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4UT6
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Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 B7, ...
Authors:Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UTA
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Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8
Descriptor: BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 HEAVY CHAIN, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C8 LIGHT CHAIN, ENVELOPE GLYCOPROTEIN E, ...
Authors:Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4UT9
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Crystal structure of dengue 2 virus envelope glycoprotein dimer in complex with the ScFv fragment of the broadly neutralizing human antibody EDE1 C10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE1 C10, ENVELOPE GLYCOPROTEIN E
Authors:Rouvinski, A, Guardado-Calvo, P, Barba-Spaeth, G, Duquerroy, S, Vaney, M.C, Rey, F.A.
Deposit date:2014-07-18
Release date:2015-01-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Recognition Determinants of Broadly Neutralizing Human Antibodies Against Dengue Viruses.
Nature, 520, 2015
4V8U
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BU of 4v8u by Molmil
Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex.
Descriptor: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, Y.G, Feng, S, Chen, Y.
Deposit date:2012-08-28
Release date:2014-07-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex.
PLoS ONE, 8, 2013
4UHJ
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Crystal structure of the receiver domain of CpxR from E. coli (orthorhombic form)
Descriptor: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
Authors:Mechaly, A.E, Alzari, P.M.A.
Deposit date:2015-03-24
Release date:2016-04-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
Structure, 25, 2017
4UHS
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Crystal structure of the receiver domain of CpxR from E. coli (tetragonal form)
Descriptor: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
Authors:Mechaly, A.E, Alzari, P.M.A.
Deposit date:2015-03-25
Release date:2016-04-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (5 Å)
Cite:Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance.
J. Struct. Biol., 204, 2018
4UHK
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BU of 4uhk by Molmil
Crystal structure of the receiver domain of CpxR from E. coli (phosphorylated)
Descriptor: MAGNESIUM ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
Authors:Mechaly, A.E, Alzari, P.M.A.
Deposit date:2015-03-24
Release date:2016-04-13
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
Structure, 25, 2017
4UF0
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BU of 4uf0 by Molmil
Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.
Descriptor: 1,2-ETHANEDIOL, 2-{[(2-{[(E)-2-(dimethylamino)ethenyl](ethyl)amino}-2-oxoethyl)amino]methyl}pyridine-4-carboxylic acid, FE (II) ION, ...
Authors:Srikannathasan, V, Johansson, C, Gileadi, C, Tobias, K, Kopec, J, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.
Deposit date:2014-12-22
Release date:2015-01-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
4UHT
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BU of 4uht by Molmil
Crystal structure of the DNA binding domain of CpxR from E. coli
Descriptor: CHLORIDE ION, TRANSCRIPTIONAL REGULATORY PROTEIN CPXR
Authors:Mechaly, A.E, Alzari, P.M.A.
Deposit date:2015-03-25
Release date:2016-04-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance.
J. Struct. Biol., 204, 2018
4V48
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Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the initiation-like state of E. coli 70S ribosome
Descriptor: 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ...
Authors:Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J.
Deposit date:2003-05-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Study of the structural dynamics of the E. coli 70S ribosome using real space refinement
Cell(Cambridge,Mass.), 113, 2003
6Q69
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Crystal structure of porcine ACBD3 GOLD domain in complex with 3A protein of enterovirus-G1
Descriptor: Genome polyprotein, Peripherial benzodiazepine receptor associated protein
Authors:Smola, M, Boura, E, Klima, M.
Deposit date:2018-12-10
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.747 Å)
Cite:Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses.
Arch. Virol., 165, 2020
4UM4
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BU of 4um4 by Molmil
STRUCTURE OF INORGANIC PYROPHOSPHATASE FROM ESCHERICHIA COLI IN COMPLEX WITH SULFATE
Descriptor: INORGANIC PYROPHOSPHATASE, SULFATE ION
Authors:Campos-Acevedo, A.A, Rudino-Pinera, E.
Deposit date:2014-05-15
Release date:2014-11-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:First attempts to crystallize a non-homogeneous sample of thioredoxin from Litopenaeus vannamei: What to do when you have diffraction data of a protein that is not the target?
Biochem Biophys Rep, 8, 2016
6Q67
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BU of 6q67 by Molmil
Crystal structure of porcine ACBD3 GOLD domain in complex with 3A protein of Aichivirus C
Descriptor: 3A, Peripherial benzodiazepine receptor associated protein, beta-D-glucopyranose
Authors:Smola, M, Boura, E, Klima, M.
Deposit date:2018-12-10
Release date:2019-11-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses.
