PDB: 2262 resultsInfo pagesStatus searchChemie searchBIRD

---

2ZCJ	Ternary structure of the Glu119Gln M.HhaI, C5-Cytosine DNA methyltransferase, with unmodified DNA and AdoHcy Descriptor: DNA (5'-D(*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DGP*DAP*DTP*DAP*DGP*DCP*DGP*DCP*DTP*DAP*DTP*DC)-3'), Modification methylase HhaI, ... Authors: Shieh, F.K, Reich, N.O. Deposit date: 2007-11-09 Release date: 2007-12-04 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: AdoMet-dependent Methyl-transfer: Glu(119) Is Essential for DNA C5-Cytosine Methyltransferase M.HhaI J.Mol.Biol., 373, 2007
6LQP	Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S1-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
4V6U	Promiscuous behavior of proteins in archaeal ribosomes revealed by cryo-EM: implications for evolution of eukaryotic ribosomes Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10P, ... Authors: Armache, J.-P, Anger, A.M, Marquez, V, Frankenberg, S, Froehlich, T, Villa, E, Berninghausen, O, Thomm, M, Arnold, G.J, Beckmann, R, Wilson, D.N. Deposit date: 2012-08-09 Release date: 2014-07-09 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution. Nucleic Acids Res., 41, 2013
4V6X	Structure of the human 80S ribosome Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. Deposit date: 2013-02-27 Release date: 2014-07-09 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (5 Å) Cite: Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
9B8M	Crystal structure of ornithine decarboxylase in complex with a novel inhibitor Descriptor: O-{[(3R)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE Authors: Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S. Deposit date: 2024-03-31 Release date: 2025-03-12 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors. J.Med.Chem., 68, 2025
9B8N	Crystal structure of ornithine decarboxylase in complex with a novel inhibitor (10-S) Descriptor: O-{[(3S)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE Authors: Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S. Deposit date: 2024-03-31 Release date: 2025-03-12 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2 Å) Cite: Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors. J.Med.Chem., 68, 2025
3ZCX	Structure of GAPDH from Thermosynechococcus elongatus Descriptor: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Cotton, C.A.R, Murray, J.W. Deposit date: 2012-11-23 Release date: 2013-12-11 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Structure of Gapdh To be Published
6LQU	Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S pre-rRNA, 40S ribosomal protein S11-A, ... Authors: Du, Y, Ye, K. Deposit date: 2020-01-14 Release date: 2020-09-16 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states. Science, 369, 2020
6P5N	Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ... Authors: Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. Deposit date: 2019-05-30 Release date: 2019-09-25 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
3X2S	Crystal structure of pyrene-conjugated adenylate kinase Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Fujii, A, Sekiguchi, Y, Matsumura, H, Inoue, T, Chung, W.-S, Hirota, S, Matsuo, T. Deposit date: 2014-12-31 Release date: 2015-04-01 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Excimer Emission Properties on Pyrene-Labeled Protein Surface: Correlation between Emission Spectra, Ring Stacking Modes, and Flexibilities of Pyrene Probes. Bioconjug.Chem., 26, 2015
4V8Y	Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex Descriptor: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... Authors: Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. Deposit date: 2013-07-20 Release date: 2014-07-09 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (4.3 Å) Cite: Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
4V4N	Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... Authors: Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. Deposit date: 2013-06-17 Release date: 2014-07-09 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (9 Å) Cite: Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
9BUP	Single particle CryoEM structure of the Pf80S ribosome in non-rotated PRE state (nrt A-P-E) Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... Authors: Anton, L, Haile, M, Ho, C.M. Deposit date: 2024-05-17 Release date: 2025-05-28 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis To be published
4QBG	Crystal structure of a stable adenylate kinase variant AKlse4 Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Moon, S, Bae, E. Deposit date: 2014-05-08 Release date: 2014-06-25 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases. Proteins, 82, 2014
1QBB	BACTERIAL CHITOBIASE COMPLEXED WITH CHITOBIOSE (DINAG) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHITOBIASE, SULFATE ION Authors: Tews, I, Perrakis, A, Oppenheim, A, Dauter, Z, Wilson, K.S, Vorgias, C.E. Deposit date: 1996-06-07 Release date: 1997-02-12 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease. Nat.Struct.Biol., 3, 1996
1QBA	BACTERIAL CHITOBIASE, GLYCOSYL HYDROLASE FAMILY 20 Descriptor: CHITOBIASE, SULFATE ION Authors: Tews, I, Perrakis, A, Oppenheim, A, Dauter, Z, Wilson, K.S, Vorgias, C.E. Deposit date: 1996-06-06 Release date: 1997-01-11 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease. Nat.Struct.Biol., 3, 1996
1QF9	PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG IN UMP/CMP KINASE Descriptor: ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Schlichting, I, Reinstein, J. Deposit date: 1999-04-07 Release date: 1999-08-16 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog. Nat.Struct.Biol., 6, 1999
6P5K	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ... Authors: Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. Deposit date: 2019-05-30 Release date: 2019-09-18 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
4QBH	Crystal structure of a stable adenylate kinase variant AKlse5 Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... Authors: Moon, S, Bae, E. Deposit date: 2014-05-08 Release date: 2014-06-25 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Effectiveness and limitations of local structural entropy optimization in the thermal stabilization of mesophilic and thermophilic adenylate kinases. Proteins, 82, 2014
7QEP	Cryo-EM structure of the ribosome from Encephalitozoon cuniculi Descriptor: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... Authors: Nicholson, D, Ranson, N.A, Melnikov, S.V. Deposit date: 2021-12-03 Release date: 2022-02-09 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Adaptation to genome decay in the structure of the smallest eukaryotic ribosome Nat Commun, 13, 2022
9C8K	Rabbit Hemorrhagic Disease Virus reinitiation stimulating TURBS RNA bound to rabbit ribosome Descriptor: 18S ribosomal RNA, 40S ribosomal protein S26, 40S ribosomal protein eS19, ... Authors: Sherlock, M.E, Kieft, J.S. Deposit date: 2024-06-12 Release date: 2025-02-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: A conserved class of viral RNA structures regulates translation reinitiation through dynamic ribosome interactions. Cell Rep, 44, 2025
3A28	Crystal structure of L-2,3-butanediol dehydrogenase Descriptor: BETA-MERCAPTOETHANOL, L-2.3-butanediol dehydrogenase, MAGNESIUM ION, ... Authors: Otagiri, M, Kurisu, G, Ui, S, Kusunoki, M. Deposit date: 2009-05-02 Release date: 2009-12-15 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural basis for chiral substrate recognition by two 2,3-butanediol dehydrogenases Febs Lett., 584, 2010
6MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET Descriptor: CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), ... Authors: Cheng, X. Deposit date: 1998-08-05 Release date: 1998-08-12 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.05 Å) Cite: DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase. Nucleic Acids Res., 25, 1997
5NDG	Crystal structure of geneticin (G418) bound to the yeast 80S ribosome Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... Authors: Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. Deposit date: 2017-03-08 Release date: 2017-12-13 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6UZ7	K.lactis 80S ribosome with p/PE tRNA and eIF5B Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... Authors: Fernandez, I.S, Huang, B.Y. Deposit date: 2019-11-14 Release date: 2020-01-15 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation. Proc.Natl.Acad.Sci.USA, 117, 2020

<61626364656667686970717273747576>