6T23
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![BU of 6t23 by Molmil](/molmil-images/mine/6t23) | Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Pospich, S, Merino, F, Raunser, S. | Deposit date: | 2019-10-07 | Release date: | 2020-03-04 | Last modified: | 2020-04-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure, 28, 2020
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8OH4
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![BU of 8oh4 by Molmil](/molmil-images/mine/8oh4) | |
6T24
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![BU of 6t24 by Molmil](/molmil-images/mine/6t24) | Cryo-EM structure of jasplakinolide-stabilized F-actin (aged) | Descriptor: | (4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | Authors: | Pospich, S, Merino, F, Raunser, S. | Deposit date: | 2019-10-07 | Release date: | 2020-03-04 | Last modified: | 2020-04-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure, 28, 2020
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6DED
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![BU of 6ded by Molmil](/molmil-images/mine/6ded) | |
6U96
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![BU of 6u96 by Molmil](/molmil-images/mine/6u96) | Actin phalloidin at BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Das, S, Ge, P, Durer, Z.A.O, Grintsevich, E.E, Zhou, Z.H, Reisler, E. | Deposit date: | 2019-09-06 | Release date: | 2020-05-13 | Last modified: | 2020-05-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | D-loop Dynamics and Near-Atomic-Resolution Cryo-EM Structure of Phalloidin-Bound F-Actin. Structure, 28, 2020
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3LUE
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![BU of 3lue by Molmil](/molmil-images/mine/3lue) | Model of alpha-actinin CH1 bound to F-actin | Descriptor: | Actin, cytoplasmic 1, Alpha-actinin-3 | Authors: | Galkin, V.E, Orlova, A, Salmazo, A, Djinovic-Carugo, K, Egelman, E.H. | Deposit date: | 2010-02-17 | Release date: | 2010-04-28 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Opening of tandem calponin homology domains regulates their affinity for F-actin. Nat.Struct.Mol.Biol., 17, 2010
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3MFP
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![BU of 3mfp by Molmil](/molmil-images/mine/3mfp) | Atomic model of F-actin based on a 6.6 angstrom resolution cryoEM map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | Authors: | Fujii, T, Iwane, A.H, Yanagida, T, Namba, K. | Deposit date: | 2010-04-03 | Release date: | 2010-09-29 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Direct visualization of secondary structures of F-actin by electron cryomicroscopy Nature, 467, 2010
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6IUG
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![BU of 6iug by Molmil](/molmil-images/mine/6iug) | Cryo-EM structure of the plant actin filaments from Zea mays pollen | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, pollen F-actin | Authors: | Ren, Z.H, Zhang, Y, Zhang, Y, He, Y.Q, Du, P.Z, Wang, Z.X, Sun, F, Ren, H.Y. | Deposit date: | 2018-11-28 | Release date: | 2019-11-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM Structure of Actin Filaments fromZea maysPollen. Plant Cell, 31, 2019
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3J8I
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![BU of 3j8i by Molmil](/molmil-images/mine/3j8i) | Near-Atomic Resolution for One State of F-Actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Galkin, V.E. | Deposit date: | 2014-11-06 | Release date: | 2015-01-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Near-atomic resolution for one state of f-actin. Structure, 23, 2015
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3M3N
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![BU of 3m3n by Molmil](/molmil-images/mine/3m3n) | Structure of a Longitudinal Actin Dimer Assembled by Tandem W Domains | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Rebowski, G, Namgoong, S, Dominguez, R. | Deposit date: | 2010-03-09 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (7 Å) | Cite: | Structure of a longitudinal actin dimer assembled by tandem w domains: implications for actin filament nucleation. J.Mol.Biol., 403, 2010
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3M1F
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![BU of 3m1f by Molmil](/molmil-images/mine/3m1f) | |
3M6G
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![BU of 3m6g by Molmil](/molmil-images/mine/3m6g) | Crystal structure of actin in complex with lobophorolide | Descriptor: | (1S,3S,4S,5S,7R,8S,9R,12E,14E,16R,17R,19R)-16-hydroxy-9-{(1S,2S,3S)-2-hydroxy-5-[(2S,4R,6S)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl]-1,3-dimethylpentyl}-3,5,7,17-tetramethoxy-8,14-dimethyl-11H-spiro[10,23-dioxabicyclo[17.3.1]tricosa-12,14,20-triene-4,2'-oxiran]-11-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Allingham, J.S. | Deposit date: | 2010-03-15 | Release date: | 2010-09-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two molecules of lobophorolide cooperate to stabilize an actin dimer using both their "ring" and "tail" region. Chem.Biol., 17, 2010
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6ICT
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![BU of 6ict by Molmil](/molmil-images/mine/6ict) | Structure of SETD3 bound to SAH and methylated actin | Descriptor: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | Authors: | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | Deposit date: | 2018-09-07 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.952 Å) | Cite: | Structural insights into SETD3-mediated histidine methylation on beta-actin. Elife, 8, 2019
