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6ZD1
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BU of 6zd1 by Molmil
Structure of apo telomerase from Candida Tropicalis
Descriptor: Telomerase reverse transcriptase
Authors:Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G.
Deposit date:2020-06-13
Release date:2021-04-28
Last modified:2021-05-12
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Nucleic Acids Res., 49, 2021
6ZDP
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BU of 6zdp by Molmil
Structure of telomerase from Candida Tropicalis in complexe with TWJ fragment of telomeric RNA
Descriptor: Chains: B, POTASSIUM ION, Telomerase reverse transcriptase
Authors:Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G.
Deposit date:2020-06-15
Release date:2021-04-28
Last modified:2021-05-12
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Nucleic Acids Res., 49, 2021
6ZD6
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BU of 6zd6 by Molmil
Structure of apo telomerase from Candida Tropicalis
Descriptor: Telomerase reverse transcriptase
Authors:Zhai, L, Rety, S, Chen, W.F, Auguin, D, Xi, X.G.
Deposit date:2020-06-13
Release date:2021-04-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structures of N-terminally truncated telomerase reverse transcriptase from fungi‡.
Nucleic Acids Res., 49, 2021
8JAH
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BU of 8jah by Molmil
Crystal structure of human CLEC12A C-type lectin domain
Descriptor: C-type lectin domain family 12 member A, POTASSIUM ION, SULFATE ION
Authors:Lei, Q, Tang, H, Dong, X.
Deposit date:2023-05-06
Release date:2024-03-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal.
J.Biol.Chem., 300, 2024
6BCX
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BU of 6bcx by Molmil
mTORC1 structure refined to 3.0 angstroms
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ...
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
6BCU
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BU of 6bcu by Molmil
Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ...
Authors:Pavletich, N.P, Yang, H.
Deposit date:2017-10-20
Release date:2017-12-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
4H1E
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BU of 4h1e by Molmil
Structure of BACE-1 Bound to (7aR)-6-benzoyl-7a-(4-(3-cyanophenyl)thiophen-2-yl)-3-methyl-4-oxohexahydro-1H-pyrrolo[3,4-d]pyrimidin-2(3H)-iminium
Descriptor: 3-{5-[(2E,4aR,7aR)-6-benzoyl-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile, Beta-secretase 1
Authors:Orth, P.
Deposit date:2012-09-10
Release date:2012-10-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation.
J.Med.Chem., 55, 2012
6AMR
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BU of 6amr by Molmil
Solution NMR structure of a putative thioredoxin (ECH_0218) in the reduced state from Ehrlichia chaffeensis, the etiological agent responsible for human monocytic ehrlichiosis. Seattle Structural Genomics Center for Infectious Disease target EhchA.00546.a
Descriptor: Thioredoxin
Authors:Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-11
Release date:2017-09-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR structures of oxidized and reduced Ehrlichia chaffeensis thioredoxin: NMR-invisible structure owing to backbone dynamics.
Acta Crystallogr F Struct Biol Commun, 74, 2018
1A6Z
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BU of 1a6z by Molmil
HFE (HUMAN) HEMOCHROMATOSIS PROTEIN
Descriptor: BETA-2-MICROGLOBULIN, HFE
Authors:Lebron, J.A, Bennett, M.J, Vaughn, D.E, Chirino, A.J, Snow, P.M, Mintier, G.A, Feder, J.N, Bjorkman, P.J.
Deposit date:1998-03-04
Release date:1999-03-23
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor.
Cell(Cambridge,Mass.), 93, 1998
2YC2
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BU of 2yc2 by Molmil
Intraflagellar Transport Complex 25-27 from Chlamydomonas
Descriptor: CALCIUM ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, SMALL RAB-RELATED GTPASE
Authors:Bhogaraju, S, Taschner, M, Lorentzen, E.
Deposit date:2011-03-11
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.588 Å)
Cite:Crystal Structure of the Intraflagellar Transport Complex 25/27.
Embo J., 30, 2011
6Z9W
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BU of 6z9w by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting LLGWVFAQV
Descriptor: Beta-2-microglobulin, LEU-LEU-GLY-TRP-VAL-PHE-ALA-GLN-VAL, MHC class I antigen
Authors:Rizkallah, P.J, Man, S, Redman, J.E.
Deposit date:2020-06-04
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
6Z9V
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BU of 6z9v by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting IIGWMWIPV
Descriptor: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
Authors:Rizkallah, P.J, Man, S, Redman, J.E.
Deposit date:2020-06-04
Release date:2021-06-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
6Z9X
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BU of 6z9x by Molmil
Human Class I Major Histocompatibility Complex, A02 allele, presenting LLS (t-butyl)Y FGTPT
Descriptor: Beta-2-microglobulin, LEU-LEU-SER-TUR-PHE-GLY-THR-PRO-THR, MHC class I antigen, ...
