweleit, N, Scapin, G.
Deposit date:2023-12-11
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The CryoEM structure of human serum albumin in complex with ligands.
J.Struct.Biol., 216, 2024
8XEA
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BU of 8xea by Molmil
XBB.1.5 spike protein in complex with BD55-1205
Descriptor: BD55-1205 heavy chain, BD55-1205 light chain, Spike glycoprotein
Authors:Feng, L.L.
Deposit date:2023-12-11
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:XBB.1.5 spike protein in complex with BD55-1205
To Be Published

224004

数据于2024-08-21公开中

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