8A3D
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![BU of 8a3d by Molmil](/molmil-images/mine/8a3d) | Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | Descriptor: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Faille, A, Warren, A.J, Dent, K.C. | Deposit date: | 2022-06-08 | Release date: | 2023-03-08 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (1.67 Å) | Cite: | The chemical landscape of the human ribosome at 1.67 angstrom resolution. Biorxiv, 2023
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8INK
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![BU of 8ink by Molmil](/molmil-images/mine/8ink) | human nuclear pre-60S ribosomal particle - State D | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-10 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IE3
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![BU of 8ie3 by Molmil](/molmil-images/mine/8ie3) | human nuclear pre-60S ribosomal particle - State E | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-15 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IDY
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![BU of 8idy by Molmil](/molmil-images/mine/8idy) | |
8IPD
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![BU of 8ipd by Molmil](/molmil-images/mine/8ipd) | human nuclear pre-60S ribosomal particle - State C | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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8IDT
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![BU of 8idt by Molmil](/molmil-images/mine/8idt) | human nuclear pre-60S ribosomal particle - State G | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-02-14 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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6ID1
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![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6CKC
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![BU of 6ckc by Molmil](/molmil-images/mine/6ckc) | Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity | Descriptor: | 7-[(5R)-5-C-phenyl-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Methylosome protein 50, Protein arginine N-methyltransferase 5 | Authors: | Antonysamy, S. | Deposit date: | 2018-02-27 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity. ACS Med Chem Lett, 9, 2018
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8IR1
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![BU of 8ir1 by Molmil](/molmil-images/mine/8ir1) | human nuclear pre-60S ribosomal particle - State A | Descriptor: | 28S rRNA, 5.8S rRMA, 5S RNA, ... | Authors: | Zhang, Y, Gao, N. | Deposit date: | 2023-03-17 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles. Cell Res., 33, 2023
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7OBR
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![BU of 7obr by Molmil](/molmil-images/mine/7obr) | RNC-SRP early complex | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Ban, N. | Deposit date: | 2021-04-23 | Release date: | 2021-07-21 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle. Cell Rep, 36, 2021
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4II2
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![BU of 4ii2 by Molmil](/molmil-images/mine/4ii2) | Crystal structure of Ubiquitin activating enzyme 1 (Uba1) in complex with the Ub E2 Ubc4, ubiquitin, and ATP/Mg | Descriptor: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Olsen, S.K, Lima, C.D. | Deposit date: | 2012-12-19 | Release date: | 2013-02-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a ubiquitin E1-E2 complex: insights to E1-E2 thioester transfer. Mol.Cell, 49, 2013
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4IP3
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![BU of 4ip3 by Molmil](/molmil-images/mine/4ip3) | Complex structure of OspI and Ubc13 | Descriptor: | ORF169b, Ubiquitin-conjugating enzyme E2 N | Authors: | Fu, P, Jin, M, Zhang, X, Xu, L, Xia, Z, Zhu, Y. | Deposit date: | 2013-01-09 | Release date: | 2013-03-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure Analysis of Ubc13 Inactivation To be Published
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4V8P
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![BU of 4v8p by Molmil](/molmil-images/mine/4v8p) | T.thermophila 60S ribosomal subunit in complex with initiation factor 6. | Descriptor: | 26S RRNA, 5.8S RRNA, 5S RRNA, ... | Authors: | Klinge, S, Voigts-Hoffmann, F, Leibundgut, M, Arpagaus, S, Ban, N. | Deposit date: | 2011-09-14 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6. Science, 334, 2011
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4II3
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![BU of 4ii3 by Molmil](/molmil-images/mine/4ii3) | |
6W2T
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![BU of 6w2t by Molmil](/molmil-images/mine/6w2t) | Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2) | Descriptor: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | Authors: | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | Deposit date: | 2020-03-08 | Release date: | 2020-04-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife, 9, 2020
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4V88
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![BU of 4v88 by Molmil](/molmil-images/mine/4v88) | The structure of the eukaryotic ribosome at 3.0 A resolution. | Descriptor: | 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... | Authors: | Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. | Deposit date: | 2011-10-11 | Release date: | 2014-07-09 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
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8Y0W
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![BU of 8y0w by Molmil](/molmil-images/mine/8y0w) | |
8Y0X
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![BU of 8y0x by Molmil](/molmil-images/mine/8y0x) | Dormant ribosome with SERBP1 | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | Authors: | Du, M, Zeng, F. | Deposit date: | 2024-01-23 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The global structure of dormant ribosome To Be Published
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8XXN
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![BU of 8xxn by Molmil](/molmil-images/mine/8xxn) | Cryo-EM structure of the human 43S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXL
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![BU of 8xxl by Molmil](/molmil-images/mine/8xxl) | Cryo-EM structure of the human 40S ribosome with PDCD4 | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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8XXM
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![BU of 8xxm by Molmil](/molmil-images/mine/8xxm) | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | Descriptor: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | Deposit date: | 2024-01-18 | Release date: | 2024-05-01 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
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4V8Y
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![BU of 4v8y by Molmil](/molmil-images/mine/4v8y) | Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | Descriptor: | 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... | Authors: | Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. | Deposit date: | 2013-07-20 | Release date: | 2014-07-09 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
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4UG0
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![BU of 4ug0 by Molmil](/molmil-images/mine/4ug0) | STRUCTURE OF THE HUMAN 80S RIBOSOME | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... | Authors: | Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. | Deposit date: | 2015-03-20 | Release date: | 2015-06-10 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the human 80S ribosome NATURE, 520, 2015
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11AS
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![BU of 11as by Molmil](/molmil-images/mine/11as) | |
2HZ7
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![BU of 2hz7 by Molmil](/molmil-images/mine/2hz7) | Crystal structure of the Glutaminyl-tRNA synthetase from Deinococcus radiodurans | Descriptor: | Glutaminyl-tRNA synthetase | Authors: | Deniziak, M, Sauter, C, Becker, H.D, Paulus, C, Giege, R, Kern, D. | Deposit date: | 2006-08-08 | Release date: | 2007-04-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Deinococcus glutaminyl-tRNA synthetase is a chimer between proteins from an ancient and the modern pathways of aminoacyl-tRNA formation Nucleic Acids Res., 35, 2007
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