7UJL
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5O56
| Glycogen Phosphorylase b in complex with 29b | Descriptor: | (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... | Authors: | Solovou, T.G.A, Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. | Deposit date: | 2017-05-31 | Release date: | 2017-09-27 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
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8DMG
| CYP102A1 in Closed Conformation | Descriptor: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional cytochrome P450/NADPH--P450 reductase, FLAVIN MONONUCLEOTIDE, ... | Authors: | Su, M, Xu, H. | Deposit date: | 2022-07-08 | Release date: | 2023-07-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Insight into the conformational dynamics of cytochrome P450 CYP102A1 enzyme using Cryo-EM To Be Published
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8EFU
| a22L prion fibril | Descriptor: | Major prion protein | Authors: | Hoyt, F, Caughey, B. | Deposit date: | 2022-09-09 | Release date: | 2022-11-02 | Last modified: | 2022-11-23 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM of prion strains from the same genotype of host identifies conformational determinants. Plos Pathog., 18, 2022
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8BC3
| Cryo-EM Structure of a BmSF-TAL - Sulfofructose Schiff Base Complex | Descriptor: | (2~{R},3~{S},4~{S})-2,3,4,6-tetrakis(oxidanyl)hexane-1-sulfonic acid, BmSF-TAL | Authors: | Snow, A.J.D, Sharma, M, Blaza, J, Davies, G.J. | Deposit date: | 2022-10-14 | Release date: | 2023-01-18 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Structure and mechanism of sulfofructose transaldolase, a key enzyme in sulfoquinovose metabolism. Structure, 31, 2023
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8BC4
| Cryo-EM Structure of a BmSF-TAL - Sulfofructose Schiff Base Complex in symmetry group C1 | Descriptor: | (2~{R},3~{S},4~{S})-2,3,4,6-tetrakis(oxidanyl)hexane-1-sulfonic acid, Transaldolase | Authors: | Snow, A.J.D, Sharma, M, Blaza, J, Davies, G.J. | Deposit date: | 2022-10-14 | Release date: | 2023-01-18 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structure and mechanism of sulfofructose transaldolase, a key enzyme in sulfoquinovose metabolism. Structure, 31, 2023
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6JXW
| Complex of SUMO2 bound SLS4 from ICP0. | Descriptor: | SLS4-SIM from Ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier 2 | Authors: | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | Deposit date: | 2019-04-25 | Release date: | 2020-02-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6OTA
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6QXF
| Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | Descriptor: | CALCIUM ION, CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, ... | Authors: | Wilkinson, M, Drabavicius, G, Silanskas, A, Gasiunas, G, Siksnys, V, Wigley, D.B. | Deposit date: | 2019-03-07 | Release date: | 2019-05-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System. Mol.Cell, 75, 2019
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6QX3
| Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 | Descriptor: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... | Authors: | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | Deposit date: | 2019-03-07 | Release date: | 2019-09-04 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6DDE
| Mu Opioid Receptor-Gi Protein Complex | Descriptor: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. | Deposit date: | 2018-05-10 | Release date: | 2018-06-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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6R9G
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6D6A
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6R9V
| Crystal structure of Pediococcus acidilactici lactate oxidase A94G mutant | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, Putative L-lactate oxidase, ... | Authors: | Ashok, Y, Maksimainen, M.M, Lehtio, L. | Deposit date: | 2019-04-04 | Release date: | 2020-02-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | FMN-dependent oligomerization of putative lactate oxidase from Pediococcus acidilactici. Plos One, 15, 2020
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6RAZ
| D. melanogaster CMG-DNA, State 2B | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-18 | Last modified: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (4.46 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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8SCB
| Terminating ribosome with SRI-41315 | Descriptor: | (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... | Authors: | Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. | Deposit date: | 2023-04-05 | Release date: | 2023-12-27 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center. Nat.Chem.Biol., 20, 2024
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6RAW
| D. melanogaster CMG-DNA, State 1A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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6OQJ
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6RAX
| D. melanogaster CMG-DNA, State 1B | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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6DDF
| Mu Opioid Receptor-Gi Protein Complex | Descriptor: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Koehl, A, Hu, H, Maeda, S, Manglik, A, Kobilka, B.K, Skiniotis, G, Weis, W.I. | Deposit date: | 2018-05-10 | Release date: | 2018-06-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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6RAY
| D. melanogaster CMG-DNA, State 2A | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | Authors: | Eickhoff, P, Martino, F, Costa, A. | Deposit date: | 2019-04-08 | Release date: | 2019-09-11 | Last modified: | 2019-09-18 | Method: | ELECTRON MICROSCOPY (4.28 Å) | Cite: | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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6OQK
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6OWR
| NMR solution structure of YfiD | Descriptor: | Autonomous glycyl radical cofactor | Authors: | Bowman, S.E.J, Drennan, C.L. | Deposit date: | 2019-05-10 | Release date: | 2019-07-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. J.Biol.Inorg.Chem., 24, 2019
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8SQA
| The cryo-EM structure of the EcBAM/EspP(beta8-12) complex | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Autotransporter protein EspP translocator, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | Authors: | Wu, R, Noinaj, N. | Deposit date: | 2023-05-04 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | BAM orchestrates OMP biogenesis using a beta-templating mechanism To Be Published
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6RPV
| Extremely stable monomeric variant of human cystatin C with single amino acid substitution | Descriptor: | Cystatin-C | Authors: | Zhukov, I, Rodziewicz-Motowidlo, S, Maszota-Zieleniak, M, Jurczak, P, Kozak, M. | Deposit date: | 2019-05-14 | Release date: | 2019-07-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution. Febs J., 287, 2020
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