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8TJG
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BU of 8tjg by Molmil
Structure of Nei2 from Mycobacterium smegmatis in complex with Zn2+
Descriptor: DNA-(apurinic or apyrimidinic site) lyase, ZINC ION
Authors:Warren, G, Shuman, S.
Deposit date:2023-07-21
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of Nei2 from Mycobacterium smegmatis in complex with Zn2+
To Be Published
2MW8
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BU of 2mw8 by Molmil
Solution structure of SATB1 homeodomain
Descriptor: DNA-binding protein SATB1
Authors:Yamasaki, K, Yamasaki, T.
Deposit date:2014-10-31
Release date:2015-11-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of SATB1 homeodomain
To be Published
5OD6
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BU of 5od6 by Molmil
Crystal structure of Smad3-MH1 bound to the GGCGC site.
Descriptor: DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 3, ZINC ION
Authors:Kaczmarska, Z, Marquez, J.A, Macias, M.J.
Deposit date:2017-07-04
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Nat Commun, 8, 2017
6EKM
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BU of 6ekm by Molmil
Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site
Descriptor: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B
Authors:Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T.
Deposit date:2017-09-26
Release date:2018-10-10
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Crystal structure of mammalian Rev7 in complex with human Rev3
To Be Published
6UML
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BU of 6uml by Molmil
Structural Basis for Thalidomide Teratogenicity Revealed by the Cereblon-DDB1-SALL4-Pomalidomide Complex
Descriptor: DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ...
Authors:Clayton, T.L, Matyskiela, M.E, Pagarigan, B.E, Tran, E.T, Chamberlain, P.P.
Deposit date:2019-10-09
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex.
Nat.Struct.Mol.Biol., 27, 2020
7S3C
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BU of 7s3c by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-A5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*AP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Glasser, E, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
7S3A
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BU of 7s3a by Molmil
Crystal structure of intact U2AF65 RRM-region bound to AdML-C5 oligonucleotide
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*CP*U)-D(P*(BRU))-R(P*CP*C)-3'), SODIUM ION, Splicing factor U2AF 65 kDa subunit
Authors:Jenkins, J.L, Henderson, S, Kielkopf, C.L.
Deposit date:2021-09-05
Release date:2022-05-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal.
Nucleic Acids Res., 50, 2022
4KA4
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BU of 4ka4 by Molmil
Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
Descriptor: DNA (5'-D(*TP*CP*GP*CP*GP*CP*G)-3'), Z-DNA-binding protein 1
Authors:Athanasiadis, A, de Rosa, M, De Sanctis, D.
Deposit date:2013-04-22
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a proteolytically defined Zbeta domain of human DAI (ZBP1, DLM-1)
To be Published
2KV6
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BU of 2kv6 by Molmil
Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether
Descriptor: 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide
Authors:Huang, H, Kozekov, I.D, Kozekova, A, Rizzo, C.J, McCullough, A, LLoyd, R.S, Stone, M.P.
Deposit date:2010-03-08
Release date:2010-07-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage .
Biochemistry, 49, 2010
7O1E
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BU of 7o1e by Molmil
Crystal structure of PCNA from Chaetomium thermophilum
Descriptor: Proliferating cell nuclear antigen
Authors:Alphey, M.A, MacNeill, S, Yang, D.
Deposit date:2021-03-29
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
7O1F
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BU of 7o1f by Molmil
PCNA from Chaetomium thermophilum in complex with PolD4 PIP peptide
Descriptor: Peptide fragment from PolD4, Proliferating cell nuclear antigen, SODIUM ION
Authors:Alphey, M.A, MacNeill, S, Yang, D.
Deposit date:2021-03-29
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix.
Febs J., 290, 2023
3JA8
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BU of 3ja8 by Molmil
Cryo-EM structure of the MCM2-7 double hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ...
Authors:Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N.
Deposit date:2015-05-09
Release date:2015-08-05
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the eukaryotic MCM complex at 3.8 angstrom
Nature, 524, 2015
2KLO
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BU of 2klo by Molmil
Structure of the Cdt1 C-terminal domain
Descriptor: DNA replication factor Cdt1
Authors:Khayrutdinov, B.I, Bae, W.J, Yun, Y.M, Tsuyama, T, Kim, J.J, Hwang, E, Ryu, K.-S, Cheong, H.-K, Cheong, C, Karplus, P.A, Guntert, P, Tada, S, Jeon, Y.H, Cho, Y.
