8KFU
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![BU of 8kfu by Molmil](/molmil-images/mine/8kfu) | Crystal structure of ZmMOC1 in complex with a nicked Holliday junction soaked in Mn2+ for 180 seconds | Descriptor: | 1,2-ETHANEDIOL, DNA (25-MER), DNA (33-MER), ... | Authors: | Zhang, D, Luo, Z, Lin, Z. | Deposit date: | 2023-08-16 | Release date: | 2024-06-26 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
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8KFV
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![BU of 8kfv by Molmil](/molmil-images/mine/8kfv) | Crystal structure of ZmMOC1 K229A in complex with a nicked Holliday junction soaked in Mn2+ for 180 seconds | Descriptor: | 1,2-ETHANEDIOL, DNA (25-MER), DNA (33-MER), ... | Authors: | Zhang, D, Luo, Z, Lin, Z. | Deposit date: | 2023-08-16 | Release date: | 2024-06-26 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
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5TGG
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![BU of 5tgg by Molmil](/molmil-images/mine/5tgg) | |
8KFR
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![BU of 8kfr by Molmil](/molmil-images/mine/8kfr) | Crystal structure of ZmMOC1/nicked Holliday junction/Ca2+ complex | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (25-MER), ... | Authors: | Zhang, D, Luo, Z, Lin, Z. | Deposit date: | 2023-08-16 | Release date: | 2024-06-26 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions. Nat Commun, 15, 2024
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5HGO
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![BU of 5hgo by Molmil](/molmil-images/mine/5hgo) | Hexameric HIV-1 CA R18G mutant | Descriptor: | Capsid protein P24 | Authors: | Jacques, D.A, James, L.C. | Deposit date: | 2016-01-08 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
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7D69
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![BU of 7d69 by Molmil](/molmil-images/mine/7d69) | Cryo-EM structure of the nucleosome containing Giardia histones | Descriptor: | 601L DNA (145-MER), Histone H2A, Histone H2B, ... | Authors: | Sato, S, Takizawa, Y, Kurumizaka, H. | Deposit date: | 2020-09-29 | Release date: | 2021-09-08 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones. Nucleic Acids Res., 49, 2021
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4BJT
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![BU of 4bjt by Molmil](/molmil-images/mine/4bjt) | Crystal structure of the Rap1 C-terminal domain (Rap1-RCT) in complex with the Rap1 binding module of Rif1 (Rif1-RBM) | Descriptor: | 1,2-ETHANEDIOL, DNA-BINDING PROTEIN RAP1, TELOMERE LENGTH REGULATOR PROTEIN RIF1 | Authors: | Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H. | Deposit date: | 2013-04-19 | Release date: | 2013-06-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions Cell(Cambridge,Mass.), 153, 2013
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5HGN
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![BU of 5hgn by Molmil](/molmil-images/mine/5hgn) | Hexameric HIV-1 CA, apo form | Descriptor: | Capsid protein P24 | Authors: | Jacques, D.A, Price, A.J, James, D.A. | Deposit date: | 2016-01-08 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
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5VBJ
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![BU of 5vbj by Molmil](/molmil-images/mine/5vbj) | |
4E4W
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![BU of 4e4w by Molmil](/molmil-images/mine/4e4w) | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | Authors: | Gueneau, E, Legrand, P, Charbonnier, J.B. | Deposit date: | 2012-03-13 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site. Nat.Struct.Mol.Biol., 20, 2013
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5HGL
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![BU of 5hgl by Molmil](/molmil-images/mine/5hgl) | Hexameric HIV-1 CA, open conformation | Descriptor: | CHLORIDE ION, Capsid protein P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE | Authors: | Price, A.J, Jacques, D.A, James, L.C. | Deposit date: | 2016-01-08 | Release date: | 2016-08-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature, 536, 2016
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1NHI
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![BU of 1nhi by Molmil](/molmil-images/mine/1nhi) | Crystal structure of N-terminal 40KD MutL (LN40) complex with ADPnP and one potassium | Descriptor: | 1,2-ETHANEDIOL, DNA mismatch repair protein mutL, MAGNESIUM ION, ... | Authors: | Hu, X, Machius, M, Yang, W. | Deposit date: | 2002-12-19 | Release date: | 2003-06-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
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5VXQ
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![BU of 5vxq by Molmil](/molmil-images/mine/5vxq) | X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5 | Descriptor: | AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3') | Authors: | Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K. | Deposit date: | 2017-05-23 | Release date: | 2017-08-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.002 Å) | Cite: | Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA. Nucleic Acids Res., 45, 2017
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1U0C
