PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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2N3Q	NMR structure of the II-III-VI three-way junction from the VS ribozyme Descriptor: RNA (62-MER) Authors: Bonneau, E, Girard, N, Lemieux, S, Legault, P. Deposit date: 2015-06-09 Release date: 2015-07-15 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The NMR structure of the II-III-VI three-way junction from the Neurospora VS ribozyme reveals a critical tertiary interaction and provides new insights into the global ribozyme structure. Rna, 21, 2015
1DUH	CRYSTAL STRUCTURE OF THE CONSERVED DOMAIN IV OF E. COLI 4.5S RNA Descriptor: 4.5S RNA DOMAIN IV, LUTETIUM (III) ION, MAGNESIUM ION, ... Authors: Jovine, L, Hainzl, T, Oubridge, C, Scott, W.G, Li, J, Sixma, T.K, Wonacott, A, Skarzynski, T, Nagai, K. Deposit date: 2000-01-17 Release date: 2000-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of the ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA. Structure Fold.Des., 8, 2000
8XMD	Pre-translocated Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XMC	Post-translocated Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XMB	NTP-bound Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XME	Backtracked Pol IV transcription elongation complex Descriptor: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... Authors: Huang, K, Fang, C.L, Zhang, Y. Deposit date: 2023-12-27 Release date: 2024-07-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
5UI8	structure of sigmaN-holoenzyme Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Darst, S.A, Campbell, E.A. Deposit date: 2017-01-13 Release date: 2017-02-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.76 Å) Cite: Crystal structure of Aquifex aeolicus sigma (N) bound to promoter DNA and the structure of sigma (N)-holoenzyme. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7ZSA	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2022-05-06 Release date: 2022-11-16 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7ZS9	Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A) Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... Authors: Wang, H, Cramer, P. Deposit date: 2022-05-06 Release date: 2022-11-16 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structures of transcription preinitiation complex engaged with the +1 nucleosome. Nat.Struct.Mol.Biol., 30, 2023
3ERC	Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase with three fragments of RNA and 3'-deoxy ATP Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, ... Authors: Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. Deposit date: 2008-10-01 Release date: 2009-06-16 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.21 Å) Cite: Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
2ILZ	Crystal structure of poliovirus polymerase complexed with GTP and Mn2+ Descriptor: ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2006-10-03 Release date: 2006-12-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions. J.Mol.Biol., 366, 2007
3ER8	Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with two fragments of RNA Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, Poly(A) polymerase catalytic subunit, RNA/DNA chimera 5'-D(CP*CP*)R(UP*UP*)D(C)-3', ... Authors: Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. Deposit date: 2008-10-01 Release date: 2009-06-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.18 Å) Cite: Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
2IM0	Crystal structure of poliovirus polymerase complexed with CTP and Mg2+ Descriptor: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, SODIUM ION, ... Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2006-10-03 Release date: 2006-12-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions. J.Mol.Biol., 366, 2007
2IM1	Crystal structure of poliovirus polymerase complexed with CTP and Mn2+ Descriptor: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2006-10-03 Release date: 2006-12-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions. J.Mol.Biol., 366, 2007
2IM3	Crystal structure of poliovirus polymerase complexed with UTP and Mn2+ Descriptor: ACETIC ACID, MANGANESE (II) ION, SODIUM ION, ... Authors: Thompson, A.A, Peersen, O.B. Deposit date: 2006-10-03 Release date: 2006-12-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions. J.Mol.Biol., 366, 2007
3ER9	Crystal structure of the heterodimeric vaccinia virus mRNA polyadenylate polymerase complex with UU and 3'-deoxy ATP Descriptor: 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-R(UP*U)-3', CALCIUM ION, ... Authors: Li, C, Li, H, Zhou, S, Poulos, T.L, Gershon, P.D. Deposit date: 2008-10-01 Release date: 2009-06-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase Structure, 17, 2009
2IJN	Isothiazoles as active-site inhibitors of HCV NS5B polymerase Descriptor: (2R,3R)-3-{[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO}-2-CYANO-3-THIOXOPROPANAMIDE, RNA polymerase NS5B Authors: Yan, S, Yao, N. Deposit date: 2006-09-29 Release date: 2006-11-28 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Isothiazoles as active-site inhibitors of HCV NS5B polymerase Bioorg.Med.Chem.Lett., 17, 2007
6IPE	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mg-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPK	Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPM	Binary Complex of Human DNA Polymerase Mu with MgdCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPF	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mn-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPL	Binary Complex of Human DNA Polymerase Mu with MgdATP Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPD	Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPI	Binary Complex of Human DNA Polymerase Mu with MndCTP Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... Authors: Chang, Y.K, Wu, W.J, Tsai, M.D. Deposit date: 2018-11-03 Release date: 2019-05-29 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
8Z8X	Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation Descriptor: PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. Deposit date: 2024-04-22 Release date: 2024-05-29 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024

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