8TJG
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2MW8
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5OD6
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6EKM
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6UML
| Structural Basis for Thalidomide Teratogenicity Revealed by the Cereblon-DDB1-SALL4-Pomalidomide Complex | Descriptor: | DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | Authors: | Clayton, T.L, Matyskiela, M.E, Pagarigan, B.E, Tran, E.T, Chamberlain, P.P. | Deposit date: | 2019-10-09 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.58 Å) | Cite: | Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex. Nat.Struct.Mol.Biol., 27, 2020
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7S3C
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7S3A
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4KA4
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2KV6
| Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether | Descriptor: | 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide | Authors: | Huang, H, Kozekov, I.D, Kozekova, A, Rizzo, C.J, McCullough, A, LLoyd, R.S, Stone, M.P. | Deposit date: | 2010-03-08 | Release date: | 2010-07-21 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage . Biochemistry, 49, 2010
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7O1E
| Crystal structure of PCNA from Chaetomium thermophilum | Descriptor: | Proliferating cell nuclear antigen | Authors: | Alphey, M.A, MacNeill, S, Yang, D. | Deposit date: | 2021-03-29 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix. Febs J., 290, 2023
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7O1F
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3JA8
| Cryo-EM structure of the MCM2-7 double hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Minichromosome Maintenance 2, Minichromosome Maintenance 3, ... | Authors: | Li, N, Zhai, Y, Zhang, Y, Li, W, Yang, M, Lei, J, Tye, B.K, Gao, N. | Deposit date: | 2015-05-09 | Release date: | 2015-08-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the eukaryotic MCM complex at 3.8 angstrom Nature, 524, 2015
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2KLO
| Structure of the Cdt1 C-terminal domain | Descriptor: | DNA replication factor Cdt1 | Authors: | Khayrutdinov, B.I, Bae, W.J, Yun, Y.M, Tsuyama, T, Kim, J.J, Hwang, E, Ryu, K.-S, Cheong, H.-K, Cheong, C, Karplus, P.A, Guntert, P, Tada, S, Jeon, Y.H, Cho, Y. | Deposit date: | 2009-07-06 | Release date: | 2009-10-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors Protein Sci., 18, 2009
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2CKC
| Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction | Descriptor: | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7 | Authors: | Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E. | Deposit date: | 2006-04-14 | Release date: | 2007-05-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction To be Published
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8TK7
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8K87
| Dimer structure of procaryotic Ago | Descriptor: | DNA (41-mer), MAGNESIUM ION, Piwi domain protein, ... | Authors: | Gao, X, Sun, D, Cui, S, Wang, Y. | Deposit date: | 2023-07-29 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural Basis of prokaryotic Argonaute System To Be Published
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8EVG
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8TNP
| Cryo-EM structure of DDB1dB:CRBN:Pomalidomide:SD40 | Descriptor: | DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, Protein cereblon, ... | Authors: | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | Deposit date: | 2023-08-02 | Release date: | 2024-03-13 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science, 383, 2024
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5MKW
| Crystal structure of the human ZRANB3 HNH domain | Descriptor: | DNA annealing helicase and endonuclease ZRANB3, GLYCEROL, ZINC ION | Authors: | Ariza, A. | Deposit date: | 2016-12-05 | Release date: | 2017-06-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the function of ZRANB3 in replication stress response. Nat Commun, 8, 2017
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6H0G
| Structure of the DDB1-CRBN-pomalidomide complex bound to ZNF692(ZF4) | Descriptor: | DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DDB1 (DNA damage binding protein 1),DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... | Authors: | Bunker, R.D, Petzold, G, Thoma, N.H. | Deposit date: | 2018-07-09 | Release date: | 2018-11-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.25 Å) | Cite: | Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science, 362, 2018
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5WCE
| Caulobacter crescentus pol III beta | Descriptor: | DNA polymerase III subunit beta | Authors: | Oakley, A.J. | Deposit date: | 2017-06-30 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Pol III beta from Caulobacter crescentus To Be Published
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6A1O
| Crystal structures of disordered Z-type helices | Descriptor: | DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ... | Authors: | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | Deposit date: | 2018-06-07 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
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6A1Q
| Crystal structures of disordered Z-type helices | Descriptor: | DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*GP*TP*G)-3') | Authors: | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | Deposit date: | 2018-06-07 | Release date: | 2019-01-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal structures of disordered Z-type helices. Nucleosides Nucleotides Nucleic Acids, 38, 2019
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6MC6
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4XZQ
| Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis | Descriptor: | DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B. | Deposit date: | 2015-02-04 | Release date: | 2015-10-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF. Mol.Cell.Biol., 35, 2015
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