6RWL
| SIVrcm intasome | Descriptor: | DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3'), DNA (5'-D(P*GP*CP*TP*AP*AP*GP*AP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*CP*CP*A)-3'), Pol protein, ... | Authors: | Cherepanov, P, Nans, A, Cook, N. | Deposit date: | 2019-06-05 | Release date: | 2020-02-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural basis of second-generation HIV integrase inhibitor action and viral resistance. Science, 367, 2020
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1G60
| Crystal Structure of Methyltransferase MboIIa (Moraxella bovis) | Descriptor: | Adenine-specific Methyltransferase MboIIA, S-ADENOSYLMETHIONINE, SODIUM ION | Authors: | Osipiuk, J, Walsh, M.A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2000-11-02 | Release date: | 2002-05-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Crystal structure of MboIIA methyltransferase. Nucleic Acids Res., 31, 2003
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7L69
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2KW3
| Heterotrimeric interaction between RFX5 and RFXAP | Descriptor: | DNA-binding protein RFX5, Regulatory factor X-associated protein | Authors: | Laird, K.M, Briggs, L.L, Boss, J.M, Summers, M.F, Garvie, C.W. | Deposit date: | 2010-03-30 | Release date: | 2010-08-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the heterotrimeric complex between RFX5 and RFXAP
reveals molecular details associated with MHCII gene expression To be Published
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7LCD
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8T9X
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8T9C
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8EUJ
| Class2 of the INO80-Nucleosome complex | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | Deposit date: | 2022-10-18 | Release date: | 2023-07-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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8EUE
| Class1 of the INO80-Nucleosome complex | Descriptor: | DNA (147-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Wu, H, Munoz, E, Gourdet, M, Narlikar, G, Cheng, Y.F. | Deposit date: | 2022-10-18 | Release date: | 2023-07-12 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility. Science, 381, 2023
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4JXT
| CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION | Authors: | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | Deposit date: | 2013-03-28 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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7BUM
| mcGAS bound with pGpA | Descriptor: | ADENOSINE MONOPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, ... | Authors: | Wang, B, Su, X.D. | Deposit date: | 2020-04-07 | Release date: | 2020-09-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.047 Å) | Cite: | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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7BUQ
| mcGAS bound with 23-cGAMP | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | Authors: | Wang, B, Su, X.D. | Deposit date: | 2020-04-07 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.091 Å) | Cite: | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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8TJE
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7WI7
| Crystal structure of human MCM8/9 complex | Descriptor: | DNA helicase MCM8, DNA helicase MCM9, ZINC ION | Authors: | Li, J, Liu, Y. | Deposit date: | 2022-01-03 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (6.6 Å) | Cite: | Crystal structure of human MCM8/9 complex To Be Published
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1AGO
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1AGZ
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7Z42
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4Z5T
| The nucleosome containing human H3.5 | Descriptor: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H. | Deposit date: | 2015-04-03 | Release date: | 2016-02-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin, 9, 2016
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1AGK
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4K4V
| Poliovirus polymerase elongation complex (r5+1_form) | Descriptor: | DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL, ... | Authors: | Gong, P, Peersen, O.B. | Deposit date: | 2013-04-12 | Release date: | 2013-05-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
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8JR8
| MapSPARTA dimer bound with guide-target | Descriptor: | DNA (25-MER), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... | Authors: | Huang, P.P, Li, Z.X, Guo, L.J, Xiao, Y.B, Chen, M.R. | Deposit date: | 2023-06-16 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Cryo-EM Structure of MapSPARTA To Be Published
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1AGH
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1QKL
| hRPABC14.4, essential subunit of human RNA polymerases I, II and III | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE | Authors: | Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. | Deposit date: | 1999-07-26 | Release date: | 1999-11-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
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1ZAY
| PURINE REPRESSOR-HYPOXANTHINE-MODIFIED-PURF-OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*TP*(1AP)P*TP*TP*TP*TP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) | Authors: | Zheleznova, E.E, Brennan, R.G. | Deposit date: | 1998-12-16 | Release date: | 1999-12-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The Roles of Exocyclic Groups in the Central Base-Pair Step in Modulating the Affinity of PurR for its Operator To be Published
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8UFK
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