PDB: 79225 resultsInfo pagesStatus searchChemie searchBIRD

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4P1Z	Structure of the MID domain from MIWI Descriptor: Piwi-like protein 1 Authors: Cora, E, McCarthy, A.A, Pillai, R.S. Deposit date: 2014-02-28 Release date: 2014-05-07 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The MID-PIWI module of Piwi proteins specifies nucleotide- and strand-biases of piRNAs. Rna, 20, 2014
5F9Y	Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Proline and AMP Descriptor: ADENOSINE MONOPHOSPHATE, Aminoacyl-tRNA synthetase, PHOSPHATE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-12-10 Release date: 2016-11-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Proline and AMP to be published
8TC8	Human asparaginyl-tRNA synthetase bound to adenosine 5'-sulfamate Descriptor: 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, Asparagine--tRNA ligase, cytoplasmic, ... Authors: Dogovski, C, Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W. Deposit date: 2023-06-30 Release date: 2024-02-07 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase. Nat Commun, 15, 2024
5F9Z	Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with Halofuginone and AMPPNP Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Aminoacyl-tRNA synthetase, GLYCEROL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-12-10 Release date: 2016-11-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of Prolyl-tRNA Synthetase from Cryptosporidium parvum complexed with Halofuginone and AMPPNP to be published
6C86	Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine Descriptor: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2018-01-24 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-Lysylsulfamoyl Adenosine to be published
7X09	Homo sapiens Prolyl-tRNA Synthetase (HsPRS) in Complex with inhibitors L95 and Halofuginone Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, BROMIDE ION, Bifunctional glutamate/proline--tRNA ligase, ... Authors: Manickam, Y, Babbar, P, Pillai, P, Sharma, A. Deposit date: 2022-02-21 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of Homo sapiens Prolyl-tRNA synthetase (HsPRS) with double inhibitors (HF and L95) To Be Published
7X1O	Homo sapiens Prolyl-tRNA Synthetase (HsPRS) in Complex with double inhibitors HF and L95 Descriptor: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, BROMIDE ION, Bifunctional glutamate/proline--tRNA ligase, ... Authors: Manickam, Y, Babbar, P, Sharma, A. Deposit date: 2022-02-24 Release date: 2023-08-30 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Crystal structure of Homo sapiens Prolyl-tRNA synthetase (HsPRS) with double inhibitors (HF and L95) To Be Published
8T5N	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-06-14 Release date: 2023-06-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound) To be published
4YCU	Crystal structure of cladosporin in complex with human lysyl-tRNA synthetase Descriptor: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, GLYCEROL, LYSINE, ... Authors: Fang, P, Wang, J, Guo, M. Deposit date: 2015-02-20 Release date: 2015-06-10 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural Basis for Specific Inhibition of tRNA Synthetase by an ATP Competitive Inhibitor. Chem. Biol., 22, 2015
6HHW	Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine Descriptor: 5'-O-(N-(L-aspartyl)-sulfamoyl)uridine, Aspartate--tRNA(Asp) ligase Authors: De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. Deposit date: 2018-08-29 Release date: 2019-12-18 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
8U2P	Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-O-(glycylsulfamoyl)adenosine, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Last modified: 2024-04-10 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (G5A bound) To be published
2TOB	SOLUTION STRUCTURE OF THE TOBRAMYCIN-RNA APTAMER COMPLEX, NMR, 13 STRUCTURES Descriptor: 1,3-DIAMINO-4,5,6-TRIHYDROXY-CYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ... Authors: Jiang, L, Patel, D.J. Deposit date: 1998-06-17 Release date: 1999-06-22 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure of the tobramycin-RNA aptamer complex. Nat.Struct.Biol., 5, 1998
3AXZ	Crystal structure of Haemophilus influenzae TrmD in complex with adenosine Descriptor: ADENOSINE, tRNA (guanine-N(1)-)-methyltransferase Authors: Yoshida, K, Goto-Ito, S, Ito, T, Hou, Y.M, Yokoyama, S. Deposit date: 2011-04-21 Release date: 2011-08-17 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Differentiating analogous tRNA methyltransferases by fragments of the methyl donor. Rna, 17, 2011