Authors:Rizkallah, P.J, Man, S, Redman, J.E.
Deposit date:2020-06-04
Release date:2021-06-30
Last modified:2024-07-10
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Synthetic Peptides with Inadvertent Chemical Modifications Can Activate Potentially Autoreactive T Cells.
J Immunol., 207, 2021
6Z1L
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BU of 6z1l by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.12
Descriptor: 1,2-ETHANEDIOL, BH32.12 protein, PHOSPHATE ION
Authors:Levy, C.W.
Deposit date:2020-05-13
Release date:2021-08-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
6Z1K
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BU of 6z1k by Molmil
A de novo Enzyme for the Morita-Baylis-Hillman Reaction BH32.6
Descriptor: 1,2-ETHANEDIOL, BH32.6 protein, CALCIUM ION, ...
Authors:Levy, C.W.
Deposit date:2020-05-13
Release date:2021-08-25
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Nat.Chem., 14, 2022
1DIY
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BU of 1diy by Molmil
CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARACHIDONIC ACID, ...
Authors:Malkowski, M.G, Ginell, S.L, Smith, W.L, Garavito, R.M.
Deposit date:1999-11-30
Release date:2000-09-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:The productive conformation of arachidonic acid bound to prostaglandin synthase.
Science, 289, 2000
2YC4
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BU of 2yc4 by Molmil
Intraflagellar Transport Complex 25-27 from Chlamydomonas
Descriptor: CALCIUM ION, CHLORIDE ION, INTRAFLAGELLAR TRANSPORT PROTEIN 25, ...
Authors:Bhogaraju, S, Taschner, M, Lorentzen, E.
Deposit date:2011-03-11
Release date:2011-03-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Intraflagellar Transport Complex 25/27.
Embo J., 30, 2011
8JRB
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BU of 8jrb by Molmil
Structure of DNA polymerase 1 from Aquifex pyrophilus
Descriptor: DNA polymerase I
Authors:Clement, P, Nair, D.T.
Deposit date:2023-06-16
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A conserved polar residue plays a critical role in mismatch detection in A-family DNA polymerases.
Int.J.Biol.Macromol., 269, 2024
6ZYZ
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BU of 6zyz by Molmil
Structure of the borneol dehydrogenases of Salvia rosmarinus with NAD+
Descriptor: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Borneol dehydrogenase from salvia rosmarinus, CHLORIDE ION, ...
Authors:Dimos, N, Helmer, C.P.O, Loll, B.
Deposit date:2020-08-03
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:A Structural View on the Stereospecificity of Plant Borneol-Type Dehydrogenases.
Chemcatchem, 13, 2021
1O7I
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BU of 1o7i by Molmil
Crystal structure of a single stranded DNA binding protein
Descriptor: SINGLE STRANDED DNA BINDING PROTEIN, SULFATE ION
Authors:Kerr, I.D, Naismith, J.H.
Deposit date:2002-11-05
Release date:2003-06-25
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Insights into ssDNA recognition by the OB fold from a structural and thermodynamic study of Sulfolobus SSB protein.
EMBO J., 22, 2003
8JWY
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BU of 8jwy by Molmil
Crystal structure of A2AR-T4L in complex with 2-118
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ...
Authors:Weng, Y, Chen, Y, Xu, Y, Song, G.
Deposit date:2023-06-29
Release date:2023-08-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
6ZZT
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BU of 6zzt by Molmil
Structure of the borneol dehydrogenases of Salvia rosmarinus (high salt condition)
Descriptor: BORNEOL DEHYDROGENASE, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Dimos, N, Helmer, C.P.O, Loll, B.
Deposit date:2020-08-05
Release date:2021-02-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A Structural View on the Stereospecificity of Plant Borneol-Type Dehydrogenases.
Chemcatchem, 13, 2021
8JWZ
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BU of 8jwz by Molmil
Crystal structure of A2AR-T4L in complex with AB928
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]-1,2,3-triazol-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ...
Authors:Weng, Y, Chen, Y, Xu, Y, Song, G.
Deposit date:2023-06-29
Release date:2023-08-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.
Sci China Life Sci, 67, 2024
7WTQ
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BU of 7wtq by Molmil
Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Tsr1-2 (without Rps2)
Descriptor: 18S rRNA, 18S rRNA (guanine(1575)-N(7))-methyltransferase, 40S ribosomal protein S1-A, ...
Authors:Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R.
Deposit date:2022-02-05
Release date:2022-10-19
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Nucleic Acids Res., 50, 2022
8TE0
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BU of 8te0 by Molmil
16mer self-complementary duplex RNA with D:C pair sequence 1
Descriptor: MAGNESIUM ION, RNA
Authors:Fang, Z, Jia, X, Szostak, J.W.
Deposit date:2023-07-05
Release date:2024-06-12
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024

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数据于2024-10-16公开中

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