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![BU of 1u0c by Molmil](/molmil-images/mine/1u0c) | Y33C Mutant of Homing endonuclease I-CreI | Descriptor: | 5'-D(*CP*GP*TP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*AP*GP*C)-3', 5'-D(*GP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*AP*CP*G)-3', DNA endonuclease I-CreI, ... | Authors: | Sussman, D, Chadsey, M, Fauce, S, Engel, A, Bruett, A, Monnat, R, Stoddard, B.L, Seligman, L.M. | Deposit date: | 2004-07-13 | Release date: | 2004-11-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Isolation and characterization of new homing endonuclease specificities at individual target site positions. J.Mol.Biol., 342, 2004
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3VAG
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![BU of 3vag by Molmil](/molmil-images/mine/3vag) | Structure of U2AF65 variant with BrU3C2 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*U*CP*(BRU)P*UP*UP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAK
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![BU of 3vak by Molmil](/molmil-images/mine/3vak) | Structure of U2AF65 variant with BrU5 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2017-08-16 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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1AG5
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![BU of 1ag5 by Molmil](/molmil-images/mine/1ag5) | THE SOLUTION STRUCTURE OF AN AFLATOXIN B1 EPOXIDE ADDUCT AT THE N7 POSITION OF GUANINE OPPOSITE AN ADENINE IN THE COMPLEMENTARY STRAND OF AN OLIGODEOXYNUCLEOTIDE DUPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1, DNA (5'-D(*CP*CP*AP*TP*CP*GP*AP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*TP*CP*AP*GP*AP*TP*GP*G)-3') | Authors: | Johnson, D.S, Stone, M.P. | Deposit date: | 1997-04-01 | Release date: | 1997-09-17 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Refined solution structure of 8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the complementary strand of an oligodeoxynucleotide duplex as determined by 1H NMR. Biochemistry, 34, 1995
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5BMM
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![BU of 5bmm by Molmil](/molmil-images/mine/5bmm) | Src in complex with DNA-templated macrocyclic inhibitor MC25b | Descriptor: | Proto-oncogene tyrosine-protein kinase Src, macrocyclic inhibitor MC25b | Authors: | Georghiou, G, Guja, K.E, Aleem, S, Kleiner, R.E, Liu, D.R, Miller, W.T, Garcia-Diaz, M, Seeliger, M.A. | Deposit date: | 2015-05-22 | Release date: | 2016-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chem Biol, 23, 2016
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6EVV
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![BU of 6evv by Molmil](/molmil-images/mine/6evv) | X-ray structure of the complex between human alpha thrombin and NU172, a duplex/quadruplex 26-mer DNA aptamer, in the presence of potassium ions. | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Troisi, R, Russo Krauss, I, Sica, F. | Deposit date: | 2017-11-02 | Release date: | 2018-10-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer. Nucleic Acids Res., 46, 2018
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6GN7
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![BU of 6gn7 by Molmil](/molmil-images/mine/6gn7) | X-ray structure of the complex between human alpha thrombin and NU172, a duplex/quadruplex 26-mer DNA aptamer, in the presence of sodium ions. | Descriptor: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Troisi, R, Russo Krauss, I, Sica, F. | Deposit date: | 2018-05-30 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer. Nucleic Acids Res., 46, 2018
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2F1J
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![BU of 2f1j by Molmil](/molmil-images/mine/2f1j) | Recombinase in Complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA repair and recombination protein radA, MAGNESIUM ION | Authors: | Qian, X, He, Y, Wu, Y, Luo, Y. | Deposit date: | 2005-11-14 | Release date: | 2006-05-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Asp302 determines potassium dependence of a RadA recombinase from Methanococcus voltae. J.Mol.Biol., 360, 2006
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1HT7
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![BU of 1ht7 by Molmil](/molmil-images/mine/1ht7) | |
3VAH
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![BU of 3vah by Molmil](/molmil-images/mine/3vah) | Structure of U2AF65 variant with BrU3C4 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(P*UP*UP*(BRU)P*CP*UP*UP*U)-3', GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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3VAM
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![BU of 3vam by Molmil](/molmil-images/mine/3vam) | Structure of U2AF65 variant with BrU5C2 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*CP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... | Authors: | Jenkins, J.L, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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2JSL
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![BU of 2jsl by Molmil](/molmil-images/mine/2jsl) | Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-08 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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