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8DMX
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![BU of 8dmx by Molmil](/molmil-images/mine/8dmx) | Cryo-EM structure of skeletal muscle alpha-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-08 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
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8DNH
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![BU of 8dnh by Molmil](/molmil-images/mine/8dnh) | Cryo-EM structure of nonmuscle beta-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-11 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
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1C0F
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![BU of 1c0f by Molmil](/molmil-images/mine/1c0f) | CRYSTAL STRUCTURE OF DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1 | Descriptor: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-07-16 | Release date: | 2000-03-01 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras J.Mol.Biol., 296, 2000
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8DMY
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![BU of 8dmy by Molmil](/molmil-images/mine/8dmy) | Cryo-EM structure of cardiac muscle alpha-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-09 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
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8DNF
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![BU of 8dnf by Molmil](/molmil-images/mine/8dnf) | Cryo-EM structure of nonmuscle gamma-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ... | Authors: | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | Deposit date: | 2022-07-11 | Release date: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural insights into actin isoforms. Elife, 12, 2023
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1ATN
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![BU of 1atn by Molmil](/molmil-images/mine/1atn) | Atomic structure of the actin:DNASE I complex | Descriptor: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Kabsch, W, Mannherz, H.G, Suck, D, Pai, E, Holmes, K.C. | Deposit date: | 1991-03-08 | Release date: | 1992-07-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Atomic structure of the actin:DNase I complex. Nature, 347, 1990
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1H1V
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![BU of 1h1v by Molmil](/molmil-images/mine/1h1v) | gelsolin G4-G6/actin complex | Descriptor: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Choe, H, Burtnick, L.D, Mejillano, M, Yin, H.L, Robinson, R.C, Choe, S. | Deposit date: | 2002-07-23 | Release date: | 2003-01-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The Calcium Activation of Gelsolin:Insights from the 3A Structure of the G4-G6/Actin Complex J.Mol.Biol., 324, 2002
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1IJJ
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![BU of 1ijj by Molmil](/molmil-images/mine/1ijj) | THE X-RAY CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN RABBIT SKELETAL MUSCLE ACTIN AND LATRUNCULIN A AT 2.85 A RESOLUTION | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Vorobiev, S.M, Bubb, M.R, Almo, S.C. | Deposit date: | 2001-04-26 | Release date: | 2002-04-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution J.Biol.Chem., 277, 2002
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1J6Z
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![BU of 1j6z by Molmil](/molmil-images/mine/1j6z) | UNCOMPLEXED ACTIN | Descriptor: | ACTIN ALPHA 1, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Otterbein, L.R, Graceffa, P, Dominguez, R. | Deposit date: | 2001-05-15 | Release date: | 2001-08-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | The crystal structure of uncomplexed actin in the ADP state. Science, 293, 2001
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3AAA
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![BU of 3aaa by Molmil](/molmil-images/mine/3aaa) | Crystal Structure of Actin capping protein in complex with V-1 | Descriptor: | F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, ISOPROPYL ALCOHOL, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-12 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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1CJA
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![BU of 1cja by Molmil](/molmil-images/mine/1cja) | ACTIN-FRAGMIN KINASE, CATALYTIC DOMAIN FROM PHYSARUM POLYCEPHALUM | Descriptor: | ADENOSINE MONOPHOSPHATE, PROTEIN (ACTIN-FRAGMIN KINASE) | Authors: | Steinbacher, S, Hof, P, Eichinger, L, Schleicher, M, Gettemans, J, Vandekerckhove, J, Huber, R, Benz, J. | Deposit date: | 1999-04-08 | Release date: | 1999-06-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structure of the Physarum polycephalum actin-fragmin kinase: an atypical protein kinase with a specialized substrate-binding domain. EMBO J., 18, 1999
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3CJB
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![BU of 3cjb by Molmil](/molmil-images/mine/3cjb) | Actin dimer cross-linked by V. cholerae MARTX toxin and complexed with Gelsolin-segment 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Sawaya, M.R, Kudryashov, D.S, Pashkov, I, Reisler, E, Yeates, T.O. | Deposit date: | 2008-03-12 | Release date: | 2008-03-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin. Proc.Natl.Acad.Sci.USA, 105, 2008
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