3TAQ
 
 | |
3LC3
 | | Benzothiophene Inhibitors of Factor IXa | | Descriptor: | 1-[5-(3,4-dimethoxyphenyl)-1-benzothiophen-2-yl]methanediamine, CALCIUM ION, Coagulation factor IX | | Authors: | Wang, S, Beck, R. | | Deposit date: | 2010-01-09 | | Release date: | 2010-02-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis.
J.Med.Chem., 53, 2010
|
|
3TEB
 | | endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b | | Descriptor: | Endonuclease/exonuclease/phosphatase, MAGNESIUM ION | | Authors: | Chang, C, Bigelow, L, Muniez, I, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-08-12 | | Release date: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Crystal structure of endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b
To be Published
|
|
3TBF
 | | C-terminal domain of glucosamine-fructose-6-phosphate aminotransferase from Francisella tularensis. | | Descriptor: | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] | | Authors: | Osipiuk, J, Zhou, M, Maltseva, N, Kim, Y, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-08-05 | | Release date: | 2011-08-24 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | C-terminal domain of glucosamine-fructose-6-phosphate aminotransferase from Francisella tularensis.
To be Published
|
|
3LEK
 | | Lectin Domain of Lectinolysin complexed with Lewis B Antigen | | Descriptor: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | | Authors: | Feil, S.C. | | Deposit date: | 2010-01-15 | | Release date: | 2010-12-29 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.
Structure, 20, 2012
|
|
3TGW
 | | Crystal structure of subunit B mutant H156A of the A1AO ATP synthase | | Descriptor: | 2-(2-METHOXYETHOXY)ETHANOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, ... | | Authors: | Tadwal, V.S, Manimekalai, M.S.S, Jeyakanthan, J, Gruber, G. | | Deposit date: | 2011-08-18 | | Release date: | 2012-09-05 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure of subunit A mutants H156A, N157A and N157T of the A1AO ATP synthase
To be Published
|
|
3LF5
 | | Structure of Human NADH cytochrome b5 oxidoreductase (Ncb5or) b5 Domain to 1.25A Resolution | | Descriptor: | Cytochrome b5 reductase 4, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Deng, B, Parthasarathy, S, Wang, W, Gibney, B.R, Battaile, K.P, Lovell, S, Benson, D.R, Zhu, H. | | Deposit date: | 2010-01-15 | | Release date: | 2010-07-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Study of the individual cytochrome b5 and cytochrome b5 reductase domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain.
J.Biol.Chem., 285, 2010
|
|
3LA6
 | | Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Tyrosine-protein kinase wzc | | Authors: | Gruszczyk, J, Nessler, S, Gueguen-Chaignon, V, Vigouroux, A, Bechet, E, Grangeasse, C. | | Deposit date: | 2010-01-06 | | Release date: | 2010-08-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export
Mol.Microbiol., 77, 2010
|
|
3LCE
 | | Crystal Structure of Oxa-10 Beta-Lactamase Covalently Bound to Cyclobutanone Beta-Lactam Mimic | | Descriptor: | (1S,3S,4S,5S)-7,7-dichloro-3-methoxy-2-thiabicyclo[3.2.0]heptan-6-one-4-carboxylic acid, Beta-lactamase OXA-10, GLYCEROL, ... | | Authors: | Gretes, M, Strynadka, N.C.J. | | Deposit date: | 2010-01-10 | | Release date: | 2010-03-09 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Cyclobutanone Analogues of beta-Lactams Revisited: Insights into Conformational Requirements for Inhibition of Serine- and Metallo-beta-Lactamases.
