7Y82
 
 | | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA complex bound to self RNA target | | Descriptor: | MAGNESIUM ION, RAMP superfamily protein, Self RNA target, ... | | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | | Deposit date: | 2022-06-22 | | Release date: | 2022-12-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
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7Y83
 | | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease bound to non-self RNA target | | Descriptor: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | | Deposit date: | 2022-06-22 | | Release date: | 2022-12-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
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7Y84
 | | CryoEM structure of type III-E CRISPR Craspase gRAMP-crRNA in complex with TPR-CHAT protease | | Descriptor: | CHAT domain protein, MAGNESIUM ION, RAMP superfamily protein, ... | | Authors: | Zhang, J.T, Cui, N, Huang, H.D, Jia, N. | | Deposit date: | 2022-06-22 | | Release date: | 2022-12-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase.
Nat Commun, 13, 2022
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3HFO
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3UCA
 | | Crystal structure of isoprenoid synthase (target EFI-501974) from clostridium perfringens | | Descriptor: | Geranyltranstransferase | | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2011-10-26 | | Release date: | 2011-11-16 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
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7QTV
 | | Beryllium fluoride form of the Na+,K+-ATPase (E2-BeFx) | | Descriptor: | 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shahsavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. | | Deposit date: | 2022-01-16 | | Release date: | 2022-11-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (4.05 Å) | | Cite: | The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state.
J.Biol.Chem., 298, 2022
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2XHZ
 | | Probing the active site of the sugar isomerase domain from E. coli arabinose-5-phosphate isomerase via X-ray crystallography | | Descriptor: | ARABINOSE 5-PHOSPHATE ISOMERASE | | Authors: | Gourlay, L.J, Sommaruga, S, Nardini, M, Sperandeo, P, Deho, G, Polissi, A, Bolognesi, M. | | Deposit date: | 2010-06-24 | | Release date: | 2011-01-26 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Probing the Active Site of the Sugar Isomerase Domain from E. Coli Arabinose-5-Phosphate Isomerase Via X-Ray Crystallography.
Protein Sci., 19, 2010
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3UKI
 | | Crystal structure of reduced OxyR from Porphyromonas gingivalis | | Descriptor: | OxyR | | Authors: | Svintradze, D.V, Wright, H.T, Collazo-Santiago, E.A, Lewis, J.P. | | Deposit date: | 2011-11-09 | | Release date: | 2013-07-31 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (4.15 Å) | | Cite: | Structures of the Porphyromonas gingivalis OxyR regulatory domain explain differences in expression of the OxyR regulon in Escherichia coli and P. gingivalis.
Acta Crystallogr.,Sect.D, 69, 2013
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6K0R
 | | Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin | | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Zhang, W, Chen, L, Li, W, Ju, D, Huang, N, Zhang, E. | | Deposit date: | 2019-05-07 | | Release date: | 2020-05-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
Sci Transl Med, 12, 2020
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4V7K
 | | Structure of RelE nuclease bound to the 70S ribosome (postcleavage state) | | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | Authors: | Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E. | | Deposit date: | 2009-11-02 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
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2Y41
 | | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with IPM and MN | | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, 3-ISOPROPYLMALIC ACID, MANGANESE (II) ION | | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | | Deposit date: | 2011-01-04 | | Release date: | 2011-01-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase.
Mol.Biosyst., 7, 2011
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4V6A
 | | Structure of EF-P bound to the 70S ribosome. | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Stanley, R.E, Blaha, G. | | Deposit date: | 2009-06-15 | | Release date: | 2014-07-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome.
Science, 325, 2009
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3UR0
 | | Crystal structures of murine norovirus RNA-dependent RNA polymerase in complex with Suramin | | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, RNA-dependent RNA polymerase, SULFATE ION | | Authors: | Milani, M, Mastrangelo, E, Bolognesi, M. | | Deposit date: | 2011-11-21 | | Release date: | 2012-05-02 | | Last modified: | 2012-05-23 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
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2Y42
 | | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with NADH and Mn | | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, BICINE, MANGANESE (II) ION, ... | | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | | Deposit date: | 2011-01-04 | | Release date: | 2011-01-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase.
Mol.Biosyst., 7, 2011
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2Y3Z
 | | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - apo enzyme | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-ISOPROPYLMALATE DEHYDROGENASE, GLYCEROL, ... | | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | | Deposit date: | 2011-01-04 | | Release date: | 2011-01-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase.
Mol.Biosyst., 7, 2011
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2Y40
 | | Structure of Isopropylmalate dehydrogenase from Thermus thermophilus - complex with Mn | | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, MANGANESE (II) ION | | Authors: | Graczer, E, merlin, A, Singh, R.K, Manikandan, K, Zavodsky, P, Weiss, M.S, Vas, M. | | Deposit date: | 2011-01-04 | | Release date: | 2011-01-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Atomic Level Description of the Domain Closure in a Dimeric Enzyme: Thermus Thermophilus 3-Isopropylmalate Dehydrogenase.
Mol.Biosyst., 7, 2011
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5CRO
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8EEE
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8S5N
 | | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-24 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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9JDW
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8S55
 | | RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-22 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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8S51
 | | RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-22 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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8SBH
 | | YeiE effector binding domain from E. coli | | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | | Authors: | Momany, C, Nune, M, Brondani, J.C, Afful, D, Neidle, E. | | Deposit date: | 2023-04-03 | | Release date: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | FinR, a LysR-type transcriptional regulator involved in sulfur homeostasis with homologs in diverse microorganisms
To Be Published
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8S52
 | | RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-22 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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8RTZ
 | | The structure of E. coli penicillin binding protein 3 (PBP3) in complex with a bicyclic peptide inhibitor | | Descriptor: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, Bicyclic peptide inhibitor, Peptidoglycan D,D-transpeptidase FtsI | | Authors: | Newman, H, Rowland, C.E, Dods, R, Lewis, N, Stanway, S.J, Bellini, D, Beswick, P. | | Deposit date: | 2024-01-29 | | Release date: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle) Antimicrobial Inhibitor of Escherichia coli PBP3
To Be Published
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