Arch. Virol., 165, 2020
4U32
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BU of 4u32 by Molmil
Human mesotrypsin complexed with HAI-2 Kunitz domain 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Kunitz-type protease inhibitor 2, ...
Authors:Wang, R, Soares, A.S, Radisky, E.S.
Deposit date:2014-07-18
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN.
J.Biol.Chem., 289, 2014
4U30
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BU of 4u30 by Molmil
Human mesotrypsin complexed with bikunin Kunitz domain 2
Descriptor: CALCIUM ION, Trypsin-3, Trypstatin
Authors:Wang, R, Soares, A.S, Radisky, E.S.
Deposit date:2014-07-18
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Sequence and Conformational Specificity in Substrate Recognition: SEVERAL HUMAN KUNITZ PROTEASE INHIBITOR DOMAINS ARE SPECIFIC SUBSTRATES OF MESOTRYPSIN.
J.Biol.Chem., 289, 2014
4UMC
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BU of 4umc by Molmil
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Descriptor: L-PHOSPHOLACTATE, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J.
Deposit date:2014-05-16
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.
Bioorg.Chem., 57, 2014
4UMB
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BU of 4umb by Molmil
Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water
Descriptor: (2R)-2-(phosphonooxy)propanoic acid, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J.
Deposit date:2014-05-16
Release date:2014-10-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water.
Bioorg.Chem., 57, 2014
4V8M
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BU of 4v8m by Molmil
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
Descriptor: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ...
Authors:Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J.
Deposit date:2012-12-09
Release date:2014-07-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.57 Å)
Cite:High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Nature, 494, 2013
4V7J
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BU of 4v7j by Molmil
Structure of RelE nuclease bound to the 70S ribosome (precleavage state)
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
Deposit date:2009-11-02
Release date:2014-07-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
6JDW
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BU of 6jdw by Molmil
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GAMMA-AMINO BUTYRIC ACID
Descriptor: GAMMA-AMINO-BUTANOIC ACID, PROTEIN (L-ARGININE:GLYCINE AMIDINOTRANSFERASE)
Authors:Fritsche, E, Humm, A, Huber, R.
Deposit date:1998-10-12
Release date:1999-02-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
J.Biol.Chem., 274, 1999
4V14
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Structure and function analysis of MutT from the psychrofile fish pathogen Aliivibrio salmonicida and the mesophile Vibrio cholerae
Descriptor: MUTATOR MUTT PROTEIN
Authors:Lian, K, Leiros, H.-K.S, Moe, E.
Deposit date:2014-09-24
Release date:2015-02-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mutt from the Fish Pathogen Aliivibrio Salmonicida is a Cold-Active Nucleotide-Pool Sanitization Enzyme with Unexpectedly High Thermostability.
FEBS Open Bio, 5, 2015
4UDS
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BU of 4uds by Molmil
Crystal structure of MbdR regulator from Azoarcus sp. CIB
Descriptor: MBDR REGULATOR
Authors:Liu, H, Liu, H.X, MacMahon, S.A, Juarez, J.F, Zamarro, M.T, Eberlein, C, Boll, M, Carmona, M, Diaz, E, Naismith, J.H.
Deposit date:2014-12-11
Release date:2014-12-24
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Unraveling the Specific Regulation of the Mbd Central Pathway for the Anaerobic Degradation of 3-Methylbenzoate.
J.Biol.Chem., 290, 2015
1E1X
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BU of 1e1x by Molmil
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR NU6027
Descriptor: 6-CYCLOHEXYLMETHYLOXY-5-NITROSO-PYRIMIDINE-2,4-DIAMINE, CYCLIN-DEPENDENT PROTEIN KINASE 2
Authors:Endicott, J.A, Noble, M.E.M, Johnson, L.N.
Deposit date:2000-05-11
Release date:2001-05-10
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Identification of Novel Purine and Pyrimidine Cyclin-Dependent Kinase Inhibitors with Distinct Molecular Interactions and Tumor Cell Growth Inhibition Profiles.
J.Med.Chem., 43, 2000
1DTQ
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-1 (PETT131A94)
Descriptor: HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-NITRILOMETHYL-PYRIDYL]-THIOUREA
Authors:Ren, J, Diprose, J, Warren, J, Esnouf, R.M, Bird, L.E, Ikemizu, S, Slater, M, Milton, J, Balzarini, J, Stuart, D.I, Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-03-20
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1DTT
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BU of 1dtt by Molmil
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)
Descriptor: HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA
Authors:Ren, J, Diprose, J, Warren, J, Esnouf, R.M, Bird, L.E, Ikemizu, S, Slater, M, Milton, J, Balzarini, J, Stuart, D.I, Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-04-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000

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