8RIS	Computationally redesigend variant of Pyrrolysyl-tRNA Synthetase (Y306A) Descriptor: 1,2-ETHANEDIOL, GLYCEROL, PENTAETHYLENE GLYCOL, ... Authors: Oberdorfer, G, Moser, M, Stoll, D. Deposit date: 2023-12-19 Release date: 2025-01-01 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Computationally redesigend variant of Pyrrolysyl-tRNA Synthetase (Y306A) To Be Published
7V8K	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-08-23 Release date: 2022-09-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with L-Proline To Be Published
7V8J	Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate Descriptor: 1,2-ETHANEDIOL, 5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, PROLINE, ... Authors: Manickam, Y, Malhotra, N, Sharma, A. Deposit date: 2021-08-23 Release date: 2022-09-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.519 Å) Cite: Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with the reaction intermediates proline-adenylate (Pro-AMP) and pyrophosphate To Be Published
4XKZ	Crystal structure of the C-terminal anticodon loop binding domain of a valyl-tRNA synthetase from Pseudomonas aeruginosa Descriptor: IODIDE ION, TRIETHYLENE GLYCOL, Valine-tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2015-01-12 Release date: 2015-02-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the C-terminal anticodon loop binding domain of a valyl-tRNA synthetase from Pseudomonas aeruginosa. To Be Published
8U2Q	Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) Descriptor: 1,2-ETHANEDIOL, 5'-O-(glycylsulfamoyl)adenosine, CHLORIDE ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2023-09-06 Release date: 2023-09-13 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal Structure of Glycine--tRNA ligase active site chimera from Mycobacterium thermoresistibile/tuberculosis (G5A bound) To be published
6SJC	Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine Descriptor: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase Authors: De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. Deposit date: 2019-08-13 Release date: 2020-01-08 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
5TGT	Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa Descriptor: GLYCEROL, Glutamate--tRNA ligase, NONAETHYLENE GLYCOL, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-09-28 Release date: 2016-10-12 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structure of glytamyl-tRNA synthetase GluRS from Pseudomonas aeruginosa To Be Published
6AQH	Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium thermoresistibile complexed with L-lysine and Cladosporin Descriptor: 1,2-ETHANEDIOL, LYSINE, Lysine--tRNA ligase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-08-19 Release date: 2017-08-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Crystal Structure of Lysyl-tRNA Synthetase from Mycobacterium thermoresistibile complexed with L-lysine and Cladosporin to be published
484D	SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX Descriptor: BASIC REV PEPTIDE, RNA APTAMER Authors: Ye, X, Gorin, A.A, Frederick, R, Hu, W, Majumdar, A, Xu, W, Mclendon, G, Ellington, A, Patel, D.J. Deposit date: 1999-08-02 Release date: 1999-10-14 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: RNA architecture dictates the conformations of a bound peptide. Chem.Biol., 6, 1999
6BLJ	Crystal structure of cytoplasmic Serine-tRNA ligase from Naegleria fowleri in complex with AMP Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Serine-tRNA ligase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2017-11-10 Release date: 2017-12-20 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of cytoplasmic Serine-tRNA ligase from Neisseria fowlerii in complex with AMP TO BE PUBLISHED
1YID	Crystal structure of tryptophanyl tRNA synthetase II from Deinococcus radiodurans in complex with ATP. Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, tryptophanyl-tRNA synthetase Authors: Buddha, M.R, Crane, B.R. Deposit date: 2005-01-11 Release date: 2005-08-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structures of tryptophanyl-tRNA synthetase II from Deinococcus radiodurans bound to ATP and tryptophan. Insight into subunit cooperativity and domain motions linked to catalysis J.Biol.Chem., 280, 2005
259D	RNA HYDRATION: A DETAILED LOOK Descriptor: RNA (5'-R(*CP*CP*CP*CP*GP*GP*GP*G)-3') Authors: Egli, M, Portmann, S, Usman, N. Deposit date: 1996-05-03 Release date: 1996-08-26 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.46 Å) Cite: RNA hydration: a detailed look. Biochemistry, 35, 1996

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