PDB: 45118 resultsInfo pagesStatus searchChemie searchBIRD

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7M0B	Pre-catalytic quaternary complex of DNA Polymerase Lambda with bound mismatched DSB and incoming dUMPNPP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2 Å) Cite: Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13, 2022
7M0C	Post-catalytic nicked complex of DNA Polymerase Lambda with bound mismatched DSB substrate Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*AP*GP*TP*GP*CP*T)-3'), ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Comprehensive structural survey of DNA double-strand break synapsis by DNA Polymerase Lambda Not Published
7M08	Post-catalytic nicked complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comprehensive structural survey of DNA double-strand break synapsis by DNA Polymerase Lambda Not Published
7M07	Pre-catalytic ternary complex of DNA Polymerase Lambda with bound 1-nt gapped SSB substrate and incoming dUMPNPP Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... Authors: Kaminski, A.M, Bebenek, K, Pedersen, L.C, Kunkel, T.A. Deposit date: 2021-03-10 Release date: 2022-03-16 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Analysis of diverse double-strand break synapsis with Pol lambda reveals basis for unique substrate specificity in nonhomologous end-joining. Nat Commun, 13, 2022
8S49	CdaA-B06 complex Descriptor: 2-(4-fluorophenyl)acetohydrazide, Diadenylate cyclase, SODIUM ION Authors: Neumann, P, Ficner, R. Deposit date: 2024-02-21 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (1.7 Å) Cite: CdaA-B06 complex To Be Published
8RPL	AMP-forming acetyl-CoA synthetase from Chloroflexota bacterium with bound acetyl AMP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Acetate--CoA ligase, MAGNESIUM ION, ... Authors: Striska, K, Palm, G.J, Lammers, M. Deposit date: 2024-01-16 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (2.37 Å) Cite: The AMP-forming acetyl-CoA-synthetase is regulated by lysine acetylation and has an intrinsic phosphotransacetylase activity to adjust its activity to the cellular acetyl-phosphate level Nature Comm, 2024
8S46	CdaA-E01 complex Descriptor: 2-chlorobenzyl carbamimidothioate, Diadenylate cyclase, SODIUM ION Authors: Neumann, P, Ficner, R. Deposit date: 2024-02-21 Release date: 2024-06-19 Method: X-RAY DIFFRACTION (1.99 Å) Cite: CdaA-E01 complex To Be Published
7RCL	Crystal Structure of ADP-bound Galactokinase Descriptor: ADENOSINE-5'-DIPHOSPHATE, Galactokinase, MAGNESIUM ION, ... Authors: Whitby, F.G, Hall, M.D. Deposit date: 2021-07-07 Release date: 2021-09-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
7RCM	Crystal Structure of ADP-bound Galactokinase Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... Authors: Whitby, F.G. Deposit date: 2021-07-07 Release date: 2021-09-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
6OOI	Crystal structure of triosephosphate isomerase from Schistosoma mansoni in complex with 2PG Descriptor: 2-PHOSPHOGLYCOLIC ACID, CHLORIDE ION, GLYCEROL, ... Authors: Jimenez-Sandoval, P, Brieba, L. Deposit date: 2019-04-23 Release date: 2020-01-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Crystal structures of Triosephosphate Isomerases from Taenia solium and Schistosoma mansoni provide insights for vaccine rationale and drug design against helminth parasites. Plos Negl Trop Dis, 14, 2020
4XND	Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homotryptophan Descriptor: (3S)-3-AMINO-4-(1H-INDOL-3-YL)BUTANOIC ACID, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homotryptophan To Be Published
6B5S	Structure of PfCSP peptide 25 with human antibody CIS42 Descriptor: AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ... Authors: Pancera, M, Weidle, C. Deposit date: 2017-09-29 Release date: 2018-03-21 Last modified: 2019-01-09 Method: X-RAY DIFFRACTION (1.983 Å) Cite: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
4XN1	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Glutamate Descriptor: Aminopeptidase N, GLUTAMIC ACID, MALONATE ION, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Glutamate To Be Published
4XO5	Crystal Structure of E. coli Aminopeptidase N in complex with L-Glutamate Descriptor: Aminopeptidase N, GLUTAMIC ACID, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-16 Release date: 2016-01-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Glutamate To Be Published