Deposit date:2009-07-06
Release date:2009-10-13
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
2CKC
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BU of 2ckc by Molmil
Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction
Descriptor: CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7
Authors:Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E.
Deposit date:2006-04-14
Release date:2007-05-08
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
8TK7
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BU of 8tk7 by Molmil
Myxococcus xanthus EncA protein shell with compartmentalized SNAP-tag cargo protein
Descriptor: Methylated-DNA--protein-cysteine methyltransferase, Type 1 encapsulin shell protein EncA
Authors:Andreas, M.P, Kwon, S, Giessen, T.W.
Deposit date:2023-07-25
Release date:2023-09-13
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:Structure and heterogeneity of a highly cargo-loaded encapsulin shell.
J.Struct.Biol., 215, 2023
8K87
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BU of 8k87 by Molmil
Dimer structure of procaryotic Ago
Descriptor: DNA (41-mer), MAGNESIUM ION, Piwi domain protein, ...
Authors:Gao, X, Sun, D, Cui, S, Wang, Y.
Deposit date:2023-07-29
Release date:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural Basis of prokaryotic Argonaute System
To Be Published
8EVG
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BU of 8evg by Molmil
162bp CX3CR1 nucleosome (further classified with better nucleosome end)
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Tengfei, L, Ruifang, G, Yawen, B.
Deposit date:2022-10-20
Release date:2023-11-01
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural basis of cooperative targeting of the CX3CR1 nucleosome
To Be Published
8TNP
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BU of 8tnp by Molmil
Cryo-EM structure of DDB1dB:CRBN:Pomalidomide:SD40
Descriptor: DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, Protein cereblon, ...
Authors:Roy Burman, S.S, Hunkeler, M, Fischer, E.S.
Deposit date:2023-08-02
Release date:2024-03-13
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Continuous evolution of compact protein degradation tags regulated by selective molecular glues.
Science, 383, 2024
5MKW
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BU of 5mkw by Molmil
Crystal structure of the human ZRANB3 HNH domain
Descriptor: DNA annealing helicase and endonuclease ZRANB3, GLYCEROL, ZINC ION
Authors:Ariza, A.
Deposit date:2016-12-05
Release date:2017-06-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
6H0G
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BU of 6h0g by Molmil
Structure of the DDB1-CRBN-pomalidomide complex bound to ZNF692(ZF4)
Descriptor: DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DDB1 (DNA damage binding protein 1),DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ...
Authors:Bunker, R.D, Petzold, G, Thoma, N.H.
Deposit date:2018-07-09
Release date:2018-11-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.25 Å)
Cite:Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Science, 362, 2018
5WCE
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BU of 5wce by Molmil
Caulobacter crescentus pol III beta
Descriptor: DNA polymerase III subunit beta
Authors:Oakley, A.J.
Deposit date:2017-06-30
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Pol III beta from Caulobacter crescentus
To Be Published
6A1O
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BU of 6a1o by Molmil
Crystal structures of disordered Z-type helices
Descriptor: DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ...
Authors:Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N.
Deposit date:2018-06-07
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38, 2019
6A1Q
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BU of 6a1q by Molmil
Crystal structures of disordered Z-type helices
Descriptor: DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*G)-3')
Authors:Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N.
Deposit date:2018-06-07
Release date:2019-01-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38, 2019
6MC6
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BU of 6mc6 by Molmil
Crystal structure of PprA filament from Deinococcus radiodurans
Descriptor: DNA repair protein PprA
Authors:Szabla, R, Junop, M.S, Wood, K.
Deposit date:2018-08-30
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.747 Å)
Cite:Crystal structure of PprA from Deinococcus radiodurans
To Be Published
4XZQ
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BU of 4xzq by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
Descriptor: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
Deposit date:2015-02-04
Release date:2015-10-14
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015

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数据于2024-09-04公开中

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