J.Am.Chem.Soc., 132, 2010
|
|
3LFC
 | | Human p38 MAP Kinase in Complex with RL99 | | Descriptor: | (4-{5-[({4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}carbamoyl)amino]-3-tert-butyl-1H-pyrazol-1-yl}phenyl)acetic acid, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | Authors: | Gruetter, C, Simard, J.R, Getlik, M, Rauh, D. | | Deposit date: | 2010-01-16 | | Release date: | 2011-04-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Development of novel thiazole-urea compounds which stabalize the inactive conformation of p38 alpha
To be Published
|
|
3LFP
 | |
3LGY
 | | R178A mutant of the DegS-deltaPDZ protease | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Protease degS | | Authors: | Sohn, J, Grant, R.A, Sauer, R.T. | | Deposit date: | 2010-01-21 | | Release date: | 2010-08-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Allostery is an intrinsic property of the protease domain of DegS: implications for enzyme function and evolution.
J.Biol.Chem., 285, 2010
|
|
3TGZ
 | |
3LEG
 | | Lectin Domain of Lectinolysin complexed with Lewis Y Antigen | | Descriptor: | CALCIUM ION, NICKEL (II) ION, Platelet aggregation factor Sm-hPAF, ... | | Authors: | Feil, S.C. | | Deposit date: | 2010-01-14 | | Release date: | 2010-12-29 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity.
Structure, 20, 2012
|
|
3LHI
 | |
3THM
 | | Crystal structure of Fas receptor extracellular domain in complex with Fab EP6b_B01 | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fab EP6b_B01, ... | | Authors: | Zuger, S, Stirnimann, C, Briand, C, Grutter, M.G. | | Deposit date: | 2011-08-19 | | Release date: | 2012-05-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.
Cell Death Differ., 19, 2012
|
|
3T9O
 | | Regulatory CZB domain of DgcZ | | Descriptor: | Diguanylate cyclase DgcZ, ZINC ION | | Authors: | Zaehringer, F, Schirmer, T. | | Deposit date: | 2011-08-03 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and signaling mechanism of a zinc-sensory diguanylate cyclase.
Structure, 21, 2013
|
|
3T89
 | | Crystal structure of Escherichia coli MenB, the 1,4-dihydroxy-2-naphthoyl-CoA synthase in vitamin K2 biosynthesis | | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL, MALONATE ION | | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | | Deposit date: | 2011-08-01 | | Release date: | 2011-08-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.949 Å) | | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member.
Biochemistry, 50, 2011
|
|
3LI2
 | | Closed Conformation of HtsA Complexed with Staphyloferrin A | | Descriptor: | (2R)-2-(2-{[(1R)-1-carboxy-4-{[(3S)-3,4-dicarboxy-3-hydroxybutanoyl]amino}butyl]amino}-2-oxoethyl)-2-hydroxybutanedioic acid, ACETATE ION, FE (III) ION, ... | | Authors: | Grigg, J.C, Murphy, M.E.P. | | Deposit date: | 2010-01-23 | | Release date: | 2010-02-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Staphylococcus aureus siderophore receptor HtsA undergoes localized conformational changes to enclose staphyloferrin A in an arginine-rich binding pocket.
J.Biol.Chem., 285, 2010
|
|
3LIU
 | |
3LG4
 | | Staphylococcus aureus V31Y, F92I mutant dihydrofolate reductase complexed with NADPH and 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine | | Descriptor: | 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Frey, K.M, Anderson, A.C. | | Deposit date: | 2010-07-08 | | Release date: | 2010-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Predicting resistance mutations using protein design algorithms.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3T9L
 | | Structure of N-terminal DUSP-UBL domains of human USP15 | | Descriptor: | SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 15 | | Authors: | Harper, S, Besong, T.M.D, Emsley, J, Scott, D.J, Dreveny, I. | | Deposit date: | 2011-08-03 | | Release date: | 2011-09-28 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of the USP15 N-Terminal Domains: A beta-Hairpin Mediates Close Association between the DUSP and UBL Domains
Biochemistry, 50, 2011
|
|
3LJN
 | |
3TC8
 | |
3LKO
 | | Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1934 strain | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | Authors: | Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K. | | Deposit date: | 2010-01-27 | | Release date: | 2010-07-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