5VE2	Crystal structure of enoyl-CoA hydratase/isomerase from Pseudoalteromonas atlantica T6c at 2.3 A resolution. Descriptor: DI(HYDROXYETHYL)ETHER, Enoyl-CoA hydratase, GLYCEROL, ... Authors: Siuda, M.K, Shabalin, I.G, Cooper, D.R, Chapman, H.C, Tkaczuk, K.L, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) Deposit date: 2017-04-03 Release date: 2017-04-19 Last modified: 2019-12-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of enoyl-CoA hydratase/isomerase from Pseudoalteromonas atlantica T6c at 2.3 A resolution. to be published
6Q8U	Structure of the standard kink turn HmKt-7 variant A2bm6A bound with AfL7Ae protein Descriptor: 50S ribosomal protein L7Ae, RNA (5'-R(*CP*GP*GP*CP*GP*AP*AP*GP*(6MZ)P*AP*CP*CP*GP*GP*GP*GP*AP*GP*CP*CP*G)-3'), SODIUM ION Authors: Huang, L, Lilley, D.M.J. Deposit date: 2018-12-16 Release date: 2019-07-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Effect of methylation of adenine N6on kink turn structure depends on location. Rna Biol., 16, 2019
5GS8	Crystal structure of TLA-3 extended-spectrum beta-lactamase Descriptor: Beta-lactamase, CHLORIDE ION, SODIUM ION, ... Authors: Wachino, J, Jin, W, Arakawa, Y. Deposit date: 2016-08-14 Release date: 2017-07-12 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam and OP0595. Antimicrob. Agents Chemother., 61, 2017
6TDS	Crystal structure of the disulfide engineered HLA-A0201 molecule without peptide bound after NaCl wash Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... Authors: Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. Deposit date: 2019-11-10 Release date: 2020-03-25 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
3KZW	Crystal structure of cytosol aminopeptidase from Staphylococcus aureus COL Descriptor: CHLORIDE ION, Cytosol aminopeptidase, PHOSPHATE ION, ... Authors: Hattne, J, Dubrovska, I, Halavaty, A, Minasov, G, Scott, P, Shuvalova, L, Winsor, J, Otwinowski, Z, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2009-12-08 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite:
6GEH	Structure and reactivity of a siderophore-interacting protein from the marine bacterium Shewanella reveals unanticipated functional versatility. Descriptor: DIMETHYL SULFOXIDE, FAD-binding 9, siderophore-interacting domain protein, ... Authors: Trindade, I.B, Silva, J.P.M, Matias, P, Moe, E. Deposit date: 2018-04-26 Release date: 2018-11-21 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Structure and reactivity of a siderophore-interacting protein from the marine bacteriumShewanellareveals unanticipated functional versatility. J. Biol. Chem., 294, 2019
3I24	Crystal Structure of a HIT family hydrolase protein from Vibrio fischeri. Northeast Structural Genomics Consortium target id VfR176 Descriptor: HIT family hydrolase, SODIUM ION Authors: Seetharaman, J, Abashidze, M, Forouhar, F, Janjua, H, Xiao, R, Ciccosanti, C, Foote, E.L, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) Deposit date: 2009-06-29 Release date: 2009-07-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal Structure of a HIT family hydrolase protein from Vibrio fischeri. Northeast Structural Genomics Consortium target id VfR176 To be Published
5OU5	Crystal structure of maize chloroplastic photosynthetic NADP(+)-dependent malic enzyme Descriptor: Malic enzyme, POTASSIUM ION, SODIUM ION Authors: Bovdilova, A, Hoeppner, A, Maurino, V.G. Deposit date: 2017-08-23 Release date: 2018-12-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Molecular adaptations of NADP-malic enzyme for its function in C4photosynthesis in grasses. Nat.Plants, 5, 2019
6WSH	Crystal structure of EutV from Enterococcus faecalis Descriptor: GLYCEROL, MAGNESIUM ION, Response regulator, ... Authors: Ataide, S.F, Walshe, J.L. Deposit date: 2020-05-01 Release date: 2021-05-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structural characterization of the ANTAR antiterminator domain bound to RNA. Nucleic Acids Res., 50, 2022
7Y6I	Cryo-EM structure of human sodium-chloride cotransporter Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q. Deposit date: 2022-06-20 Release date: 2022-11-23 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Cryo-EM structure of the human sodium-chloride cotransporter NCC. Sci Adv, 8, 2022
6LXK	Crystal structure of Z2B3 D102R Fab in complex with influenza virus neuraminidase from A/Serbia/NS-601/2014 (H1N1) Descriptor: CALCIUM ION, Heavy chain of Z2B3-D102R Fab, Light chain of Z2B3-D102R Fab, ... Authors: Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y. Deposit date: 2020-02-11 Release date: 2020-12-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.608 Å) Cite: Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus. Mbio, 11, 2020

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